perylene has been researched along with Necrosis in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (4.26) | 18.2507 |
| 2000's | 16 (34.04) | 29.6817 |
| 2010's | 26 (55.32) | 24.3611 |
| 2020's | 3 (6.38) | 2.80 |
| Authors | Studies |
|---|---|
| Arous, D; Berg, K; Grigalavicius, M; Juzeniene, A; Mastrangelopoulou, M; Ménard, M; Skarpen, E; Theodossiou, TA | 1 |
| Farsad, K; Han, X; Jahangiri, Y; Moses, A; St Lorenz, A; Taratula, O; Xu, K; Yu, G | 1 |
| Bolton, MD; de Jonge, R; Ebert, MK; Friesen, TL; Neubauer, JD; Rangel, LI; Secor, GA; Spanner, RE; Stukenbrock, EH; Taliadoros, D; Thomma, BPHJ; Wang, X | 1 |
| Duan, X; Jiang, C; Jin, Q; Sun, Z; Ye, W; Yin, Z; Zhang, D; Zhang, J | 1 |
| Fang, Z; Gao, M; Huang, D; Jiang, C; Jiang, X; Kong, M; Li, Y; Liu, W; Ni, Y; Sun, Z; Wang, X; Yao, N; Zhang, J | 1 |
| Chen, F; Cona, MM; Feng, Y; Gheysens, O; Li, Y; Ni, Y; Nuyts, J; Oyen, R; Rezaei, A; Van Slambrouck, K; Verbruggen, A; Vunckx, K; Zhou, L | 1 |
| Bottiroli, G; Bottone, MG; Croce, AC; Malatesta, M; Pellicciari, C; Santin, G; Scovassi, AI | 1 |
| Alpizar, YA; Bauwens, M; Chen, F; Cona, MM; de Witte, P; Feng, Y; Li, J; Ni, Y; Oyen, R; Sun, Z; Talavera, K; Verbruggen, A; Zhang, J | 1 |
| Bauwens, M; Bucerius, J; De Saint-Hubert, M; Deckers, N; Douma, K; Drummen, M; Granton, P; Hendrikx, G; Kusters, D; Mottaghy, FM; Reutelingsperger, CP | 1 |
| Chen, F; Jiang, B; Ni, Y; Wang, J | 1 |
| Chen, F; Cona, MM; Feng, Y; Li, J; Ni, Y; Oyen, R; Verbruggen, A; Witte, Pd | 1 |
| Cona, MM; Fang, Z; Gao, M; Ji, Y; Jiang, C; Jiang, X; Li, Y; Liu, W; Ni, Y; Sun, Z; Wang, J; Wang, Q; Wang, X; Yao, N; Yin, Z; Zhan, Y; Zhang, J | 1 |
| Cona, MM; Feng, Y; Li, Y; Ni, Y; Oyen, R; Verbruggen, A; Zhang, J | 1 |
| Ni, Y; Qi, X; Shao, H; Sun, Z; Xu, K; Zhang, J | 1 |
| Joniova, J; Miskovsky, P; Misuth, M; Nadova, Z; Sureau, F | 1 |
| Gao, M; Huang, D; Ji, Y; Jiang, C; Li, Y; Liu, W; Liu, X; Ni, Y; Sun, Z; Yao, N; Yin, Z; Zhang, J | 1 |
| Feng, Y; Gao, M; Huang, D; Jiang, C; Jiang, X; Jing, S; Li, Y; Liu, W; Ni, Y; Peng, F; Wang, X; Zhang, D; Zhang, J | 1 |
| Feng, Y; Gao, M; Huang, D; Ji, Y; Jiang, C; Li, Y; Liu, W; Liu, X; Lou, B; Ni, Y; Sun, Z; Wang, Q; Yao, N; Yin, Z; Zhang, J | 1 |
| Chen, F; Dai, X; Li, Y; Ni, Y; Shao, H; Sun, Z; Xu, K; Zhang, J | 1 |
| Gao, M; Huang, D; Jiang, C; Liu, X; Ni, Y; Peng, F; Sun, Z; Yin, Z; Zhang, D; Zhang, J | 1 |
