phenanthrenes and Hepatitis-C

Recent emergence of direct-acting antivirals (DAAs) targeting hepatitis C virus (HCV) proteins has considerably enhanced the success of antiviral therapy. However, the appearance of DAA-resistant-associated variants is a cause of treatment failure, and the high cost of DAAs renders the therapy not accessible in countries with inadequate medical infrastructures. Therefore, the search for new inhibitors with a lower cost of production should be pursued. In this context, the crude extract of

Topics: Antiviral Agents; Cell Line; Drug Resistance, Viral; Genotype; HEK293 Cells; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; Hepatocytes; Humans; Phenanthrenes; Phenethylamines; Plant Extracts; Protease Inhibitors; Replicon; Rhizome; Virus Replication