Page last updated: 2024-08-20

perylene and Disease Models, Animal

perylene has been researched along with Disease Models, Animal in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (4.65)18.2507
2000's17 (39.53)29.6817
2010's22 (51.16)24.3611
2020's2 (4.65)2.80

Authors

AuthorsStudies
Bai, M; Bao, Y; Huang, Y; Li, Y; Liang, C; Liu, L; Song, Z; Sun, L; Wang, S; Yang, H; Yi, J; Yu, C1
Araújo, VHS; Bauab, TM; Calixto, GMF; Chorilli, M; de Araújo, PR; Oshiro-Junior, JA; Rodero, CF; Sato, MR1
Busch, C; Cheng, PF; Garbe, C; Ikenberg, K; Krochmann, J; Levesque, MP; Meraz-Torres, F; Niessner, H; Sinnberg, T1
Corbi, ST; de Oliveira, GJPL; Macedo, PD; Marcantonio, RAC; Perussi, JR; Ribeiro, AO1
Babinčák, M; Buríková, M; Fedoročko, P; Jendželovská, Z; Jendželovský, R; Košuth, J; Majerník, M; Ševc, J; Tonelli Gombalová, Z1
Chen, F; Cona, MM; de Witte, P; Feng, Y; Li, J; Ni, Y; Nuyts, J; Oyen, R; Verbruggen, A; Yu, J; Zhang, G; Zhang, J; Zhou, L1
Chen, F; Cona, MM; Feng, Y; Gheysens, O; Li, Y; Ni, Y; Nuyts, J; Oyen, R; Rezaei, A; Van Slambrouck, K; Verbruggen, A; Vunckx, K; Zhou, L1
Asem, H; El-Gowelli, H; Kandil, S; Nafee, N; Youssef, A1
Darcha, C; Matsuzaki, S1
Ehrhardt, A; Feigl, GC; Göbel, W; Mayer, D; Naumann, U; Noell, S; Ritz, R; Serifi, D1
Cona, MM; Fang, Z; Gao, M; Ji, Y; Jiang, C; Jiang, X; Li, Y; Liu, W; Ni, Y; Sun, Z; Wang, J; Wang, Q; Wang, X; Yao, N; Yin, Z; Zhan, Y; Zhang, J1
Birt, DF; Hammer, KD1
Cona, MM; Feng, Y; Li, Y; Ni, Y; Oyen, R; Verbruggen, A; Zhang, J1
Dai, K; Fan, Q; Li, H; Li, X; Liu, X; Ouyang, Z; Qin, A; Qu, X; Tang, T; Zhai, Z1
Feng, Y; Gao, M; Huang, D; Ji, Y; Jiang, C; Li, Y; Liu, W; Liu, X; Lou, B; Ni, Y; Sun, Z; Wang, Q; Yao, N; Yin, Z; Zhang, J1
Chen, H; Deng, H; Gu, Y; Hou, X; Huang, N; Li, T; Zeng, J; Zhao, J1
Chen, C; Chen, F; Lu, YN; Zhai, XJ; Zhu, CR1
Chen, F; Dai, X; Li, Y; Ni, Y; Shao, H; Sun, Z; Xu, K; Zhang, J1
Gao, M; Huang, D; Jiang, C; Liu, X; Ni, Y; Peng, F; Sun, Z; Yin, Z; Zhang, D; Zhang, J1
Feng, Y; Gao, M; Huang, D; Jiang, C; Ni, Y; Shao, H; Sun, Z; Wang, X; Yang, S; Yin, Z; Zhang, D; Zhang, J1
Huang, M; Ma, X; Xiong, M; Xu, C; Yang, J; Yang, X; Zhang, TC; Zhao, P; Zheng, S; Zhou, Q1
Delie, F; Gurny, R; Lange, N; Zeisser-Labouèbe, M1
Bai, J; Sun, F; Wang, D; Yang, D1
Bartolini, A; Bergonzi, MC; Bilia, AR; Galeotti, N; Ghelardini, C; Vivoli, E1
Boiy, A; de Witte, PA; Roelandts, R1
Chen, B; de Witte, PA; Roskams, T2
Ahmed, B; Chen, B; de Witte, PA; Gaspar, R; Landuyt, W; Ni, Y; Roskams, T1
Gobbi, M; Mennini, T1
Blank, M; Hazan, S; Keisari, Y; Lavie, G; Mandel, M; Meruelo, D; Orenstein, A1
Cheng, C; Chin, W; Lau, W; Olivo, M1
Barliya, T; Blank, M; Grunbaum, A; Hazan, S; Lavie, G; Mandel, M; Meruelo, D; Solomon, A1
Chen, TC; Gupta, V; Hofman, FM; Kardosh, A; Liebes, LF; Schönthal, AH; Su, YS; Wang, W1
Bobrov, N; Brezáni, P; Cavarga, I; Fedorocko, P; Longauer, F; Mirossay, L; Miskovský, P; Rybárová, S; Stubna, J1
Dobrić, S; Savikin, K; Tadić, V; Zdunić, G1
Butterweck, V; Schmidt, M1
Chen, F; de Witte, PA; Ni, Y; Van de Putte, M; Wang, H1
Bormans, G; Feng, Y; Fonge, H; Mortelmans, L; Ni, Y; Nuyts, J; Verbruggen, A; Vunckx, K; Wang, H1
Higuchi, A; Jo, N; Matsumura, M; Yamada, E; Yamada, H1
al-Sultan, II; Kako, MD; Saleem, AN1
Hinton, DR; Inomata, HR; Ishibashi, TR; Murata, TR; Oshima, YR; Ryan, SJ; Sakamoto, TR; Tahara, YR1
Chen, B; de Witte, PA1
Agostinis, P; Chen, B; de Witte, P; Delaey, E; Roskams, T; Vandenheede, JR; Xu, Y1

