phenacetin has been researched along with Liver Neoplasms in 13 studies
Saridon: contains phenacetin, caffeine, propyphenazone & pyrithyldione
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenacetin pharmacokinetics and the recovery of its urinary metabolites were studied in 8 normal subjects, 16 patients with chronic hepatitis B and 12 patients with cirrhosis." | 5.12 | Impaired clearance of phenacetin in hepatic cirrhosis and fibrosis. ( He, P; Li, XD; Liu, HL; Qu, ZQ; Wu, MC; Zhang, X, 2007) |
| "The phenacetin test was performed in 56 normal subjects and 92 HCC patients." | 1.35 | The effect of transcatheter arterial chemoembolization on CYP1A2 activity in patients with hepatocellular carcinoma. ( Ding, N; He, P; Huang, W; Li, XD; Qu, ZQ; Wu, MC; Zhang, SL, 2008) |
| "Phenacetin was most effective followed by N-ethylacetanilide." | 1.26 | Effect of phenacetin and N-alkylacetanilides on N-2-fluorenylacetamide hepatocarcinogenesis. ( Frankel, HH; Weisburger, EK; Yamamoto, RS, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (69.23) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Steinbrecht, S | 1 |
| Pfeifer, N | 1 |
| Herzog, N | 1 |
| Katzenberger, N | 1 |
| Schulz, C | 1 |
| Kammerer, S | 1 |
| Küpper, JH | 1 |
| Pan, X | 1 |
| Li, X | 1 |
| Cui, L | 1 |
| Wang, Q | 1 |
| Huang, W | 1 |
| Qu, ZQ | 2 |
| Li, XD | 2 |
| He, P | 2 |
| Ding, N | 1 |
| Zhang, SL | 1 |
| Wu, MC | 2 |
| Liu, HL | 1 |
| Zhang, X | 1 |
| Baker, AL | 1 |
| Kotake, AN | 1 |
| Schoeller, DA | 1 |
| Macklin, AW | 2 |
| Szot, RJ | 1 |
| Johansson, SL | 1 |
| Scheuer, PJ | 1 |
| Calder, IC | 1 |
| Goss, DE | 1 |
| Williams, PJ | 1 |
| Funder, CC | 1 |
| Green, CR | 1 |
| Ham, KN | 1 |
| Tange, JD | 1 |
| Mitchell, JR | 1 |
| Potter, WZ | 1 |
| Welch, RM | 1 |
| Cuatrecasas, P | 1 |
| Yamamoto, RS | 1 |
| Frankel, HH | 1 |
| Weisburger, EK | 1 |
| Muradian, RE | 1 |
3 reviews available for phenacetin and Liver Neoplasms
| Article | Year |
|---|---|
Clinical utility of breath tests for the assessment of hepatic function.
Topics: Aminopyrine; Breath Tests; Caffeine; Chemical and Drug Induced Liver Injury; Chronic Disease; Cytoch | 1983 |
Long-term effects on the liver.
Topics: Anabolic Agents; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Cholestasis; Chr | 1975 |
Drug metabolism in the production of liver injury.
Topics: Acetaminophen; Acetanilides; Alkylating Agents; Bromobenzenes; Chemical and Drug Induced Liver Injur | 1975 |
2 trials available for phenacetin and Liver Neoplasms
| Article | Year |
|---|---|
Preoperative Phenacetin Metabolism Test in the Prediction of Postoperative Liver Dysfunction of Patients with Hepatocellular Carcinoma.
Topics: Carcinoma, Hepatocellular; Female; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Phenacetin; Po | 2017 |
Impaired clearance of phenacetin in hepatic cirrhosis and fibrosis.
Topics: Acetaminophen; Area Under Curve; Biotransformation; Carcinoma, Hepatocellular; Chemoembolization, Th | 2007 |
8 other studies available for phenacetin and Liver Neoplasms
| Article | Year |
|---|---|
HepG2-1A2 C2 and C7: Lentivirus vector-mediated stable and functional overexpression of cytochrome P450 1A2 in human hepatoblastoma cells.
Topics: Aflatoxin B1; Cell Line, Tumor; Cytochrome P-450 CYP1A2; DNA Fingerprinting; Genetic Vectors; Hepato | 2020 |
The effect of transcatheter arterial chemoembolization on CYP1A2 activity in patients with hepatocellular carcinoma.
Topics: Acetaminophen; Adult; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Cytochrome P-450 CY | 2008 |
Eighteen month oral study of aspirin, phenacetin and caffeine, in C57Bl/6 mice.
Topics: Animals; Aspirin; Caffeine; Carcinogens; Diet; Female; Kidney; Liver; Liver Neoplasms; Male; Mice; M | 1980 |
Carcinogenicity of analgesics: long-term treatment of Sprague-Dawley rats with phenacetin, phenazone, caffeine and paracetamol (acetamidophen).
Topics: Acetaminophen; Adenocarcinoma; Analgesics; Animals; Antipyrine; Caffeine; Carcinogens; Carcinoma, Sq | 1981 |
Neoplasia in the rat induced by N-hydroxyphenacetin, a metabolite of phenacetin.
Topics: Animals; Carcinoma; Carcinoma, Hepatocellular; Kidney Neoplasms; Liver Neoplasms; Male; Phenacetin; | 1976 |
Drug safety: phenacetin.
Topics: Animals; Carcinogens; Liver Neoplasms; Mice; Neoplasms, Experimental; Phenacetin; Rats | 1979 |
Effect of phenacetin and N-alkylacetanilides on N-2-fluorenylacetamide hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Acetanilides; Animals; Liver Neoplasms; Male; Neoplasms, Experimental; Phenac | 1979 |
[Experimental study of the carcinogenicity of phenacetin].
Topics: Adenocarcinoma; Animals; Female; Fibrosarcoma; Leukemia, Experimental; Liver Neoplasms; Lung Neoplas | 1986 |