Page last updated: 2024-11-02

phenacetin and Kidney Neoplasms

phenacetin has been researched along with Kidney Neoplasms in 115 studies

Saridon: contains phenacetin, caffeine, propyphenazone & pyrithyldione

Kidney Neoplasms: Tumors or cancers of the KIDNEY.

Research Excerpts

ExcerptRelevanceReference
"Carcinogenicity of phenacetin (PH) to the urinary tract was tested with the use of spontaneously hydronephrosis-bearing rats."7.68Induction of renal pelvic carcinoma by phenacetin in hydronephrosis-bearing rats of the SD/cShi strain. ( Hayashi, Y; Hosono, M; Iwata, H; Machino, S; Makino, S; Mori, S; Murai, T; Ohara, T; Takeda, R; Takeuchi, Y, 1993)
"Twenty-one of 40 rats fed phenacetin in the diet for up to 86 weeks developed urothelial hyperplasia of the renal papillae."7.65Urothelial hyperplasia of the renal papillae in female Sprague-Dawley rats induced by long term feeding of phenacetin. ( Angervall, L; Johansson, S, 1976)
"A 65-year-old female had been taking analgesics containing phenacetin, because of severe headaches since 1958."4.81[A case of renal pelvic tumor due to phenacetin abuse]. ( Deguchi, T; Hori, T; Kojima, K; Maeda, S; Nishino, Y; Tamaki, M, 2002)
"Carcinogenicity of phenacetin (PH) to the urinary tract was tested with the use of spontaneously hydronephrosis-bearing rats."3.68Induction of renal pelvic carcinoma by phenacetin in hydronephrosis-bearing rats of the SD/cShi strain. ( Hayashi, Y; Hosono, M; Iwata, H; Machino, S; Makino, S; Mori, S; Murai, T; Ohara, T; Takeda, R; Takeuchi, Y, 1993)
"39 carcinomas of the renal pelvis diagnosed between 1968 and 1979 were retrospectively examined for capillary sclerosis in the ureters, which is pathognomonic of phenacetin abuse by the patient."3.66[Abuse of phenacetin-containing analgesics and carcinoma of the renal pelvis (author's transl)]. ( Matejka, M; Syré, G, 1981)
"Twenty-one of 40 rats fed phenacetin in the diet for up to 86 weeks developed urothelial hyperplasia of the renal papillae."3.65Urothelial hyperplasia of the renal papillae in female Sprague-Dawley rats induced by long term feeding of phenacetin. ( Angervall, L; Johansson, S, 1976)
"Most kidney cancers are RCC, and blacks are currently experiencing RCC rates that are higher than any other race."2.41Review of potential risk factors for kidney (renal cell) cancer. ( Moyad, MA, 2001)
" In a group of 274 urological patients, the reasons and consequences of long-term intake of phenacetin-containing compounds are herewith demonstrated."2.36[Causes and consequences of long term consumption of phenacetin-containing analgesics, from the urologist's point of view (author's transl)]. ( Porpáczy, P, 1979)
"Phenacetin is an analgesic that causes renal diseases and cancers of the upper-urinary tract (UUT)."1.40The ban on phenacetin is associated with changes in the incidence trends of upper-urinary tract cancers in Australia. ( Antoni, S; Ferlay, J; Forman, D; Moore, S; Sitas, F; Smith, DP; Soerjomataram, I, 2014)
"Carcinoma in situ was present among 30% of patients with non-invasive high-grade tumours."1.39A population-based study of tumours of the renal pelvis and ureter: incidence, aetiology and histopathological findings. ( Holmäng, S; Holmberg, E; Johansson, SL, 2013)
" Results from this work demonstrate that, in the absence of CYP1A2, phenacetin is more toxic than in controls."1.30Role of CYP1A2 in the toxicity of long-term phenacetin feeding in mice. ( Coakley, CJ; Gonzalez, FJ; Kimura, S; Morishima, H; Peters, JM; Ward, JM, 1999)
"Although heavy or long-term use of analgesics has been related to risk of renal cell cancer in several studies, evidence for such an association remains inconclusive."1.29Use of analgesics and risk of renal cell cancer. ( Chow, WH; Linet, MS; Mandel, JS; McLaughlin, JK; Niwa, S, 1994)
" In addition, positive associations were observed for long-term use of phenacetin-containing analgesics, heavy meat consumption, and heavy tea drinking (females only)."1.27A population--based case--control study of renal cell carcinoma. ( Blot, WJ; Fraumeni, JF; Mandel, JS; McLaughlin, JK; Mehl, ES; Schuman, LM, 1984)
"Phenacetin appeared to enhance the development of renal pelvic tumors in FANFT-induced urinary tract carcinogenesis."1.27The influence of phenacetin or mechanical perforation on the development of renal pelvic and urinary bladder tumors in FANFT-induced urinary tract carcinogenesis. ( Anderström, C; Johansson, SL; von Schultz, L, 1983)
"In a case-control study of 36 men with cancer of the ureter and 307 male controls with the same age distribution tobacco smoking conferred a relative risk for this cancer of 2."1.27Analgesics and tobacco as risk factors for cancer of the ureter and renal pelvis. ( Ford, JM; McCredie, M; Stewart, JH, 1983)
"Of urologic cancers, bladder cancer has been the most intensively studied epidemiologically."1.27Epidemiology and environmental factors in urologic cancer. ( Morrison, AS, 1987)
" Long-term use (greater than 36 mo) of phenacetin-containing products was associated in both sexes with a twofold increased risk for renal cell cancer."1.27Relation of analgesic use to renal cancer: population-based findings. ( Blot, WJ; Fraumeni, JF; McLaughlin, JK; Mehl, ES, 1985)
"4), and no dose-response relationship was demonstrated."1.26Analgesics and cancer of the renal pelvis in New South Wales. ( Ford, JM; McCredie, M; Stewart, JH; Taylor, JS, 1982)

