phaclofen has been researched along with Epilepsy, Absence in 2 studies
phaclofen: peripheral & central baclofen & GABA antagonist; structure given in first source
Epilepsy, Absence: A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Banerjee, PK | 1 |
| Snead, OC | 2 |
2 other studies available for phaclofen and Epilepsy, Absence
| Article | Year |
|---|---|
Presynaptic gamma-hydroxybutyric acid (GHB) and gamma-aminobutyric acidB (GABAB) receptor-mediated release of GABA and glutamate (GLU) in rat thalamic ventrobasal nucleus (VB): a possible mechanism for the generation of absence-like seizures induced by GH
Topics: Action Potentials; Animals; Baclofen; Epilepsy, Absence; Extracellular Space; GABA-B Receptor Antago | 1995 |
Antiabsence seizure activity of specific GABAB and gamma-Hydroxybutyric acid receptor antagonists.
Topics: Animals; Anticonvulsants; Baclofen; Benzocycloheptenes; Electroencephalography; Epilepsy, Absence; G | 1996 |