| Jiang, C; Jin, Q; Li, J; Ni, Y; Song, S; Wang, C; Wang, Q; Yang, S; Yin, Z; Zhang, D; Zhang, J | 1 |
| Feng, Y; Gao, M; Huang, D; Jiang, C; Ni, Y; Shao, H; Sun, Z; Wang, X; Yang, S; Yin, Z; Zhang, D; Zhang, J | 1 |
| Chen, L; Feng, Y; Jiang, C; Jin, Q; Li, J; Ni, Y; Song, S; Wang, C; Wang, Q; Yang, S; Yin, Z; Zhang, J | 1 |
| Gao, L; Gao, M; Ma, T; Ni, Y; Shan, X; Shao, H; Xu, K; Yao, N; Zhang, J | 1 |
| De Saint-Hubert, M; Mortelmans, L; Mottaghy, FM; Prinsen, K; Verbruggen, A | 1 |
| de Witte, P; Lerut, E; Marysael, T; Ni, Y | 1 |
| Bormans, G; Cona, MM; de Witte, PA; Fonge, H; Li, J; Marysael, T; Ni, Y; Roskams, T; Van de Putte, M; Verbruggen, A | 1 |
| Bauwens, M; Bormans, G; de Witte, P; Marysael, T; Ni, Y; Rozenski, J | 1 |
| Davids, LM; Sharma, KV | 1 |
| Chung, KR; Daub, ME; Herrero, S | 1 |
| Bay, BH; Du, HY; Olivo, M; Tan, BK | 1 |
| Olivo, M; Ren, MQ; Soo, KC; Tan, PH; Thong, PS; Watt, F | 1 |
| Olivo, M; Soo, KC; Yee, KK | 1 |
| Bormans, GM; Chen, F; de Witte, PA; Huyghe, D; Marchal, G; Mortelmans, L; Ni, Y; Nuyts, J; Verbeke, K; Verbruggen, AM | 1 |
| Bay, BH; Du, HY; Li, Y; Olivo, M; Yip, GW | 1 |
| Bormans, G; Fonge, H; Jin, L; Ni, Y; Verbruggen, A; Wang, H | 1 |
| Fedorocko, P; Hofmanová, J; Horváth, V; Jamborová, E; Kleban, J; Kozubík, A; Mikes, J; Sacková, V; Vaculová, A | 1 |
| Chen, F; de Witte, PA; Ni, Y; Van de Putte, M; Wang, H | 2 |
| Bormans, G; Feng, Y; Fonge, H; Mortelmans, L; Ni, Y; Nuyts, J; Verbruggen, A; Vunckx, K; Wang, H | 1 |
| Davids, LM; Kacerovská, D; Kidson, SH; Kleemann, B; Pizinger, K | 1 |
| De Witte, PA; Ni, Y; Van de Putte, M | 1 |
| Agostinis, P; Assefa, Z; Courtois, S; de Witte, P; Declercq, W; Merlevede, W; Vandenabeele, P; Vandenheede, JR; Vantieghem, A | 1 |
| Aizman, I; Kaplinsky, C; Lavie, G; Mandel, M; Mazur, Y; Meruelo, D; Toren, A | 1 |
| Hájiková, M; Lacková, A; Mirossay, A; Mirossay, L; Mojzis, J; Tóthová, J | 1 |
| Crescenzi, E; Paba, V; Palumbo, G; Quarto, M; Varriale, L | 1 |
| Coppola, E; Palumbo, G; Quarto, M; Varriale, L; Veneziani, BM | 1 |
3 review(s) available for perylene and Necrosis
| Article | Year |
|---|---|
Necrosis avidity: a newly discovered feature of hypericin and its preclinical applications in necrosis imaging.
Topics: Anthracenes; Humans; Necrosis; Optical Imaging; Perylene; Staining and Labeling | 2013 |
Molecular imaging of cell death.