Research

Studies (115)

TimeframeStudies, this research(%)All Research%
pre-199086 (74.78)18.7374
1990's23 (20.00)18.2507
2000's2 (1.74)29.6817
2010's4 (3.48)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Malmström, PU1
Holmäng, S1
Holmberg, E1
Johansson, SL3
Kawamura, Y1
Hayashi, H1
Masumura, K1
Numazawa, S1
Nohmi, T1
Antoni, S1
Soerjomataram, I1
Moore, S1
Ferlay, J1
Sitas, F1
Smith, DP1
Forman, D1
KROGSGAARD, AR1
FRIIS, T1
Bilynskiĭ, BT1
Shparik, IaV1
McLaughlin, JK4
Mandel, JS2
Blot, WJ2
Schuman, LM1
Mehl, ES2
Fraumeni, JF3
Anderström, C1
von Schultz, L1
Novák, J1
Zídek, I1
Burnett, KR2
Miller, JB2
Greenbaum, EI1
McCredie, M10
Stewart, JH10
Ford, JM5
MacLennan, RA1
Kunze, E1
Wöltjen, HH1
Albrecht, H1
Base, J1
Sváb, J1
Navrátil, P1
Mihatsch, MJ2
Hofer, HO1
Gutzwiler, F1
Brunner, FP2
Zollinger, HU1
Blohmé, I1
Johansson, S10
Taylor, JS1
Nakanishi, K1
Kurata, Y1
Oshima, M1
Fukushima, S3
Ito, N1
Eisinger, AJ1
Syré, G1
Matejka, M1
Gonwa, TA1
Corbett, WT1
Schey, HM1
Buckalew, VM1
Bergman, S1
Forrest, J1
Betsill, W1
Gillenwater, J1
Lornoy, W4
Morelle, V3
Becaus, I3
Fonteyne, E3
Mestdagh, J2
Thienpont, L1
Rollier, A1
Van Steenberge, R1
D'Haenens, P1
Petersen, I2
Ohgaki, H3
Ludeke, BI2
Kleihues, P3
Linet, MS2
Chow, WH2
Wacholder, S1
Yu, MC2
Schoenberg, JB1
Lynch, C1
Niwa, S1
Murai, T2
Mori, S2
Hosono, M2
Takeuchi, Y2
Oohara, T1
Makino, S2
Takeda, R2
Meister, P1
Garnerus, H1
Stahl, J1
Machino, S1
Ohara, T1
Hayashi, Y3
Iwata, H1
Day, NE1
Vanchieri, C1
Kliem, V1
Thon, W1
Krautzig, S1
Kolditz, M1
Behrend, M1
Pichlmayr, R1
Koch, KM1
Frei, U1
Brunkhorst, R1
Bringuier, PP1
Sauter, G1
Bilous, M1
Stewart, J2
Vanholder, R1
Billiouw, JM1
Sierens, L1
De Broe, ME1
Onozawa, M1
Johraku, A1
Kojima, T1
Sekido, N1
Miyanaga, N1
Shimazui, T1
Kikuchi, K1
Takeshima, H1
Akaza, H1
Peters, JM1
Morishima, H1
Ward, JM1
Coakley, CJ1
Kimura, S1
Gonzalez, FJ1
Smith, D1
Supramaniam, R1
Williams, S1
Lee, CC1
Wanibuchi, H1
Yamamoto, S1
Hirose, M2
Gago-Dominguez, M1
Yuan, JM1
Castelao, JE1
Ross, RK1
Hobbs, JB1
McCredie, MR1
Moyad, MA1
Kojima, K1
Tamaki, M1
Maeda, S1
Hori, T1
Nishino, Y1
Deguchi, T1
Calder, IC1
Goss, DE1
Williams, PJ1
Funder, CC1
Green, CR1
Ham, KN1
Tange, JD1
Anseline, P1
Howarth, VS1
Richtmann, L1
Thiel, G1
Dubach, UC1
Carro-Ciampi, G1
Gaakeer, HA1
De Ruiter, HJ1
Porpáczy, P1
Bengtsson, U10
Greenbaum, E1
Vaught, JB1
King, CM1
Sorrentino, F1
de Martino, AM1
Handa, SP1
Bovy, P1
Muller, M1
Beaujean, MA1
Rorive, G1
Kliment, J1
Moshakis, V1
Hooper, AA1
Devulder, B1
Mazeman, E1
Houcke, M1
Plouvier, B1
Twiss, EE1
Gratama, S1
Angervall, L11
Prescott, LF1
Gallery, ED1
Rathert, P1
Melchior, H1
Lutzeyer, W1
Wahlgvist, L1
Pollen, JJ1
Levine, E1
Van Blerk, PJ1
Deichgräber, E1
Küng, LG1
Wahlqvist, L5
Haillot, O1
Lanson, Y1
Terao, E1
Yamasaki, I1
Coates, MS1
Disney, AP2
Auld, JJ1
Jensen, OM1
Knudsen, JB1
Tomasson, H1
Sørensen, BL1
Mathew, TH1
Becaus, S1
de Vleeschouwer, M1
Thienpoint, L1
Steffens, J1
Nagel, R1
Palvio, DH1
Andersen, JC1
Falk, E1
Togei, K1
Sano, N1
Maeda, T1
Shibata, M1
Otsuka, H1
Morrison, AS1
Kimura, M1
Matsubara, M1
Suwa, J1
Matsuyama, K1
Shishido, S1
Chino, I1
Campo, B1
Zanitzer, L1
Torelli, T1
Bacchioni, AM1
Ferrari, C1
Ordesi, G1
Macchi, RM1
Carter, JJ1
Turner, J1
Mahony, JF1
Immich, H1
Bengtsson, V1
Bentsson, U1
Leistenschneider, W1
Ehmann, R1
Clemmesen, J1
Liu, T1
Smith, GW1
Rankin, JT1
Juusela, H1
Bock, KD1
Hogrefe, J1
Hoybye, G1
Nielsen, OE1
Gottfries, A1
Nilsson, S1
Grob, HU1
Adam, WR1
Dawborn, JK1
Price, CG1
Riddell, J1
Story, H1
Ekman, H1
Lehmann, L1
Zetterlund, CG1
Zsigmond, M1
Hultengren, N1
Lagergren, C1
Ljungqvist, A1
MacEwan, DW1
Rosenthall, L1

