phenanthrenes has been researched along with Prostatic-Hyperplasia* in 1 studies
1 other study(ies) available for phenanthrenes and Prostatic-Hyperplasia
| Article | Year |
|---|---|
Triptolide reduces prostate size and androgen level on testosterone-induced benign prostatic hyperplasia in Sprague Dawley rats.
Benign prostatic hyperplasia (BPH) is an age-related disease of unknown etiology, characterized by prostatic enlargement coincident with distinct alterations in tissue histology. In the present study, we investigated whether triptolide can prevent testosterone-induced prostatic hyperplasia in rats. Castration was performed via the scrotal route after urethane aesthesia. BPH was induced in experimental groups by daily subcutaneous injections of testosterone propionate (TP) for two weeks. Triptolide was administered daily by oral gavage at a dose of 100 and 50 μg·kg Topics: Androgens; Animals; Diterpenes; Drugs, Chinese Herbal; Epoxy Compounds; Humans; Male; Phenanthrenes; Prostate; Prostatic Hyperplasia; Rats; Rats, Sprague-Dawley; Testosterone; Tripterygium | 2017 |