phenacetin has been researched along with Hyperplasia in 14 studies
Saridon: contains phenacetin, caffeine, propyphenazone & pyrithyldione
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mechanical perforation of the urinary bladder of Sprague-Dawley rats and subsequent administration of phenacetin in the diet induced urothelial hyperplasia in 11 of 12 rats." | 7.66 | Urothelial hyperplasia of the urinary bladder of the rat induced by mechanical perforation and phenacetin treatment. ( Johansson, S, 1978) |
| "Twenty-one of 40 rats fed phenacetin in the diet for up to 86 weeks developed urothelial hyperplasia of the renal papillae." | 7.65 | Urothelial hyperplasia of the renal papillae in female Sprague-Dawley rats induced by long term feeding of phenacetin. ( Angervall, L; Johansson, S, 1976) |
| "Mechanical perforation of the urinary bladder of Sprague-Dawley rats and subsequent administration of phenacetin in the diet induced urothelial hyperplasia in 11 of 12 rats." | 3.66 | Urothelial hyperplasia of the urinary bladder of the rat induced by mechanical perforation and phenacetin treatment. ( Johansson, S, 1978) |
| "Twenty-one of 40 rats fed phenacetin in the diet for up to 86 weeks developed urothelial hyperplasia of the renal papillae." | 3.65 | Urothelial hyperplasia of the renal papillae in female Sprague-Dawley rats induced by long term feeding of phenacetin. ( Angervall, L; Johansson, S, 1976) |
| "Phenacetin appeared to enhance the development of renal pelvic tumors in FANFT-induced urinary tract carcinogenesis." | 1.27 | The influence of phenacetin or mechanical perforation on the development of renal pelvic and urinary bladder tumors in FANFT-induced urinary tract carcinogenesis. ( Anderström, C; Johansson, SL; von Schultz, L, 1983) |
| "Treatment with caffeine after BBN had no enhancing effect and caffeine alone caused no remarkable changes." | 1.26 | Effect of phenacetin and caffeine on the urinary bladder of rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine. ( Fukushima, S; Ito, N; Nakanishi, K; Ogiso, T; Shibata, M; Shirai, T, 1978) |
| "Phenacetin is an aromatic amide with N-hydroxylated metabolites, closely related to known carcinogenic amines like the naphthylamines which earlier caused occupational bladder cancer." | 1.26 | Malignancies of the urinary tract and their relation to analgesic abuse. ( Angervall, L; Bengtsson, U; Johansson, S, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (92.86) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anderström, C | 2 |
| Johansson, SL | 3 |
| von Schultz, L | 1 |
| Kunze, E | 2 |
| Wöltjen, HH | 2 |
| Hartmann, B | 1 |
| Engelhardt, W | 1 |
| Albrecht, H | 1 |
| Blohmé, I | 1 |
| Johansson, S | 5 |
| Murai, T | 1 |
| Mori, S | 1 |
| Hosono, M | 1 |
| Takeuchi, Y | 1 |
| Oohara, T | 1 |
| Makino, S | 1 |
| Takeda, R | 1 |
| Fukushima, S | 2 |
| Nakanishi, K | 1 |
| Shibata, M | 1 |
| Shirai, T | 1 |
| Ogiso, T | 1 |
| Ito, N | 1 |
| Bengtsson, U | 1 |
| Angervall, L | 3 |
| Radio, SJ | 1 |
| Saidi, J | 1 |
| Sakata, T | 1 |
| Bach, PH | 1 |
| Bridges, JW | 1 |
| Riede, UN | 1 |
| Torhorst, J | 1 |
| Rohr, HP | 1 |
14 other studies available for phenacetin and Hyperplasia
| Article | Year |
|---|---|
The influence of phenacetin or mechanical perforation on the development of renal pelvic and urinary bladder tumors in FANFT-induced urinary tract carcinogenesis.
Topics: Animals; Carcinoma, Squamous Cell; Carcinosarcoma; Disease Susceptibility; FANFT; Hyperplasia; Kidne | 1983 |
The combined effect of mechanical trauma and phenacetin or sodium saccharin on the rat urinary bladder.
Topics: Animals; Body Weight; Feeding Behavior; Female; Hyperplasia; Male; Phenacetin; Rats; Rats, Inbred St | 1983 |
Animal experiments regarding a possible carcinogenic effect of phenacetin on the resting and proliferating urothelium stimulated by cyclophosphamide.
Topics: Animals; Cell Division; Cocarcinogenesis; Cyclophosphamide; Diet; Endothelium; Female; Hyperplasia; | 1983 |
Absence of a complete carcinogenic effect of phenacetin on the quiescent and proliferating urothelium stimulated by partial cystectomy. A 2-year feeding study in rats.
Topics: Animals; Cell Division; Cocarcinogenesis; Epithelium; Female; Hyperplasia; Kidney; Kidney Medulla; K | 1983 |
Renal pelvic neoplasms and atypical urothelium in patients with end-stage analgesic nephropathy.
Topics: Acute Kidney Injury; Adult; Age Factors; Epithelium; Female; Humans; Hyperplasia; Kidney Neoplasms; | 1981 |
Effect of phenacetin pretreatment on renal pelvic carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine in NON/Shi mice of both sexes.
Topics: Animals; Butylhydroxybutylnitrosamine; Female; Hydronephrosis; Hyperplasia; Kidney Neoplasms; Kidney | 1994 |
Effect of phenacetin and caffeine on the urinary bladder of rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Caffeine; Hyperplasia; Male; Neoplasms, Experimental; Nitrosa | 1978 |
Malignancies of the urinary tract and their relation to analgesic abuse.
Topics: Analgesics; Animals; Carcinogens; Drug Combinations; Female; Hematuria; Humans; Hyperplasia; Kidney | 1978 |
Urothelial hyperplasia of the urinary bladder of the rat induced by mechanical perforation and phenacetin treatment.
Topics: Animals; Hyperplasia; Phenacetin; Rats; Urinary Bladder; Urinary Bladder Diseases | 1978 |
Urothelial hyperplasia of the renal papillae in female Sprague-Dawley rats induced by long term feeding of phenacetin.
Topics: Animals; Chronic Disease; Female; Hyperplasia; Kidney Neoplasms; Kidney Pelvis; Phenacetin; Pyelitis | 1976 |
Urothelial changes of the renal papillae in Sprague-Dawley rats induced by long term feeding of phenacetin.
Topics: Animals; Chronic Disease; Ear Canal; Ear Neoplasms; Female; Hyperplasia; Kidney; Kidney Cortex; Kidn | 1976 |
The effects of acetaminophen, antipyrine and phenacetin on rat urothelial cell proliferation.
Topics: Acetaminophen; Animals; Antipyrine; Cell Division; Epithelial Cells; Epithelium; Hyperplasia; Kidney | 1989 |
Chemically induced renal papillary necrosis and upper urothelial carcinoma. Part 2.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Biotransformatio | 1985 |
Focal proliferation of the smooth endoplasmic reticulum in the cells of the straight part of the proximal kidney tubule.
Topics: Animals; Aspirin; Cell Aggregation; Cytoplasmic Granules; Endoplasmic Reticulum; Hydrocarbons, Bromi | 1973 |