Reviews

13 reviews available for phenacetin and Kidney Neoplasms

ArticleYear
[Carcinogenicity of various drugs].
    Voprosy onkologii, 1984, Volume: 30, Issue:8

    Topics: Adult; Animals; Anti-Bacterial Agents; Arsenicals; Barbiturates; Brain Neoplasms; Carcinogens; Child

1984
[Phenacetin abuse I. Occurrence, per capita consumption and costs of treatment].
    Schweizerische medizinische Wochenschrift, 1980, Jan-28, Volume: 110, Issue:4

    Topics: Adult; Aged; Female; Humans; Kidney Neoplasms; Kidney Pelvis; Legislation, Drug; Male; Middle Aged;

1980
Phenacetin.
    IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 1980, Volume: 24

    Topics: Animals; Biotransformation; Chemical Phenomena; Chemistry; Cocarcinogenesis; Kidney Neoplasms; Mice;

1980
Review of potential risk factors for kidney (renal cell) cancer.
    Seminars in urologic oncology, 2001, Volume: 19, Issue:4

    Topics: Age Factors; Carcinoma, Renal Cell; Contraceptives, Oral; Diet; Humans; Hypertension; Incidence; Kid

2001
[A case of renal pelvic tumor due to phenacetin abuse].
    Hinyokika kiyo. Acta urologica Japonica, 2002, Volume: 48, Issue:5

    Topics: Aged; Analgesics, Non-Narcotic; Carcinoma, Transitional Cell; Female; Headache; Humans; Kidney Neopl

2002
[Tumors of the efferent parts of the urinary tract and abuse of analgesics].
    Schweizerische medizinische Wochenschrift, 1978, Jul-08, Volume: 108, Issue:27

    Topics: Acetaminophen; Adult; Analgesics; Carcinoma, Squamous Cell; Choriocarcinoma; Female; Humans; Kidney

1978
Phenacetin abuse: a review.
    Toxicology, 1978, Volume: 10, Issue:4

    Topics: Anemia, Hemolytic; Animals; Carcinoma; Erythrocytes; Female; Hemoglobins; Humans; Kidney; Kidney Dis

1978
[Causes and consequences of long term consumption of phenacetin-containing analgesics, from the urologist's point of view (author's transl)].
    Wiener klinische Wochenschrift. Supplementum, 1979, Volume: 104

    Topics: Analgesics; Anemia; Austria; Caffeine; Humans; Kidney Neoplasms; Kidney Papillary Necrosis; Kidney P

1979
Prevention of renal disease.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1979, Volume: 16

    Topics: Anti-Glomerular Basement Membrane Disease; Antipyrine; Caffeine; Chronic Disease; Female; Glomerulon

1979
[A case of renal pelvic tumor due to phenacetin abuse].
    Hinyokika kiyo. Acta urologica Japonica, 1990, Volume: 36, Issue:8

    Topics: Aged; Aged, 80 and over; Bone Neoplasms; Carcinoma, Transitional Cell; Humans; Kidney Neoplasms; Kid

1990
Tumours of the renal pelvis and ureter. Observations in 170 patients.
    British journal of urology, 1988, Volume: 61, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Child; Female; Humans; Kidney

1988
Unravelling analgesic nephropathy.
    Food and cosmetics toxicology, 1972, Volume: 10, Issue:5

    Topics: Acetaminophen; Analgesics; Animals; Aspirin; Carcinoma, Transitional Cell; Female; Humans; Kidney Ne

1972
Phenacetin as a carcinogen: an unsatisfactory picture.
    Food and cosmetics toxicology, 1970, Volume: 8, Issue:5

    Topics: Female; Humans; Kidney Neoplasms; Male; Phenacetin; Pyelonephritis; Sweden; Urinary Bladder Neoplasm

1970

Other Studies

102 other studies available for phenacetin and Kidney Neoplasms

ArticleYear
Drugs and risk of cancer.
    Scandinavian journal of urology, 2017, Volume: 51, Issue:3

    Topics: Analgesics; Carcinoma, Transitional Cell; Drug Misuse; History, 20th Century; Humans; Kidney Neoplas

2017
A population-based study of tumours of the renal pelvis and ureter: incidence, aetiology and histopathological findings.
    Scandinavian journal of urology, 2013, Volume: 47, Issue:6

    Topics: Aged; Blood Vessels; Carcinoma in Situ; Female; Humans; Incidence; Kidney Neoplasms; Kidney Pelvis;

2013
Genotoxicity of phenacetin in the kidney and liver of Sprague-Dawley gpt delta transgenic rats in 26-week and 52-week repeated-dose studies.
    Toxicology, 2014, Oct-03, Volume: 324

    Topics: Analgesics, Non-Narcotic; Animals; Cell Transformation, Neoplastic; Female; Hypoxanthine Phosphoribo

2014
The ban on phenacetin is associated with changes in the incidence trends of upper-urinary tract cancers in Australia.
    Australian and New Zealand journal of public health, 2014, Volume: 38, Issue:5

    Topics: Adult; Aged; Analgesics, Non-Narcotic; Australia; Female; Humans; Incidence; Kidney Diseases; Kidney

2014
ISOTOPE NEPHROGRAPHY WITH 131-I "HIPPURAN". I. TECHNIQUE AND EXPERIENCE IN VARIOUS MEDICAL RENAL DISEASES.
    Acta medica Scandinavica, 1964, Volume: 176

