pha-408 and Arthritis--Rheumatoid

pha-408 has been researched along with Arthritis--Rheumatoid* in 1 studies

Other Studies

1 other study(ies) available for pha-408 and Arthritis--Rheumatoid

ArticleYear
Aminopyridinecarboxamide-based inhibitors: Structure-activity relationship.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Series of aminopyridinecarboxamide-based inhibitors were synthesized and tested against human recombinant IKK-2 and in IL-1beta stimulated synovial fibroblasts. The 2-amino-5-chloropyridine-4-carboxamides were identified as the most potent inhibitors with improved cellular activity.

    Topics: Amides; Amino Acid Sequence; Aminopyrine; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Fibroblasts; Humans; I-kappa B Kinase; I-kappa B Proteins; Interleukin-1beta; Joint Capsule; Molecular Sequence Data; Structure-Activity Relationship

2010