phenacetin has been researched along with Innate Inflammatory Response in 8 studies
Saridon: contains phenacetin, caffeine, propyphenazone & pyrithyldione
Excerpt | Relevance | Reference |
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"Plasma concentrations and pharmacokinetics of phenacetin, a CYP1A2 substrate were determined in normal and experimentally induced inflamed rats by turpentine oil to know the role of inflammation on the pharmacokinetics of phenacetin and formation of its active metabolite (paracetamol) by CYP1A2 in wistar albino rats, weighing about 200-250 g that were randomly divided into two groups consisting six in each group." | 7.81 | Turpentine oil induced inflammation decreases absorption and increases distribution of phenacetin without altering its elimination process in rats. ( Anand Kumar, P; Prasad, VG; Rao, GS; Ravi Kumar, P; Vivek, Ch, 2015) |
"Plasma concentrations and pharmacokinetics of phenacetin, a CYP1A2 substrate were determined in normal and experimentally induced inflamed rats by turpentine oil to know the role of inflammation on the pharmacokinetics of phenacetin and formation of its active metabolite (paracetamol) by CYP1A2 in wistar albino rats, weighing about 200-250 g that were randomly divided into two groups consisting six in each group." | 3.81 | Turpentine oil induced inflammation decreases absorption and increases distribution of phenacetin without altering its elimination process in rats. ( Anand Kumar, P; Prasad, VG; Rao, GS; Ravi Kumar, P; Vivek, Ch, 2015) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (75.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (25.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Saunders, MJ | 1 |
Edwards, BS | 1 |
Zhu, J | 1 |
Sklar, LA | 1 |
Graves, SW | 1 |
Prasad, VG | 1 |
Vivek, Ch | 1 |
Anand Kumar, P | 1 |
Ravi Kumar, P | 1 |
Rao, GS | 1 |
WAGNER-JAUREGG, T | 1 |
JAHN, U | 1 |
BUECH, O | 1 |
WHITEHOUSE, MW | 1 |
Brune, K | 1 |
Glenn, EM | 1 |
Bowman, BJ | 1 |
Rohloff, NA | 1 |
MacDonald, WC | 1 |
Boyd, EM | 1 |
Hottenroth, SM | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
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A Prospective, Randomized, Double-blind Study Assessing the Efficacy of Intravenous (IV) Ibuprofen Versus IV Acetaminophen for the Treatment of Pain Following Orthopaedic Low Extremity Surgery[NCT03771755] | 62 participants (Actual) | Interventional | 2017-07-01 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 review available for phenacetin and Innate Inflammatory Response
Article | Year |
---|---|
[Analgesics: pharmacologic properties as a basis for rational therapy].
Topics: Acetylcholine; Aminopyrine; Analgesics; Animals; Aspirin; Central Nervous System; Dogs; Encephalitis | 1978 |
7 other studies available for phenacetin and Innate Inflammatory Response
Article | Year |
---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Turpentine oil induced inflammation decreases absorption and increases distribution of phenacetin without altering its elimination process in rats.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Biotransformation; Chromatography, High Pressure L | 2015 |
[The antiphlogistic testing of known antirheumatics on kaolin-induced rat paw edema].
Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Antipyrine; Azoles; Edema; | 1962 |
A BIOCHEMICAL DISTINCTION BETWEEN NON-STEROID ANTI-INFLAMMATORY AND ANALGESIC DRUGS.
Topics: Acetaminophen; Acetanilides; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Ag | 1963 |
Anti-inflammatory and PG inhibitory effects of phenacetin and acetaminophen.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Carrageenan; Cyclooxygen | 1977 |
Correlation of mucosal histology and aspirin intake in chronic gastric ulcer.
Topics: Adult; Aged; Aspirin; Caffeine; Chronic Disease; Epithelium; Female; Gastric Mucosa; Gastritis; Huma | 1973 |
The toxicity of phenacetin at the range of the oral LD50(100 days) in albino rats.
Topics: Animals; Asthenia; Ataxia; Caffeine; Chemical and Drug Induced Liver Injury; Cyanosis; Dehydration; | 1968 |