    Topics: Biomedical Research; Contrast Media; Creatine; Creatinine; Drug Therapy; Glomerulonephritis; Hydrone

1964
A population--based case--control study of renal cell carcinoma.
    Journal of the National Cancer Institute, 1984, Volume: 72, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Cystitis; Female; Germany; Humans; Kidney Diseases; Kidney Neoplasms; M

1984
The influence of phenacetin or mechanical perforation on the development of renal pelvic and urinary bladder tumors in FANFT-induced urinary tract carcinogenesis.
    Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology, 1983, Volume: 91, Issue:5

    Topics: Animals; Carcinoma, Squamous Cell; Carcinosarcoma; Disease Susceptibility; FANFT; Hyperplasia; Kidne

1983
[Phenacetin as a carcinogen for the urothelium].
    Casopis lekaru ceskych, 1983, Sep-16, Volume: 122, Issue:37

    Topics: Aged; Carcinoma, Papillary; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Phenacetin

1983
Transitional cell carcinoma: rapid development in phenacetin abuse.
    AJR. American journal of roentgenology, 1980, Volume: 134, Issue:6

    Topics: Aged; Carcinoma, Transitional Cell; Humans; Kidney Neoplasms; Kidney Pelvis; Male; Neoplasm Staging;

1980
Phenacetin-containing analgesics and cancer of the bladder or renal pelvis in women.
    British journal of urology, 1983, Volume: 55, Issue:2

    Topics: Adult; Female; Humans; Kidney Neoplasms; Kidney Pelvis; Phenacetin; Risk; Smoking; Urinary Bladder N

1983
Absence of a complete carcinogenic effect of phenacetin on the quiescent and proliferating urothelium stimulated by partial cystectomy. A 2-year feeding study in rats.
    Urologia internationalis, 1983, Volume: 38, Issue:2

    Topics: Animals; Cell Division; Cocarcinogenesis; Epithelium; Female; Hyperplasia; Kidney; Kidney Medulla; K

1983
Analgesics and tobacco as risk factors for cancer of the ureter and renal pelvis.
    The Journal of urology, 1983, Volume: 130, Issue:1

    Topics: Aged; Carcinoma; Female; Humans; Kidney Neoplasms; Kidney Pelvis; Male; Middle Aged; Phenacetin; Ris

1983
[Problems with phenacetin in urology].
    Sbornik vedeckych praci Lekarske fakulty Karlovy univerzity v Hradci Kralove. Supplementum, 1980, Volume: 23, Issue:4

    Topics: Adult; Aged; Carcinoma, Papillary; Female; Humans; Kidney Diseases; Kidney Neoplasms; Kidney Papilla

1980
Renal pelvic neoplasms and atypical urothelium in patients with end-stage analgesic nephropathy.
    Kidney international, 1981, Volume: 20, Issue:5

    Topics: Acute Kidney Injury; Adult; Age Factors; Epithelium; Female; Humans; Hyperplasia; Kidney Neoplasms;

1981
Analgesics and cancer of the renal pelvis in New South Wales.
    Cancer, 1982, Jun-15, Volume: 49, Issue:12

    Topics: Age Factors; Aged; Analgesics; Aspirin; Australia; Female; Humans; Kidney Neoplasms; Kidney Pelvis;

1982
Carcinogenicity of phenacetin: long-term feeding study in B6c3f1 mice.
    International journal of cancer, 1982, Apr-15, Volume: 29, Issue:4

    Topics: Adenoma; Animal Feed; Animals; Carcinoma; Female; Kidney Neoplasms; Leukemia, Experimental; Male; Mi

1982
Analgesic nephropathy.
    British journal of hospital medicine, 1981, Volume: 25, Issue:3

    Topics: Adult; Analgesics; Aspirin; Female; Humans; Kidney Diseases; Kidney Neoplasms; Male; Middle Aged; Ph

1981
[Abuse of phenacetin-containing analgesics and carcinoma of the renal pelvis (author's transl)].
    Wiener klinische Wochenschrift, 1981, Jun-26, Volume: 93, Issue:13

    Topics: Capillaries; Carcinoma, Transitional Cell; Creatinine; Female; Humans; Kidney Neoplasms; Kidney Pelv

1981
Carcinogenicity of analgesics: long-term treatment of Sprague-Dawley rats with phenacetin, phenazone, caffeine and paracetamol (acetamidophen).
    International journal of cancer, 1981, Volume: 27, Issue:4

    Topics: Acetaminophen; Adenocarcinoma; Analgesics; Animals; Antipyrine; Caffeine; Carcinogens; Carcinoma, Sq

1981
Analgesic-associated nephropathy and transitional cell carcinoma of the urinary tract.
    Annals of internal medicine, 1980, Volume: 93, Issue:2

    Topics: Adult; Aged; Carcinoma, Transitional Cell; Female; Humans; Kidney Diseases; Kidney Failure, Chronic;

1980
Acquired upper ureteral stricture in a phenacetin abuser.
    The Journal of urology, 1980, Volume: 124, Issue:6

    Topics: Adenocarcinoma; Aged; Female; Humans; Kidney Failure, Chronic; Kidney Neoplasms; Phenacetin; Substan

1980
Malignant uroepithelial tumors of the upper urinary tract in sixteen patients with analgesic nephropathy.
    Acta clinica Belgica, 1980, Volume: 35, Issue:3

    Topics: Adult; Analgesics; Belgium; Female; Humans; Kidney; Kidney Diseases; Kidney Neoplasms; Male; Middle

1980
[p53 mutation in phenacetin-induced urothelial carcinomas].
    Verhandlungen der Deutschen Gesellschaft fur Pathologie, 1993, Volume: 77

    Topics: Aged; Amino Acid Sequence; Base Sequence; Carcinoma, Transitional Cell; Exons; Female; Frameshift Mu

1993
Analgesics and cancers of the renal pelvis and ureter.
    International journal of cancer, 1995, Jul-04, Volume: 62, Issue:1

