pha-408 has been researched along with Arthritis--Rheumatoid* in 1 studies
1 other study(ies) available for pha-408 and Arthritis--Rheumatoid
Article | Year |
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Aminopyridinecarboxamide-based inhibitors: Structure-activity relationship.
Series of aminopyridinecarboxamide-based inhibitors were synthesized and tested against human recombinant IKK-2 and in IL-1beta stimulated synovial fibroblasts. The 2-amino-5-chloropyridine-4-carboxamides were identified as the most potent inhibitors with improved cellular activity. Topics: Amides; Amino Acid Sequence; Aminopyrine; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Fibroblasts; Humans; I-kappa B Kinase; I-kappa B Proteins; Interleukin-1beta; Joint Capsule; Molecular Sequence Data; Structure-Activity Relationship | 2010 |