Reviews

3 review(s) available for perylene and Disease Models, Animal

ArticleYear
Evidence for contributions of interactions of constituents to the anti-inflammatory activity of Hypericum perforatum.
    Critical reviews in food science and nutrition, 2014, Volume: 54, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Biflavonoids; Disease Models, Animal; Flavonoids; Humans; Hypericum; Perylene; Phloroglucinol; Plant Extracts; Signal Transduction; Terpenes

2014
The antidepressant mechanism of Hypericum perforatum.
    Life sciences, 2004, Jul-16, Volume: 75, Issue:9

    Topics: Animals; Anthracenes; Bridged Bicyclo Compounds; Depression; Disease Models, Animal; Hypericum; Neurotransmitter Agents; Perylene; Phloroglucinol; Phytotherapy; Plant Extracts; Rats; Receptors, Dopamine D1; Receptors, Opioid; Terpenes

2004
St. John's wort: role of active compounds for its mechanism of action and efficacy.
    Wiener medizinische Wochenschrift (1946), 2007, Volume: 157, Issue:13-14

    Topics: Animals; Anthracenes; Antidepressive Agents; Bridged Bicyclo Compounds; Cells, Cultured; Clinical Trials as Topic; Disease Models, Animal; Humans; Hypericum; Ice; Meta-Analysis as Topic; Perylene; Phloroglucinol; Phytotherapy; Plant Extracts; Terpenes

2007

Other Studies

40 other study(ies) available for perylene and Disease Models, Animal

ArticleYear
Hypericin attenuates nonalcoholic fatty liver disease and abnormal lipid metabolism via the PKA-mediated AMPK signaling pathway in vitro and in vivo.
    Pharmacological research, 2020, Volume: 153

    Topics: AMP-Activated Protein Kinases; Animals; Anthracenes; Apoptosis; Cell Differentiation; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Hep G2 Cells; Hepatocytes; Humans; Lipid Metabolism; Male; Mesenchymal Stem Cells; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Perylene; Reactive Oxygen Species

2020
In vivo study of hypericin-loaded poloxamer-based mucoadhesive in situ gelling liquid crystalline precursor system in a mice model of vulvovaginal candidiasis.
    Medical mycology, 2021, Jul-14, Volume: 59, Issue:8