    Topics: Acetaminophen; Adult; Aged; Analgesics; Aspirin; Case-Control Studies; Female; Humans; Kidney Neopla

1995
Use of analgesics and risk of renal cell cancer.
    International journal of cancer, 1994, Nov-15, Volume: 59, Issue:4

    Topics: Acetaminophen; Adult; Aged; Aspirin; Carcinoma, Renal Cell; Case-Control Studies; Drug Combinations;

1994
Effect of phenacetin pretreatment on renal pelvic carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine in NON/Shi mice of both sexes.
    Teratogenesis, carcinogenesis, and mutagenesis, 1994, Volume: 14, Issue:4

    Topics: Animals; Butylhydroxybutylnitrosamine; Female; Hydronephrosis; Hyperplasia; Kidney Neoplasms; Kidney

1994
[Explosive metastasis of a cancer of the kidney pelvis in analgesic kidney].
    Der Pathologe, 1994, Volume: 15, Issue:1

    Topics: Carcinoma, Transitional Cell; Cell Transformation, Neoplastic; Humans; Kidney; Kidney Diseases; Kidn

1994
p53 mutations in phenacetin-associated human urothelial carcinomas.
    Carcinogenesis, 1993, Volume: 14, Issue:10

    Topics: Aged; Base Sequence; Codon; Exons; Female; Genes, p53; Humans; Kidney Neoplasms; Kidney Pelvis; Male

1993
Induction of renal pelvic carcinoma by phenacetin in hydronephrosis-bearing rats of the SD/cShi strain.
    Cancer research, 1993, Sep-15, Volume: 53, Issue:18

    Topics: Animals; Hydronephrosis; Kidney Neoplasms; Kidney Pelvis; Male; Phenacetin; Rats

1993
Different roles for phenacetin and paracetamol in cancer of the kidney and renal pelvis.
    International journal of cancer, 1993, Jan-21, Volume: 53, Issue:2

    Topics: Acetaminophen; Adult; Aged; Aspirin; Carcinoma, Renal Cell; Case-Control Studies; Drug Combinations;

1993
Australian study links certain analgesics to renal cancers.
    Journal of the National Cancer Institute, 1993, Feb-17, Volume: 85, Issue:4

    Topics: Acetaminophen; Australia; Carcinoma, Renal Cell; Humans; Kidney Neoplasms; Phenacetin; Risk

1993
High mortality from urothelial carcinoma despite regular tumor screening in patients with analgesic nephropathy after renal transplantation.
    Transplant international : official journal of the European Society for Organ Transplantation, 1996, Volume: 9, Issue:3

    Topics: Acetaminophen; Adult; Aged; Analgesics; Carcinoma, Renal Cell; Female; Humans; Kidney Failure, Chron

1996
Carcinomas of the renal pelvis associated with smoking and phenacetin abuse: p53 mutations and polymorphism of carcinogen-metabolising enzymes.
    International journal of cancer, 1998, Oct-23, Volume: 79, Issue:5

    Topics: Aged; Arylamine N-Acetyltransferase; Carcinogens; Cytochrome P-450 CYP1A1; Female; Genes, p53; Gluta

1998
Phenacetin or anything: what makes or made analgesics nephrotoxic?
    Acta clinica Belgica, 1998, Volume: 53, Issue:5

    Topics: Analgesics, Non-Narcotic; Belgium; Chemistry, Pharmaceutical; Disease Progression; Drug Combinations

1998
Analgesic nephropathy: clinical features and pathogenesis. Original data on the incidence and prevalence in a single renal unit.
    Acta clinica Belgica, 1998, Volume: 53, Issue:5

    Topics: Adult; Age Factors; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin

1998
On a nephrotoxic and carcinogenic slimming regimen.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1999, Volume: 33, Issue:6

    Topics: Analgesics; Animals; Aristolochic Acids; Balkan Nephropathy; Carcinogens; Carcinoma, Transitional Ce

1999
[A case of synchronous multifocal urothelial tumors in a patient with phenacetin abuse].
    Hinyokika kiyo. Acta urologica Japonica, 1999, Volume: 45, Issue:4

    Topics: Aged; Carcinoma, Transitional Cell; Humans; Kidney Neoplasms; Kidney Pelvis; Male; Neoplasms, Multip

1999
Role of CYP1A2 in the toxicity of long-term phenacetin feeding in mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 1999, Volume: 50, Issue:1

    Topics: Acetaminophen; Animals; Carcinogens; Carcinoma; Cytochrome P-450 CYP1A2; Female; Kidney Neoplasms; M

1999
Observations on the effect of abolishing analgesic abuse and reducing smoking on cancers of the kidney and bladder in New South Wales, Australia, 1972-1995.
    Cancer causes & control : CCC, 1999, Volume: 10, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Female; Humans; Incidence; Ki

1999
Molecular cytogenetic identification of cyclin D1 gene amplification in a renal pelvic tumor attributed to phenacetin abuse.
    Pathology international, 1999, Volume: 49, Issue:7

    Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Carcinoma, Transitional Cell; Chromosomes, Human;

1999
Regular use of analgesics is a risk factor for renal cell carcinoma.
    British journal of cancer, 1999, Volume: 81, Issue:3

    Topics: Acetaminophen; Adult; Aged; Analgesics; Aspirin; Carcinoma, Renal Cell; Case-Control Studies; Dose-R

1999
Morphologic evidence that analgesic-induced kidney pathology contributes to the progression of tumors of the renal pelvis.
    Cancer, 1999, Oct-15, Volume: 86, Issue:8

    Topics: Age Factors; Aged; Analgesics, Non-Narcotic; Calcinosis; Carcinoma, Squamous Cell; Disease Progressi

1999
Neoplasia in the rat induced by N-hydroxyphenacetin, a metabolite of phenacetin.
    Pathology, 1976, Volume: 8, Issue:1

