phenanthrene has been researched along with Chemical and Drug Induced Liver Injury in 2 studies
phenanthrene : A polycyclic aromatic hydrocarbon composed of three fused benzene rings which takes its name from the two terms 'phenyl' and 'anthracene.'
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we have made comparisons of constitutive androstane receptor (CAR) activation and toxic effects on the liver between these two isomers." | 1.51 | Phenanthrene, but not its isomer anthracene, effectively activates both human and mouse nuclear receptor constitutive androstane receptor (CAR) and induces hepatotoxicity in mice. ( Cheng, R; Deng, W; Lu, M; Shi, Z; Wang, XX; Yang, H; Zeng, Y; Zhang, SY; Zhao, LY; Zhu, J, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, H | 1 |
| Shi, Z | 1 |
| Wang, XX | 1 |
| Cheng, R | 1 |
| Lu, M | 1 |
| Zhu, J | 1 |
| Deng, W | 1 |
| Zeng, Y | 1 |
| Zhao, LY | 1 |
| Zhang, SY | 1 |
| Krahn, MM | 1 |
| Myers, MS | 1 |
| Burrows, DG | 1 |
| Malins, DC | 1 |
2 other studies available for phenanthrene and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Phenanthrene, but not its isomer anthracene, effectively activates both human and mouse nuclear receptor constitutive androstane receptor (CAR) and induces hepatotoxicity in mice.
Topics: Animals; Anthracenes; Aryl Hydrocarbon Hydroxylases; Cell Line, Tumor; Chemical and Drug Induced Liv | 2019 |
Determination of metabolites of xenobiotics in the bile of fish from polluted waterways.
Topics: Animals; Benzo(a)pyrene; Bile; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure | 1984 |