    Topics: Adhesives; Animals; Anthracenes; Antifungal Agents; Candida albicans; Candidiasis, Vulvovaginal; Chromatography, High Pressure Liquid; Disease Models, Animal; Female; Mice; Mice, Inbred C57BL; Microscopy, Polarization; Mucous Membrane; Perylene; Poloxamer; Radiation-Sensitizing Agents; Scattering, Small Angle; Swine; Vagina; X-Ray Diffraction

2021
Wnt-signaling enhances neural crest migration of melanoma cells and induces an invasive phenotype.
    Molecular cancer, 2018, 02-17, Volume: 17, Issue:1

    Topics: Animals; beta Catenin; Biomarkers; Cell Adhesion; Cell Movement; Cell Transformation, Neoplastic; Chick Embryo; Disease Models, Animal; Epithelial-Mesenchymal Transition; Gene Knockdown Techniques; Humans; Melanoma; Melanoma, Experimental; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Neural Crest; Perylene; Phenotype; RNA, Small Interfering; Wnt Signaling Pathway; Zebrafish

2018
Hypericin-glucamine antimicrobial photodynamic therapy in the progression of experimentally induced periodontal disease in rats.
    Photodiagnosis and photodynamic therapy, 2019, Volume: 25

    Topics: Animals; Anthracenes; Disease Models, Animal; Disease Progression; Male; Maxilla; Molar; Periodontal Diseases; Perylene; Photochemotherapy; Photosensitizing Agents; Random Allocation; Rats; Tomography, X-Ray Computed

2019
Novel Insights into the Effect of Hyperforin and Photodynamic Therapy with Hypericin on Chosen Angiogenic Factors in Colorectal Micro-Tumors Created on Chorioallantoic Membrane.
    International journal of molecular sciences, 2019, Jun-19, Volume: 20, Issue:12

    Topics: Angiogenesis Inducing Agents; Animals; Anthracenes; Biomarkers; Cell Line, Tumor; Chick Embryo; Chorioallantoic Membrane; Colorectal Neoplasms; Disease Models, Animal; Gene Expression; Humans; Neovascularization, Pathologic; Perylene; Phloroglucinol; Photochemotherapy; Photosensitizing Agents; Terpenes

2019
Sequential systemic administrations of combretastatin A4 Phosphate and radioiodinated hypericin exert synergistic targeted theranostic effects with prolonged survival on SCID mice carrying bifocal tumor xenografts.
    Theranostics, 2013, Volume: 3, Issue:2

    Topics: Administration, Intravenous; Animals; Anthracenes; Antineoplastic Agents; Disease Models, Animal; Fibrosarcoma; Histocytochemistry; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Mice; Mice, SCID; Perylene; Radiography; Radionuclide Imaging; Stilbenes; Survival Analysis; Transplantation, Heterologous; Treatment Outcome

2013
Comparative study of iodine-123-labeled hypericin and (99m)Tc-labeled hexakis [2-methoxy isobutyl isonitrile] in a rabbit model of myocardial infarction.
    Journal of cardiovascular pharmacology, 2013, Volume: 62, Issue:3

    Topics: Animals; Anthracenes; Autoradiography; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Gamma Cameras; Half-Life; Heart; Iodine Radioisotopes; Male; Myocardial Infarction; Myocardium; Necrosis; Perylene; Rabbits; Radionuclide Imaging; Radiopharmaceuticals; Technetium; Technetium Tc 99m Sestamibi; Tissue Distribution; Tomography, X-Ray Computed

2013
Antibiotic-free nanotherapeutics: hypericin nanoparticles thereof for improved in vitro and in vivo antimicrobial photodynamic therapy and wound healing.
    International journal of pharmaceutics, 2013, Sep-15, Volume: 454, Issue:1