    Topics: Animals; Carcinoma; Carcinoma, Hepatocellular; Kidney Neoplasms; Liver Neoplasms; Male; Phenacetin;

1976
A case of transitional cell carcinoma of the renal pelvis, clear cell renal carcinoma, and analgesic nephropathy.
    The Australian and New Zealand journal of surgery, 1977, Volume: 47, Issue:4

    Topics: Adenocarcinoma; Aged; Carcinoma, Transitional Cell; Female; Humans; Kidney Diseases; Kidney Neoplasm

1977
Another risk of phenacetin containing analgesic.
    The New Zealand medical journal, 1977, Apr-27, Volume: 85, Issue:586

    Topics: Carcinoma, Transitional Cell; Female; Humans; Kidney Neoplasms; Kidney Pelvis; Male; Middle Aged; Ph

1977
Carcinoma of the renal pelvis following the abuse of phenacetin-containing analgesic drugs.
    British journal of urology, 1979, Volume: 51, Issue:3

    Topics: Adult; Aged; Carcinogens; Carcinoma, Transitional Cell; Cytological Techniques; Drug Combinations; F

1979
Analgesic associated urinary-tract tumors.
    Annals of internal medicine, 1979, Volume: 90, Issue:6

    Topics: Aged; Carcinoma, Transitional Cell; Humans; Kidney Neoplasms; Male; Phenacetin

1979
Phenacetin studies.
    Science (New York, N.Y.), 1979, Nov-09, Volume: 206, Issue:4419

    Topics: Acute Kidney Injury; Animals; Biotransformation; Carcinogens; Humans; Kidney Neoplasms; Mice; Mutati

1979
Chronic interstitial nephritis as a cause of tumours of the upper urinary tract. A hypothesis.
    Urologia internationalis, 1979, Volume: 34, Issue:6

    Topics: Chronic Disease; Humans; Kidney Calculi; Kidney Neoplasms; Kidney Pelvis; Nephritis, Interstitial; P

1979
Analgesic nephropathy and urothelial carcinoma.
    Canadian Medical Association journal, 1979, Oct-06, Volume: 121, Issue:7

    Topics: Analgesics; Aspirin; Caffeine; Carcinoma, Transitional Cell; Codeine; Female; Humans; Kidney Neoplas

1979
[Development of malignant uroepithelial neoplasms in the upper urinary tracts in nephropathies caused by analgesic abuse: clinical study based on 16 cases].
    Journal d'urologie et de nephrologie, 1979, Volume: 85, Issue:9

    Topics: Analgesics; Female; Humans; Kidney Diseases; Kidney Neoplasms; Kidney Pelvis; Middle Aged; Phenaceti

1979
[Phenacetin abuse and uroepithelial tumors].
    Acta clinica Belgica, 1979, Volume: 34, Issue:4

    Topics: Female; Humans; Kidney Neoplasms; Male; Middle Aged; Phenacetin; Substance-Related Disorders

1979
[Renal pelvis tumours and abuse of analgesics (author's transl)].
    Bratislavske lekarske listy, 1979, Volume: 72, Issue:6

    Topics: Female; Humans; Kidney Neoplasms; Kidney Pelvis; Middle Aged; Phenacetin; Substance-Related Disorder

1979
Analgesic nephropathy and transitional cell carcinoma.
    Postgraduate medical journal, 1978, Volume: 54, Issue:630

    Topics: Adult; Carcinoma, Transitional Cell; Female; Humans; Kidney Neoplasms; Phenacetin; Substance-Related

1978
[Dysimmunopathy and excreto-urinary cancer caused by chronic phenacetin poisoning].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1978, Volume: 23, Issue:8

    Topics: Chronic Disease; Female; Humans; Immunologic Deficiency Syndromes; Kidney Calices; Kidney Neoplasms;

1978
[A patient with terminal renal insufficiency].
    Nederlands tijdschrift voor geneeskunde, 1977, Jun-25, Volume: 121, Issue:26

    Topics: Acute Kidney Injury; Calcium Carbonate; Carcinoma, Transitional Cell; Humans; Iatrogenic Disease; Ki

1977
Urothelial hyperplasia of the renal papillae in female Sprague-Dawley rats induced by long term feeding of phenacetin.
    Acta pathologica et microbiologica Scandinavica. Section A, Pathology, 1976, Volume: 84, Issue:4

    Topics: Animals; Chronic Disease; Female; Hyperplasia; Kidney Neoplasms; Kidney Pelvis; Phenacetin; Pyelitis

1976
Urothelial changes of the renal papillae in Sprague-Dawley rats induced by long term feeding of phenacetin.
    Acta pathologica et microbiologica Scandinavica. Section A, Pathology, 1976, Volume: 84, Issue:5

    Topics: Animals; Chronic Disease; Ear Canal; Ear Neoplasms; Female; Hyperplasia; Kidney; Kidney Cortex; Kidn

1976
Analgesic nephropathy--the international experience.
    Australian and New Zealand journal of medicine, 1976, Volume: 6 Suppl 1

    Topics: Analgesics; Animals; Drug Synergism; Humans; Kidney Neoplasms; Kidney Papillary Necrosis; Kidney Pel

1976
Analgesic abuse and kidney disease.
    Australian and New Zealand journal of medicine, 1976, Volume: 6, Issue:5

    Topics: Analgesics; Animals; Aspirin; Australia; Carcinoma, Transitional Cell; Female; Humans; Kidney Diseas

1976
Phenacetin: a carcinogen for the urinary tract?
    The Journal of urology, 1975, Volume: 113, Issue:5

    Topics: Aged; Carcinogens; Carcinoma, Transitional Cell; Female; Humans; Kidney Neoplasms; Male; Middle Aged

1975
Phenacetin abuse and renal pelvic carcinoma.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2

    Topics: Adult; Aged; Carcinoma, Papillary; Creatinine; Female; Follow-Up Studies; Hematuria; Humans; Hydroxy