Topics: Animals; Annexin A5; Anthracenes; Antibodies, Monoclonal; Apoptosis; Bacteriocins; Cell Death; Glucaric Acid; Humans; Indoles; Models, Animal; Molecular Diagnostic Techniques; Molecular Probe Techniques; Myocardial Infarction; Necrosis; Organometallic Compounds; Organotechnetium Compounds; Peptides; Perylene; Radiopharmaceuticals; Stroke; Sulfonamides; Synaptotagmin I | 2009 |
Reactive oxygen species in plant pathogenesis: the role of perylenequinone photosensitizers.
Topics: Apoptosis; Host-Pathogen Interactions; Necrosis; Oxidation-Reduction; Perylene; Photosensitizing Agents; Plant Diseases; Plants; Quinones; Reactive Oxygen Species | 2013 |
44 other study(ies) available for perylene and Necrosis
| Article | Year |
|---|---|
Photodynamic Efficacy of Cercosporin in 3D Tumor Cell Cultures.
Topics: Cell Line, Tumor; Humans; Microscopy, Confocal; Necrosis; Perylene; Photochemotherapy; Photosensitizing Agents; Spheroids, Cellular | 2020 |
Biodegradable Hypericin-Containing Nanoparticles for Necrosis Targeting and Fluorescence Imaging.
Topics: Animals; Anthracenes; Cell Line, Tumor; Female; Humans; Mice; Nanoparticles; Necrosis; Neoplasms; Optical Imaging; Perylene | 2020 |
Identification and characterization of Cercospora beticola necrosis-inducing effector CbNip1.
Topics: Beta vulgaris; Cercospora; Fungal Proteins; Genome, Fungal; Host-Pathogen Interactions; Necrosis; Perylene; Phenotype; Phylogeny; Plant Diseases; Plant Leaves; Virulence; Virulence Factors | 2021 |
Radioiodinated hypericin disulfonic acid sodium salts as a DNA-binding probe for early imaging of necrotic myocardium.
Topics: Animals; Anthracenes; Cattle; Cell Line; Cell Survival; DNA; Heart; Iodine Radioisotopes; Male; Mice; Myocardium; Necrosis; Perylene; Random Allocation; Rats; Rats, Sprague-Dawley; Sulfonic Acids | 2017 |
Necrosis affinity evaluation of 131I-hypericin in a rat model of induced necrosis.
Topics: Animals; Anthracenes; Area Under Curve; Half-Life; Iodine Isotopes; Isotope Labeling; Male; Necrosis; Perylene; Radiopharmaceuticals; Rats; Rats, Wistar; Tissue Distribution | 2013 |
Comparative study of iodine-123-labeled hypericin and (99m)Tc-labeled hexakis [2-methoxy isobutyl isonitrile] in a rabbit model of myocardial infarction.
Topics: Animals; Anthracenes; Autoradiography; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Gamma Cameras; Half-Life; Heart; Iodine Radioisotopes; Male; Myocardial Infarction; Myocardium; Necrosis; Perylene; Rabbits; Radionuclide Imaging; Radiopharmaceuticals; Technetium; Technetium Tc 99m Sestamibi; Tissue Distribution; Tomography, X-Ray Computed | 2013 |
Regulated forms of cell death are induced by the photodynamic action of the fluorogenic substrate, Hypocrellin B-acetate.
Topics: Apoptosis; Autophagy; Fluorescent Dyes; HeLa Cells; Humans; Light; Necrosis; Perylene; Phenol; Photosensitizing Agents; Quinones | 2013 |
Radioiodinated hypericin: its biodistribution, necrosis avidity and therapeutic efficacy are influenced by formulation.