    Topics: Animals; Anthracenes; Biofilms; Chemistry, Pharmaceutical; Disease Models, Animal; Female; Inflammation Mediators; Intercellular Signaling Peptides and Proteins; Methicillin-Resistant Staphylococcus aureus; Nanomedicine; Nanoparticles; Particle Size; Perylene; Photochemotherapy; Photosensitizing Agents; Polyesters; Polyethylene Glycols; Rats; Rats, Wistar; Reactive Oxygen Species; Technology, Pharmaceutical; Time Factors; Wound Healing; Wound Infection

2013
Involvement of the Wnt/β-catenin signaling pathway in the cellular and molecular mechanisms of fibrosis in endometriosis.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Actins; Adult; Animals; beta Catenin; Collagen; Connective Tissue Growth Factor; Disease Models, Animal; Endometriosis; Female; Fibrosis; Heterografts; Humans; Perylene; RNA Interference; Stromal Cells; Wnt Proteins; Wnt Signaling Pathway; Young Adult

2013
Microendoscopy for hypericin fluorescence tumor diagnosis in a subcutaneous glioma mouse model.
    Photodiagnosis and photodynamic therapy, 2013, Volume: 10, Issue:4

    Topics: Animals; Anthracenes; Brain Neoplasms; Cell Line, Tumor; Disease Models, Animal; Endoscopy; Glioma; Metabolic Clearance Rate; Mice; Perylene; Photosensitizing Agents; Reproducibility of Results; Sensitivity and Specificity; Skin Neoplasms; Spectrometry, Fluorescence; Tissue Distribution

2013
Improvement of solubility and targetability of radioiodinated hypericin by using sodium cholate based solvent in rat models of necrosis.
    Journal of drug targeting, 2014, Volume: 22, Issue:4

    Topics: Animals; Anthracenes; Disease Models, Animal; Iodine Radioisotopes; Liver; Magnetic Resonance Imaging; Male; Muscle, Skeletal; Necrosis; Perylene; Rats, Sprague-Dawley; Sodium Cholate; Solubility; Solvents; Tissue Distribution; Tomography, Emission-Computed, Single-Photon

2014
Sodium cholate, a solubilizing agent for the necrosis avid radioiodinated hypericin in rabbits with acute myocardial infarction.
    Drug delivery, 2015, Volume: 22, Issue:3

    Topics: Animals; Anthracenes; Autoradiography; Disease Models, Animal; Gamma Cameras; Heart; Iodine Radioisotopes; Male; Microscopy, Fluorescence; Molecular Structure; Myocardial Infarction; Myocardium; Necrosis; Perylene; Rabbits; Radionuclide Imaging; Radiopharmaceuticals; Sodium Cholate; Solubility; Solutions; Tissue Distribution

2015
Hypericin suppresses osteoclast formation and wear particle-induced osteolysis via modulating ERK signalling pathway.
    Biochemical pharmacology, 2014, Aug-01, Volume: 90, Issue:3

    Topics: Animals; Anthracenes; Bone Density Conservation Agents; Cell Line, Transformed; Cell Survival; Cell Transdifferentiation; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Macrophages; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Osteoclasts; Osteolysis; Perylene; Prosthesis Failure; Random Allocation; RANK Ligand; Recombinant Proteins; Skull

2014
Radiopharmaceutical evaluation of (131)I-protohypericin as a necrosis avid compound.
    Journal of drug targeting, 2015, Volume: 23, Issue:5

    Topics: Animals; Autoradiography; Disease Models, Animal; Half-Life; Infarction; Iodine Radioisotopes; Liver; Male; Necrosis; Perylene; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tomography, Emission-Computed, Single-Photon

2015
Liposomal hypocrellin B as a potential photosensitizer for age-related macular degeneration: pharmacokinetics, photodynamic efficacy, and skin phototoxicity in vivo.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2015, Volume: 14, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Choroidal Neovascularization; Disease Models, Animal; Drug Evaluation, Preclinical; Ear; Endothelial Cells; Female; Liposomes; Lung; Male; Mice; Microvessels; Organ Size; Perylene; Photochemotherapy; Photosensitizing Agents; Quinones; Rats; Retina; Skin; Wet Macular Degeneration