1975
The angiographic evaluation of renal pelvic carcinoma.
    British journal of urology, 1975, Volume: 47, Issue:4

    Topics: Aged; Angiography; Carcinoma, Transitional Cell; Diagnosis, Differential; Female; Hematuria; Humans;

1975
Urothelial renal pelvic tumours in phenacetin abusers.
    Acta radiologica: diagnosis, 1975, Volume: 16, Issue:6

    Topics: Adult; Aged; Creatinine; Female; Humans; Kidney Neoplasms; Kidney Pelvis; Male; Middle Aged; Phenace

1975
[Hypernephroid carcinoma and carcinoma of the urinary tract following phenacetin abuse].
    Schweizerische medizinische Wochenschrift, 1976, Jan-10, Volume: 106, Issue:2

    Topics: Adult; Aged; Female; Humans; Kidney Neoplasms; Kidney Pelvis; Male; Middle Aged; Phenacetin; Substan

1976
A clinicopathologic and prognostic study of epithelial tumors of the renal pelvis.
    Cancer, 1976, Volume: 37, Issue:3

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Female; Hematuria; Humans; Kidn

1976
[Epidemiology and detection of renal cancer in adults].
    La Revue du praticien, 1992, May-15, Volume: 42, Issue:10

    Topics: Adult; Age Factors; Aged; Diet; Ethnicity; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Occu

1992
Geographical distribution of cancers of the kidney and urinary tract and analgesic nephropathy in Australia and New Zealand.
    Australian and New Zealand journal of medicine, 1990, Volume: 20, Issue:5

    Topics: Adolescent; Adult; Australia; Child; Child, Preschool; Female; Humans; Kidney Diseases; Kidney Failu

1990
The Copenhagen case-control study of renal pelvis and ureter cancer: role of analgesics.
    International journal of cancer, 1989, Dec-15, Volume: 44, Issue:6

    Topics: Aspirin; Case-Control Studies; Denmark; Female; Humans; Kidney Neoplasms; Kidney Pelvis; Male; Occup

1989
The effect of withdrawal of phenacetin-containing analgesics on the incidence of kidney and urothelial cancer and renal failure.
    Clinical nephrology, 1989, Volume: 31, Issue:1

    Topics: Analgesics; Australia; Chemistry, Pharmaceutical; Cohort Studies; Female; Humans; Kidney Failure, Ch

1989
Renal cell carcinoma, a new complication of analgesic nephropathy.
    Lancet (London, England), 1986, May-31, Volume: 1, Issue:8492

    Topics: Adult; Aged; Carcinoma, Renal Cell; Female; Humans; Kidney Diseases; Kidney Neoplasms; Male; Middle

1986
Does paracetamol cause urothelial cancer or renal papillary necrosis?
    Nephron, 1988, Volume: 49, Issue:4

    Topics: Acetaminophen; Carcinoma, Transitional Cell; Female; Humans; Kidney Neoplasms; Kidney Papillary Necr

1988
[Capillary sclerosis in the mucous membrane of the urinary tract: a reliable histological marker for analgesic abuse].
    Ugeskrift for laeger, 1987, Sep-28, Volume: 149, Issue:40

    Topics: Capillaries; Carcinoma, Transitional Cell; Female; Humans; Kidney Failure, Chronic; Kidney Neoplasms

1987
Carcinogenicity of bucetin in (C57BL/6 X C3H)F1 mice.
    Journal of the National Cancer Institute, 1987, Volume: 79, Issue:5

    Topics: Aminophenols; Animals; Body Weight; Carcinoma, Renal Cell; Dose-Response Relationship, Drug; Female;

1987
Epidemiology and environmental factors in urologic cancer.
    Cancer, 1987, Aug-01, Volume: 60, Issue:3 Suppl

    Topics: Environmental Exposure; Epidemiologic Methods; Female; Genital Neoplasms, Male; Humans; Kidney Neopl

1987
[A case of renal pelvic tumor due to phenacetin abuse].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1987, Volume: 78, Issue:2

    Topics: Carcinoma, Transitional Cell; Female; Humans; Kidney Neoplasms; Kidney Pelvis; Middle Aged; Phenacet

1987
Renal cell carcinoma and transitional cell carcinomas of the pelvis and bladder in a patient affected by chronic renal failure due to abuse of phenacetin.
    Tumori, 1986, Apr-30, Volume: 72, Issue:2

    Topics: Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Humans; Kidney Failure, Chronic; Kidney Neoplas

1986
Phenacetin and papillary necrosis: independent risk factors for renal pelvic cancer.
    Kidney international, 1986, Volume: 30, Issue:1

    Topics: Aged; Female; Humans; Kidney; Kidney Neoplasms; Kidney Papillary Necrosis; Kidney Pelvis; Male; Midd

1986
[Does phenacetin cause cancer?].
    Deutsche medizinische Wochenschrift (1946), 1987, Jan-02, Volume: 112, Issue:1

    Topics: Adolescent; Adult; Aged; Female; Germany, West; Humans; Kidney Neoplasms; Male; Middle Aged; Phenace

1987
Relation of analgesic use to renal cancer: population-based findings.
    National Cancer Institute monograph, 1985, Volume: 69

    Topics: Acetaminophen; Adult; Analgesics; Aspirin; Carcinoma, Renal Cell; Female; Humans; Kidney Neoplasms;

1985
Phenacetin and cancers of the urinary tract.
    The New England journal of medicine, 1985, Dec-05, Volume: 313, Issue:23

    Topics: Adenocarcinoma; Adult; Aged; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Phenacetin; Urinar

1985
Phenacetin.
    Lancet (London, England), 1969, Feb-01, Volume: 1, Issue:7588

    Topics: Acetaminophen; Antipyrine; Denmark; Humans; Kidney Diseases; Kidney Neoplasms; Kidney Papillary Necr

