pf-00299804 and Necrosis

pf-00299804 has been researched along with Necrosis* in 1 studies

Other Studies

1 other study(ies) available for pf-00299804 and Necrosis

ArticleYear
Investigation of dacomitinib on reducing cell necrosis and enhancing cell apoptosis in C6 glioma rat model by MRI.
    Bioscience reports, 2019, 03-29, Volume: 39, Issue:3

    Glioma is one of the most epidemic and obstinate types of cancer in the central nervous system (CNS) with poor survival rate. Dacomitinib inhibited cell viability and proliferation of epidermal growth factor receptor (. A C6 rat glioma model was evaluated using proton magnetic resonance spectroscopy (. The obtained data indicated that metabolite ratios were significantly decreased (all. The results demonstrated that the Dacomitinib could suppress glioma cell necrosis and proliferation.

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Glioma; Humans; Ki-67 Antigen; Male; Necrosis; Proton Magnetic Resonance Spectroscopy; Quinazolinones; Rats, Sprague-Dawley

2019