2015
LC-MS/MS based studies on the anti-depressant effect of hypericin in the chronic unpredictable mild stress rat model.
    Journal of ethnopharmacology, 2015, Jul-01, Volume: 169

    Topics: Amino Acids; Animals; Anthracenes; Antidepressive Agents; Behavior, Animal; Chromatography, Liquid; Corticosterone; Depression; Disease Models, Animal; Male; Neurotransmitter Agents; Perylene; Rats; Stress, Psychological; Tandem Mass Spectrometry; Venlafaxine Hydrochloride

2015
Necrosis targeted radiotherapy with iodine-131-labeled hypericin to improve anticancer efficacy of vascular disrupting treatment in rabbit VX2 tumor models.
    Oncotarget, 2015, Jun-10, Volume: 6, Issue:16

    Topics: Animals; Anthracenes; Autoradiography; Disease Models, Animal; Iodine Radioisotopes; Necrosis; Neoplasms; Neovascularization, Pathologic; Perylene; Rabbits; Radiopharmaceuticals; Random Allocation; Tomography, Emission-Computed, Single-Photon

2015
Tumor necrosis targeted radiotherapy of non-small cell lung cancer using radioiodinated protohypericin in a mouse model.
    Oncotarget, 2015, Sep-22, Volume: 6, Issue:28

    Topics: Animals; Antineoplastic Agents; Autoradiography; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Chemoradiotherapy; Disease Models, Animal; Humans; Iodine Radioisotopes; Lung Neoplasms; Magnetic Resonance Imaging; Male; Mice, Inbred BALB C; Mice, Nude; Necrosis; Perylene; Radiography; Radiopharmaceuticals; Stilbenes; Tissue Distribution; Tumor Burden; Xenograft Model Antitumor Assays

2015
Effects of skeleton structure on necrosis targeting and clearance properties of radioiodinated dianthrones.
    Journal of drug targeting, 2016, Volume: 24, Issue:6

    Topics: Animals; Anthracenes; Cell Line, Tumor; Disease Models, Animal; Drug Delivery Systems; Drug Design; Emodin; Humans; Hydrogen Peroxide; Iodine Radioisotopes; Lung Neoplasms; Male; Necrosis; Perylene; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Tissue Distribution

2016
Antidiabetic activity of perylenequinonoid-rich extract from Shiraia bambusicola in KK-Ay mice with spontaneous type 2 diabetes mellitus.
    Journal of ethnopharmacology, 2016, Sep-15, Volume: 191

    Topics: Acetates; Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Ascomycota; Biomarkers; Blood Glucose; Blotting, Western; Cell Line; Chromatography, Liquid; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin; Insulin Resistance; Lethal Dose 50; Lipids; Male; Myoblasts, Skeletal; Perylene; Phosphorylation; Protein Transport; Rats; Sasa; Signal Transduction; Solvents; Spectrometry, Mass, Electrospray Ionization; Time Factors

2016
Benefits of nanoencapsulation for the hypercin-mediated photodetection of ovarian micrometastases.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2009, Volume: 71, Issue:2

    Topics: Animals; Anthracenes; Disease Models, Animal; Drug Delivery Systems; Endoscopy; Female; Fluorescence; Injections, Intravenous; Lactic Acid; Nanoparticles; Neoplasm Metastasis; Ovarian Neoplasms; Perylene; Photosensitizing Agents; Polyesters; Polymers; Rats; Rats, Inbred F344; Tissue Distribution

2009
Chemical constituents and antidepressant activity of the new species Hypericum enshiense occurring in China.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Volume: 17, Issue:6

    Topics: Animals; Anthracenes; Antidepressive Agents; Behavior, Animal; China; Depression; Disease Models, Animal; Flavonoids; Hindlimb Suspension; Hypericum; Male; Mice; Mice, Inbred Strains; Motor Activity; Perylene; Phytotherapy; Plant Components, Aerial; Plant Extracts; Swimming

2010
A prolonged protein kinase C-mediated, opioid-related antinociceptive effect of st John's Wort in mice.
    The journal of pain, 2010, Volume: 11, Issue:2