1969
Analgesic abuse and tumours of renal pelvis.
    Lancet (London, England), 1970, Feb-07, Volume: 1, Issue:7641

    Topics: Female; Humans; Kidney Neoplasms; Kidney Pelvis; Male; Phenacetin; Substance-Related Disorders

1970
[Carcinoma of the renal pelvis following phenacetin abuse].
    Schweizerische medizinische Wochenschrift, 1973, Mar-24, Volume: 103, Issue:12

    Topics: Adenocarcinoma, Scirrhous; Adult; Age Factors; Aged; Autopsy; Carcinoma, Squamous Cell; Female; Huma

1973
Statistical studies in the aetiology of malignant neoplasms.
    Acta pathologica et microbiologica Scandinavica. Supplement, 1974, Volume: Suppl 247

    Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Coffee; Denmark; Female; Humans; Infa

1974
Renal pelvic tumour associated with analgesic abuse.
    Canadian Medical Association journal, 1972, Oct-21, Volume: 107, Issue:8

    Topics: Adenocarcinoma; Aged; Alcoholism; Analgesics; Aspirin; Caffeine; Codeine; Drug Synergism; Female; Hu

1972
Carcinoma of the renal pelvis and its relationship to analgesic abuse.
    Annales chirurgiae et gynaecologiae Fenniae, 1973, Volume: 62, Issue:6

    Topics: Adult; Aged; Analgesics; Carcinoma; Carcinoma, Papillary; Carcinoma, Transitional Cell; Female; Foll

1973
Uroepithelial tumors of the renal pelvis associated with abuse of phenacetin-containing analgesics.
    Cancer, 1974, Volume: 33, Issue:3

    Topics: Adult; Aged; Autopsy; Female; Follow-Up Studies; Humans; Kidney; Kidney Diseases; Kidney Neoplasms;

1974
Phenacetin and renal pelvic carcinoma.
    Clinical nephrology, 1974, Volume: 2, Issue:4

    Topics: Age Factors; Antipyrine; Caffeine; Female; Humans; Kidney Failure, Chronic; Kidney Neoplasms; Kidney

1974
[Abuse of analgesics and malignant tumours of the efferent urinary tracts].
    Munchener medizinische Wochenschrift (1950), 1972, Apr-07, Volume: 114, Issue:14

    Topics: Adenocarcinoma; Adult; Age Factors; Analgesics; Carcinoma, Papillary; Carcinoma, Squamous Cell; Fema

1972
Renal pelvic carcinoma in phenacetin abusers.
    Scandinavian journal of urology and nephrology, 1971, Volume: 5, Issue:2

    Topics: Anemia; Carcinoma, Transitional Cell; Female; Hematuria; Humans; Kidney Neoplasms; Kidney Papillary

1971
[Long-term consumption of phenacetin-containing drugs in uroepithelial urinary tract tumors].
    Nordisk medicin, 1971, Oct-07, Volume: 86, Issue:40

    Topics: Female; Humans; Kidney Neoplasms; Kidney Pelvis; Male; Phenacetin; Substance-Related Disorders; Uret

1971
[Phenacetin abuse and cancer of the kidney pelvis].
    Helvetica chirurgica acta, 1971, Volume: 38, Issue:5

    Topics: Female; Humans; Kidney Neoplasms; Kidney Pelvis; Middle Aged; Papilloma; Phenacetin; Substance-Relat

1971
Phenacetin and bladder cancer.
    British medical journal, 1969, Dec-20, Volume: 4, Issue:5685

    Topics: Humans; Kidney Neoplasms; Occupational Diseases; Phenacetin; Tryptophan; Urinary Bladder Neoplasms

1969
[Phenacetin-containing drugs and carcinoma of the urinary tract].
    Lakartidningen, 1969, Oct-29, Volume: 66, Issue:44

    Topics: Humans; Kidney Neoplasms; Kidney Pelvis; Phenacetin; Smoking; Substance-Related Disorders; Urinary B

1969
Anaplastic transitional-cell carcinoma of the renal pelvis in association with analgesic abuse.
    The Medical journal of Australia, 1970, May-30, Volume: 1, Issue:22

    Topics: Adult; Anuria; Aspirin; Autopsy; Blood Chemical Analysis; Caffeine; Carcinoma, Transitional Cell; Fe

1970
[Abuse of phenacetin-containing analgesics--kidney pelvis neoplasms].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1970, Nov-15, Volume: 90, Issue:22

    Topics: Acetaminophen; Drug Synergism; Humans; Kidney Neoplasms; Phenacetin

1970
Renal pelvic carcinoma in Sweden 1962-63.
    Acta pathologica et microbiologica Scandinavica. Section A, Pathology, 1971, Volume: 79, Issue:3

    Topics: Autopsy; Female; Humans; Kidney Neoplasms; Kidney Papillary Necrosis; Kidney Pelvis; Lymphatic Metas

1971
Transitional cell tumors of the renal pelvis in analgesic abusers.
    Scandinavian journal of urology and nephrology, 1968, Volume: 2, Issue:3

    Topics: Adult; Aged; Carcinoma, Transitional Cell; Chronic Disease; Female; Humans; Kidney Neoplasms; Kidney

1968
Renal pelvic carcinoma in a Swedish district with abuse of a phenacetin-containing drug.
    British journal of urology, 1969, Volume: 41, Issue:4

    Topics: Adult; Aged; Carcinoma, Transitional Cell; Female; Humans; Kidney Neoplasms; Kidney Pelvis; Male; Mi

1969
Carcinoma of the renal pelvis in renal papillary necrosis.
    Acta chirurgica Scandinavica, 1965, Volume: 130, Issue:4

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Female; Humans; Kidney Neoplasm

1965
Assessment of excretory urography and radioisotope renal scanning in diseases of the kidneys.
    Radiology, 1966, Volume: 86, Issue:6

    Topics: Adult; Cysts; Female; Humans; Infarction; Kidney; Kidney Calculi; Kidney Diseases; Kidney Neoplasms;

1966