phalloidine has been researched along with Leukemia-L5178* in 1 studies
1 other study(ies) available for phalloidine and Leukemia-L5178
Article | Year |
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Nuclear actin and transport of RNA.
The role of nuclear actin filaments in the RNA transport was investigated. Mouse lymphoma cells, L5178Y, were labeled for 20 min with 3H-uridine, and the isolated nuclei were incubated in a medium consisting of 0.25 M sucrose, 10 mM Tris-HCl (pH 7.5), 2 mM CaCl2, 1 mM ATP and 1mM PMSF. Release of the rapidly labeled RNA from the nuclei was temperature-dependent and was stimulated by ATP. Phalloidin, an inhibitor of actin filament depolymerization, had no effect on the system at 10 or 100 micrograms/ml. Therefore, actin filament depolymerization may not be involved in the transport of RNA. Topics: Actins; Animals; Biological Transport; Cell Nucleus; Kinetics; Leukemia L5178; Mice; Phalloidine; RNA; Tumor Cells, Cultured | 1987 |