    Topics: Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Anthracenes; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Compounding; Hypericum; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Perylene; Phorbol Esters; Phytotherapy; Protein Kinase C; Quercetin; Somatostatin; Spectrometry, Mass, Electrospray Ionization; Statistics, Nonparametric; Time Factors

2010
Photodynamic therapy using topically applied hypericin: comparative effect with methyl-aminolevulinic acid on UV induced skin tumours.
    Journal of photochemistry and photobiology. B, Biology, 2011, Feb-07, Volume: 102, Issue:2

    Topics: Administration, Topical; Aminolevulinic Acid; Animals; Anthracenes; Antineoplastic Agents; Disease Models, Animal; Female; Keratosis, Actinic; Mice; Mice, Hairless; Microscopy, Fluorescence; Perylene; Photochemotherapy; Photosensitizing Agents; Skin Neoplasms; Ultraviolet Rays

2011
Enhancing the antitumoral effect of hypericin-mediated photodynamic therapy by hyperthermia.
    Lasers in surgery and medicine, 2002, Volume: 31, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzimidazoles; Combined Modality Therapy; Disease Models, Animal; Female; Hyperthermia, Induced; In Situ Nick-End Labeling; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Perylene; Photochemotherapy; Staining and Labeling; Time Factors; Tumor Cells, Cultured

2002
Antivascular tumor eradication by hypericin-mediated photodynamic therapy.
    Photochemistry and photobiology, 2002, Volume: 76, Issue:5

    Topics: Animals; Anthracenes; Blood Vessels; Disease Models, Animal; Female; Laser Therapy; Mice; Mice, Inbred C3H; Perylene; Photochemotherapy; Photosensitizing Agents; Sarcoma, Experimental; Time Factors

2002
Potentiation of photodynamic therapy with hypericin by mitomycin C in the radiation-induced fibrosarcoma-1 mouse tumor model.
    Photochemistry and photobiology, 2003, Volume: 78, Issue:3

    Topics: Animals; Anthracenes; Disease Models, Animal; Drug Synergism; Female; Fibrosarcoma; Mice; Mitomycin; Perylene

2003
Antimetastatic activity of the photodynamic agent hypericin in the dark.
    International journal of cancer, 2004, Sep-10, Volume: 111, Issue:4

    Topics: Animals; Anthracenes; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Squamous Cell; Disease Models, Animal; Female; Humans; Light; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Perylene; Signal Transduction; Survival Analysis; Tissue Distribution

2004
Evaluation of Hypocrellin B in a human bladder tumor model in experimental photodynamic therapy: biodistribution, light dose and drug-light interval effects.
    International journal of oncology, 2004, Volume: 25, Issue:3

    Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Humans; Mice; Neoplasm Transplantation; Perylene; Photochemotherapy; Photosensitizing Agents; Quinones; Tissue Distribution; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays

2004
Anti-angiogenic activities of hypericin in vivo: potential for ophthalmologic applications.
    Angiogenesis, 2005, Volume: 8, Issue:1

    Topics: Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Animals; Anthracenes; Cornea; Corneal Neovascularization; Disease Models, Animal; Endothelium, Vascular; Extracellular Signal-Regulated MAP Kinases; Fibroblast Growth Factor 2; Genes, Tumor Suppressor; Humans; Iris; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Nuclear Proteins; Perylene; Phosphorylation; Rats; Rats, Wistar; Retinal Neovascularization; Vascular Endothelial Growth Factor A

2005
Enhancement of glioblastoma cell killing by combination treatment with temozolomide and tamoxifen or hypericin.
    Neurosurgical focus, 2006, Apr-15, Volume: 20, Issue:4

    Topics: Animals; Anthracenes; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Dacarbazine; Disease Models, Animal; Down-Regulation; Drug Synergism; Glioblastoma; Growth Inhibitors; Humans; Male; Mice; Mice, Nude; Perylene; Tamoxifen; Temozolomide; Transplantation, Heterologous; Treatment Outcome

2006
Histomorphological changes in murine fibrosarcoma after hypericin-based photodynamic therapy.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2007, Volume: 14, Issue:2-3

