phaclofen has been researched along with Disease Models, Animal in 9 studies
phaclofen: peripheral & central baclofen & GABA antagonist; structure given in first source
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our findings indicated that PTZ-induced seizure showed not only decrease in GABABR expression but also cause neuronal apoptosis in the developing rat brain." | 1.39 | Decreased GABABR expression and increased neuronal cell death in developing rat brain after PTZ-induced seizure. ( Al-Qahtani, MH; Ansari, SA; Bibi, F; Karim, S; Kim, MO; Naseer, MI; Ullah, I; Ullah, N, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Khakpoor, M | 1 |
| Vaseghi, S | 1 |
| Mohammadi-Mahdiabadi-Hasani, MH | 1 |
| Nasehi, M | 3 |
| Zarrabian, S | 1 |
| Farrahizadeh, M | 1 |
| Zarrindast, MR | 2 |
| Bolton, MM | 1 |
| Heaney, CF | 1 |
| Murtishaw, AS | 1 |
| Sabbagh, JJ | 1 |
| Magcalas, CM | 1 |
| Kinney, JW | 1 |
| Khanegheini, A | 1 |
| Silva, JR | 1 |
| Silva, ML | 1 |
| Prado, WA | 1 |
| Naseer, MI | 1 |
| Ullah, I | 1 |
| Al-Qahtani, MH | 1 |
| Karim, S | 1 |
| Ullah, N | 1 |
| Ansari, SA | 1 |
| Kim, MO | 1 |
| Bibi, F | 1 |
| Brailowsky, S | 1 |
| Montiel, T | 1 |
| Meneses, S | 1 |
| Di Scala, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Benefit of Acupuncture Combined to Regional Analgesia for Post Operative Pain Relief After Hysterectomy[NCT06002464] | 72 participants (Anticipated) | Interventional | 2023-09-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for phaclofen and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
The effect of GABA-B receptors in the basolateral amygdala on passive avoidance memory impairment induced by MK-801 in rats.
Topics: Animals; Avoidance Learning; Baclofen; Basolateral Nuclear Complex; Behavior, Animal; Disease Models | 2021 |
The role of CA3 GABA
Topics: 2-Amino-5-phosphonovalerate; Animals; Anxiety; Avoidance Learning; Baclofen; CA3 Region, Hippocampal | 2017 |
Postnatal alterations in GABAB receptor tone produce sensorimotor gating deficits and protein level differences in adulthood.
Topics: Acoustic Stimulation; Age Factors; Animals; Animals, Newborn; Baclofen; Body Weight; Brain; Disease | 2015 |
The modulatory effect of CA1 GABAb receptors on ketamine-induced spatial and non-spatial novelty detection deficits with respect to Ca(2+).
Topics: Analysis of Variance; Animals; Baclofen; CA1 Region, Hippocampal; Calcium; Calcium Channel Blockers; | 2015 |
Analgesia induced by 2- or 100-Hz electroacupuncture in the rat tail-flick test depends on the activation of different descending pain inhibitory mechanisms.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Antagonists; Analgesia; Anesthetics, Intravenous; Animals; A | 2011 |
Decreased GABABR expression and increased neuronal cell death in developing rat brain after PTZ-induced seizure.
Topics: Animals; Animals, Newborn; Baclofen; Caspase 3; Cell Death; Disease Models, Animal; Electroencephalo | 2013 |
Effects of GABAB receptor antagonists on two models of focal epileptogenesis.
Topics: Animals; Baclofen; Disease Models, Animal; Epilepsies, Partial; GABA Antagonists; GABA-B Receptor An | 1995 |