Topics: Animals; Anthracenes; Antineoplastic Agents; Chemistry, Pharmaceutical; Dimethyl Sulfoxide; Iodine Radioisotopes; Liver; Male; Necrosis; Neoplasms; Perylene; Polyethylene Glycols; Radiopharmaceuticals; Rats; Spleen; Tissue Distribution; Water | 2014 |
In vivo molecular imaging of apoptosis and necrosis in atherosclerotic plaques using microSPECT-CT and microPET-CT imaging.
Topics: Animals; Annexin A5; Anthracenes; Apoptosis; Humans; Mice; Molecular Imaging; Multimodal Imaging; Necrosis; Perylene; Plaque, Atherosclerotic; Positron-Emission Tomography; Technetium; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 2014 |
Targetability and biodistribution of radioiodinated hypericin: comparison between microdosing and carrier-added preparations.
Topics: Animals; Anthracenes; Antineoplastic Agents; Chromatography, High Pressure Liquid; Drug Carriers; Fibrosarcoma; Iodine Radioisotopes; Liver; Male; Mice; Mice, SCID; Necrosis; Neoplasms, Experimental; Perylene; Rats; Rats, Wistar; Tissue Distribution | 2014 |
Improvement of solubility and targetability of radioiodinated hypericin by using sodium cholate based solvent in rat models of necrosis.
Topics: Animals; Anthracenes; Disease Models, Animal; Iodine Radioisotopes; Liver; Magnetic Resonance Imaging; Male; Muscle, Skeletal; Necrosis; Perylene; Rats, Sprague-Dawley; Sodium Cholate; Solubility; Solvents; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2014 |
Sodium cholate, a solubilizing agent for the necrosis avid radioiodinated hypericin in rabbits with acute myocardial infarction.
Topics: Animals; Anthracenes; Autoradiography; Disease Models, Animal; Gamma Cameras; Heart; Iodine Radioisotopes; Male; Microscopy, Fluorescence; Molecular Structure; Myocardial Infarction; Myocardium; Necrosis; Perylene; Rabbits; Radionuclide Imaging; Radiopharmaceuticals; Sodium Cholate; Solubility; Solutions; Tissue Distribution | 2015 |
Radiopharmaceutical study on Iodine-131-labelled hypericin in a canine model of hepatic RFA-induced coagulative necrosis.
Topics: Animals; Anthracenes; Catheter Ablation; Dogs; Liver; Male; Necrosis; Perylene; Radiopharmaceuticals; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2015 |
Effect of PKCα expression on Bcl-2 phosphorylation and cell death by hypericin.
Topics: Anthracenes; Apoptosis; Cell Line, Tumor; Cell Survival; Gene Expression; Humans; Mitochondria; Necrosis; Perylene; Phosphorylation; Photosensitizing Agents; Protein Kinase C-alpha; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Serine | 2014 |
Evaluation of hypericin: effect of aggregation on targeting biodistribution.
Topics: Animals; Anthracenes; Antineoplastic Agents, Phytogenic; Autoradiography; Dimethyl Sulfoxide; Drug Compounding; Drug Stability; Hydrophobic and Hydrophilic Interactions; Infarction; Iodine Radioisotopes; Liver; Liver Cirrhosis, Experimental; Male; Necrosis; Perylene; Pharmaceutical Vehicles; Radionuclide Imaging; Rats, Sprague-Dawley; Solubility; Tissue Distribution; Whole Body Imaging | 2015 |
Biodistribution and anti-tumor efficacy of intratumorally injected necrosis-avid theranostic agent radioiodinated hypericin in rodent tumor models.
Topics: Animals; Anthracenes; Antineoplastic Agents; Autoradiography; Carcinoma, Hepatocellular; Cell Line, Tumor; Injections, Intralesional; Iodine Radioisotopes; Liver Neoplasms; Mice; Microscopy, Fluorescence; Necrosis; Perylene; Rats; Sarcoma; Theranostic Nanomedicine; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2015 |
Radiopharmaceutical evaluation of (131)I-protohypericin as a necrosis avid compound.