    Topics: Animals; Anthracenes; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Disease Models, Animal; Fibrosarcoma; Humans; Hypericum; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C3H; Perylene; Photochemotherapy; Photosensitizing Agents; Phytotherapy; Plant Extracts; Radiation Dosage

2007
Antiinflammatory activity of ethanol extracts of Hypericum perforatum L., H. barbatum Jacq., H. hirsutum L., H. richeri Vill. and H. androsaemum L. in rats.
    Phytotherapy research : PTR, 2007, Volume: 21, Issue:2

    Topics: Animals; Anthracenes; Anti-Inflammatory Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Hypericum; Indomethacin; Perylene; Plant Extracts; Rats

2007
Hypericin as a marker for determination of tissue viability after intratumoral ethanol injection in a murine liver tumor model.
    Academic radiology, 2008, Volume: 15, Issue:1

    Topics: Analysis of Variance; Animals; Anthracenes; Antineoplastic Agents; Disease Models, Animal; Ethanol; Female; Fibrosarcoma; Injections, Intralesional; Liver Neoplasms; Mice; Microscopy, Fluorescence; Necrosis; Neoplasm Transplantation; Perylene

2008
Non-invasive detection and quantification of acute myocardial infarction in rabbits using mono-[123I]iodohypericin microSPECT.
    European heart journal, 2008, Volume: 29, Issue:2

    Topics: Animals; Anthracenes; Disease Models, Animal; Drug Evaluation, Preclinical; Heart; Iodine Radioisotopes; Male; Myocardial Infarction; Necrosis; Perylene; Rabbits; Radiopharmaceuticals; Tissue Distribution; Tomography, Emission-Computed, Single-Photon

2008
Hypericin inhibits pathological retinal neovascularization in a mouse model of oxygen-induced retinopathy.
    Molecular vision, 2008, Feb-04, Volume: 14

    Topics: Angiogenesis Inhibitors; Animals; Anthracenes; Disease Models, Animal; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Hypericum; Ischemia; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Oxygen; Perylene; Phosphorylation; Retina; Retinal Diseases; Retinal Neovascularization

2008
Studies of sheep experimentally poisoned with Hypericum perforatum.
    Veterinary and human toxicology, 1993, Volume: 35, Issue:4

    Topics: Animals; Anthracenes; Disease Models, Animal; Enzymes; Hemodynamics; Perylene; Plant Poisoning; Plants, Toxic; Sheep; Sheep Diseases

1993
The antidepressant hypericin inhibits progression of experimental proliferative vitreoretinopathy.
    Current eye research, 1999, Volume: 19, Issue:4

    Topics: Animals; Anthracenes; Antidepressive Agents; Conjunctiva; Disease Models, Animal; Disease Progression; Electroretinography; Fibroblasts; Injections; Perylene; Protein Kinase C; Rabbits; Retina; Vitrectomy; Vitreoretinopathy, Proliferative

1999
Photodynamic therapy efficacy and tissue distribution of hypericin in a mouse P388 lymphoma tumor model.
    Cancer letters, 2000, Mar-13, Volume: 150, Issue:1

    Topics: Animals; Anthracenes; Antineoplastic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Injections, Intraperitoneal; Kidney; Liver; Mice; Mice, Inbred DBA; Muscles; Neoplasms, Experimental; Perylene; Photochemotherapy; Radiation-Sensitizing Agents; Skin; Spleen; Survival Analysis; Time Factors; Tissue Distribution; Treatment Outcome; Tumor Cells, Cultured

2000
Efficacy of antitumoral photodynamic therapy with hypericin: relationship between biodistribution and photodynamic effects in the RIF-1 mouse tumor model.
    International journal of cancer, 2001, Jul-15, Volume: 93, Issue:2

    Topics: Animals; Anthracenes; Antineoplastic Agents; Dermatitis, Phototoxic; Disease Models, Animal; Female; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Perylene; Photochemotherapy; Protein Binding; Skin; Time Factors; Tissue Distribution; Treatment Outcome; Tumor Cells, Cultured

2001