pf 5901 has been researched along with Bronchial Hyperreactivity in 4 studies
alpha-pentyl-3-(2-quinolinylmethoxy)benzenemethanol: structure given in first source; platelet activating factor antagonist
Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zamboni, R | 1 |
| Belley, M | 1 |
| Champion, E | 1 |
| Charette, L | 1 |
| DeHaven, R | 1 |
| Frenette, R | 1 |
| Gauthier, JY | 1 |
| Jones, TR | 1 |
| Leger, S | 1 |
| Masson, P | 1 |
| Herd, CM | 2 |
| Donigi-Gale, D | 3 |
| Shoupe, TS | 2 |
| Burroughs, DA | 1 |
| Yeadon, M | 1 |
| Page, CP | 3 |
| Seeds, EA | 1 |
| Kilfeather, S | 1 |
| Okiji, S | 1 |
| Schoupe, TS | 1 |
4 other studies available for pf 5901 and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Development of a novel series of styrylquinoline compounds as high-affinity leukotriene D4 receptor antagonists: synthetic and structure-activity studies leading to the discovery of (+-)-3-[[[3-[2-(7-chloro-2-quinolinyl)-(E)-ethenyl]phenyl][[3- (dimethyla
Topics: Animals; Bronchial Hyperreactivity; Guinea Pigs; Magnetic Resonance Spectroscopy; Propionates; Quino | 1992 |
Effect of a 5-lipoxygenase inhibitor and leukotriene antagonist (PF 5901) on antigen-induced airway responses in neonatally immunized rabbits.
Topics: Administration, Inhalation; Airway Resistance; Alternaria; Animals; Animals, Newborn; Bronchial Hype | 1994 |
Role of lipoxygenase metabolites in platelet-activating factor- and antigen-induced bronchial hyperresponsiveness and eosinophil infiltration.
Topics: Animals; Benzofurans; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Guinea Pigs; Histamin | 1995 |
Effect of a 5-lipoxygenase inhibitor and leukotriene antagonist (PF 5901) on PAF-induced airway responses in neonatally immunized rabbits.
Topics: Administration, Inhalation; Allergens; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fl | 1992 |