Topics: Animals; Autoradiography; Disease Models, Animal; Half-Life; Infarction; Iodine Radioisotopes; Liver; Male; Necrosis; Perylene; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2015 |
Necrosis targeted radiotherapy with iodine-131-labeled hypericin to improve anticancer efficacy of vascular disrupting treatment in rabbit VX2 tumor models.
Topics: Animals; Anthracenes; Autoradiography; Disease Models, Animal; Iodine Radioisotopes; Necrosis; Neoplasms; Neovascularization, Pathologic; Perylene; Rabbits; Radiopharmaceuticals; Random Allocation; Tomography, Emission-Computed, Single-Photon | 2015 |
Tumor necrosis targeted radiotherapy of non-small cell lung cancer using radioiodinated protohypericin in a mouse model.
Topics: Animals; Antineoplastic Agents; Autoradiography; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Chemoradiotherapy; Disease Models, Animal; Humans; Iodine Radioisotopes; Lung Neoplasms; Magnetic Resonance Imaging; Male; Mice, Inbred BALB C; Mice, Nude; Necrosis; Perylene; Radiography; Radiopharmaceuticals; Stilbenes; Tissue Distribution; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Synthesis and Preclinical Evaluation of Radioiodinated Hypericin Dicarboxylic Acid as a Necrosis Avid Agent in Rat Models of Induced Hepatic, Muscular, and Myocardial Necroses.
Topics: Animals; Anthracenes; Iodine Radioisotopes; Liver; Muscle, Skeletal; Myocardial Infarction; Myocardium; Necrosis; Perylene; Rats; Tomography, Emission-Computed, Single-Photon | 2016 |
Effects of skeleton structure on necrosis targeting and clearance properties of radioiodinated dianthrones.
Topics: Animals; Anthracenes; Cell Line, Tumor; Disease Models, Animal; Drug Delivery Systems; Drug Design; Emodin; Humans; Hydrogen Peroxide; Iodine Radioisotopes; Lung Neoplasms; Male; Necrosis; Perylene; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2016 |
Discovery of Radioiodinated Monomeric Anthraquinones as a Novel Class of Necrosis Avid Agents for Early Imaging of Necrotic Myocardium.
Topics: Animals; Anthracenes; Anthraquinones; Chromatography, High Pressure Liquid; Iodine Radioisotopes; Male; Mice; Multimodal Imaging; Myocardial Infarction; Myocardium; Necrosis; Perylene; Radiochemistry; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 2016 |
Improved therapeutic outcomes of thermal ablation on rat orthotopic liver allograft sarcoma models by radioiodinated hypericin induced necrosis targeted radiotherapy.
Topics: Allografts; Animals; Anthracenes; Cell Line, Tumor; Combined Modality Therapy; Hyperthermia, Induced; Iodine Radioisotopes; Liver Neoplasms, Experimental; Male; Necrosis; Perylene; Radiation-Sensitizing Agents; Radiotherapy; Rats; Rats, Sprague-Dawley; Sarcoma; Treatment Outcome | 2016 |
Influence of the vascular damaging agents DMXAA and ZD6126 on hypericin distribution and accumulation in RIF-1 tumors.
Topics: Animals; Anthracenes; Antineoplastic Agents; Cell Line, Tumor; Mice; Mice, Inbred C3H; Necrosis; Neoplasms; Neovascularization, Pathologic; Organophosphorus Compounds; Perylene; Telomere-Binding Proteins; Xanthones | 2011 |
Radiolabeled iodohypericin as tumor necrosis avid tracer: diagnostic and therapeutic potential.
Topics: Animals; Anthracenes; Autoradiography; Female; Fibrosarcoma; Fluorodeoxyglucose F18; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Fluorescence; Necrosis; Neoplasms, Radiation-Induced; Perylene; Prognosis; Radionuclide Imaging; Random Allocation | 2012 |
Pretargeting of necrotic tumors with biotinylated hypericin using 123I-labeled avidin: evaluation of a two-step strategy.
Topics: Animals; Anthracenes; Antineoplastic Agents; Avidin; Biotin; Biotinylation; Cell Line, Tumor; Contrast Media; Ethanol; Female; Iodine Radioisotopes; Mice; Mice, Inbred C3H; Necrosis; Neoplasms; Perylene; Tissue Distribution | 2012 |
Hypericin-PDT-induced rapid necrotic death in human squamous cell carcinoma cultures after multiple treatment.
Topics: Anthracenes; Carcinoma, Squamous Cell; Cell Line, Tumor; Humans; Hypericum; Necrosis; Perylene; Photochemotherapy; Reactive Oxygen Species; Skin Neoplasms | 2012 |
Hypericin-mediated photodynamic therapy induces lipid peroxidation and necrosis in nasopharyngeal cancer.
Topics: Animals; Anthracenes; Antioxidants; Apoptosis; Cell Line, Tumor; Cytoplasm; Humans; Light; Lipid Peroxidation; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron; Nasopharyngeal Neoplasms; Necrosis; Neoplasm Transplantation; Oxygen; Perylene; Photochemotherapy; Reactive Oxygen Species; Superoxide Dismutase; Time Factors | 2003 |
Hypericin-photodynamic therapy (PDT) using an alternative treatment regime suitable for multi-fraction PDT.
Topics: Animals; Anthracenes; Apoptosis; Calcium; Immunohistochemistry; Light; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Atomic Force; Nasopharyngeal Neoplasms; Necrosis; Oxygen; Perylene; Photochemotherapy; Photosensitizing Agents; Time Factors; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Zinc | 2006 |
Anti-angiogenic effects of Hypericin-photodynamic therapy in combination with Celebrex in the treatment of human nasopharyngeal carcinoma.
Topics: Angiogenesis Inhibitors; Animals; Anthracenes; Celecoxib; Cyclooxygenase 2; Drug Therapy, Combination; Evans Blue; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Male; Mice; Mice, Inbred BALB C; Middle Aged; Nasopharyngeal Neoplasms; Necrosis; Neovascularization, Pathologic; Perylene; Photochemotherapy; Pyrazoles; RNA, Messenger; Sulfonamides; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2005 |
First preclinical evaluation of mono-[123I]iodohypericin as a necrosis-avid tracer agent.
Topics: Animals; Anthracenes; Drug Evaluation, Preclinical; Heart; Liver; Metabolic Clearance Rate; Myocardial Infarction; Myocardium; Necrosis; Perylene; Pilot Projects; Rabbits; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar; Tissue Distribution | 2006 |
Differential up-regulation of metallothionein isoforms in well-differentiated nasopharyngeal cancer cells in vitro by photoactivated hypericin.
Topics: Anthracenes; Flow Cytometry; Humans; In Vitro Techniques; Metallothionein; Nasopharyngeal Neoplasms; Necrosis; Perylene; Photochemotherapy; Photosensitizing Agents; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Up-Regulation | 2006 |
Synthesis and preliminary evaluation of mono-[123I]iodohypericin monocarboxylic acid as a necrosis avid imaging agent.
Topics: Animals; Autoradiography; Chromatography, High Pressure Liquid; Iodine Radioisotopes; Magnetic Resonance Spectroscopy; Mice; Necrosis; Perylene; Radionuclide Imaging; Rats | 2007 |
Necrosis predominates in the cell death of human colon adenocarcinoma HT-29 cells treated under variable conditions of photodynamic therapy with hypericin.
Topics: Adenocarcinoma; Anthracenes; Caspase 3; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Dose-Response Relationship, Radiation; Gene Expression; HeLa Cells; HT29 Cells; Humans; Light; Necrosis; Perylene; Photochemotherapy; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53 | 2007 |
Hypericin as a marker for determination of tissue viability after intratumoral ethanol injection in a murine liver tumor model.
Topics: Analysis of Variance; Animals; Anthracenes; Antineoplastic Agents; Disease Models, Animal; Ethanol; Female; Fibrosarcoma; Injections, Intralesional; Liver Neoplasms; Mice; Microscopy, Fluorescence; Necrosis; Neoplasm Transplantation; Perylene | 2008 |
Non-invasive detection and quantification of acute myocardial infarction in rabbits using mono-[123I]iodohypericin microSPECT.
Topics: Animals; Anthracenes; Disease Models, Animal; Drug Evaluation, Preclinical; Heart; Iodine Radioisotopes; Male; Myocardial Infarction; Necrosis; Perylene; Rabbits; Radiopharmaceuticals; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2008 |
Hypericin phototoxicity induces different modes of cell death in melanoma and human skin cells.
Topics: Anthracenes; Apoptosis; Caspase 3; Caspase 7; Cell Death; Cell Line, Tumor; Cell Survival; Humans; Intracellular Space; Keratinocytes; Melanocytes; Melanoma; Necrosis; Perylene; Photochemotherapy; Photosensitizing Agents; Skin | 2008 |
Exploration of the mechanism underlying the tumor necrosis avidity of hypericin.
Topics: Animals; Anthracenes; Carbocyanines; Female; Fibrosarcoma; Lipoproteins; Mice; Mice, Inbred C3H; Necrosis; Perylene; Sarcoma, Experimental; Xanthones | 2008 |
Hypericin as a marker for determination of tissue viability after radiofrequency ablation in a murine liver tumor model.
Topics: Animals; Anthracenes; Biomarkers; Catheter Ablation; Female; Liver Neoplasms, Experimental; Mice; Mice, Inbred C3H; Microscopy, Fluorescence; Necrosis; Perylene | 2008 |
Hypericin-induced photosensitization of HeLa cells leads to apoptosis or necrosis. Involvement of cytochrome c and procaspase-3 activation in the mechanism of apoptosis.
Topics: Amino Acid Chloromethyl Ketones; Anthracenes; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cell Nucleus; Cell Size; Cell Survival; Cysteine Proteinase Inhibitors; Cytochrome c Group; Cytosol; DNA Fragmentation; Enzyme Activation; Enzyme Precursors; HeLa Cells; Humans; Light; Necrosis; Oligopeptides; Perylene; Photosensitizing Agents; Poly(ADP-ribose) Polymerases; Serpins; Viral Proteins | 1998 |
A photodynamic pathway to apoptosis and necrosis induced by dimethyl tetrahydroxyhelianthrone and hypericin in leukaemic cells: possible relevance to photodynamic therapy.
Topics: Anthracenes; Apoptosis; bcl-2-Associated X Protein; Cell Nucleus; DNA, Neoplasm; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Genes, bcl-1; Genes, bcl-2; HL-60 Cells; Humans; Necrosis; Perylene; Photochemotherapy; Photosensitizing Agents; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Radiation-Sensitizing Agents | 1999 |
Hypocrellin and hypericin-induced phototoxicity of HL-60 cells: apoptosis or necrosis?
Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Drugs, Chinese Herbal; HL-60 Cells; Humans; Necrosis; Perylene; Phenol; Photosensitizing Agents; Quinones | 2000 |
Photo-activation of hypericin with low doses of light promotes apparent photo-resistance in human histiocytic lymphoma U937 cells.
Topics: Anthracenes; Apoptosis; Cell Death; Dose-Response Relationship, Radiation; Drug Resistance, Neoplasm; HSP70 Heat-Shock Proteins; Humans; Necrosis; Perylene; Phototherapy; Radiation Injuries; U937 Cells | 2001 |
Molecular aspects of photodynamic therapy: low energy pre-sensitization of hypericin-loaded human endometrial carcinoma cells enhances photo-tolerance, alters gene expression and affects the cell cycle.
Topics: Anthracenes; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Biological Transport; Carcinoma; Endometrial Neoplasms; Female; Gene Expression Regulation, Neoplastic; HSP70 Heat-Shock Proteins; Humans; Necrosis; Perylene; Photochemotherapy; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Radiation-Sensitizing Agents | 2002 |