Compounds > perylene
Page last updated: 2024-08-20

perylene and Benign Neoplasms

perylene has been researched along with Benign Neoplasms in 73 studies

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (17.81)29.6817
2010's38 (52.05)24.3611
2020's22 (30.14)2.80

Authors

AuthorsStudies
Cao, J; Liu, X; Qi, X; Shen, S; Wu, L; Zhao, K1
Ling, G; Wang, Y; Xu, N; Zhang, P; Zhao, Z1
Ding, Y; Hong, L; Huang, F; Jin, L; Mao, Z; Sun, Z; Tong, Z; Wang, W; Yang, H; Ye, B; Zhou, J1
Li, Z; Liu, C; Qi, H; Ren, J; Song, S; Yang, N; Yu, C1
Chen, M; Duan, Y; Liang, R; Wong, KH; Yang, Y1
Hu, H; Wang, H; Xu, JF; Xue, KF; Yang, Y; Zhang, X1
Cui, Z; Huang, Y; Liu, Y; Lou, X; Wang, T; Zhang, B; Zhang, W; Zheng, R1
Huang, Y; Liu, Y; Liu, Z; Lou, X; Wang, H; Wang, T; Zhang, W1
Bakoshi, ABK; Balbinot, RB; Caetano, W; da Silva Junior, RC; da Silva Souza Campanholi, K; de Morais, FAP; de Oliveira Silva, S; Gonçalves, RS; Lazarin-Bidoia, D; Nakamura, CV; Ueda-Nakamura, T1
Almáši, M; Benziane, A; Girman, V; Huntošová, V; Miklóšová, M; Pevná, V; Vámosi, G; Zauška, Ľ; Zeleňák, V1
Arous, D; Berg, K; Brondz, E; Edin, NFJ; Görgen, A; Grigalavicius, M; Malinen, E; Mastrangelopoulou, M; Ménard, M; Raabe-Henriksen, T; Siem, S; Theodossiou, TA1
Astakhova, K; Taskova, M1
Liu, W; Wang, P; Wu, J; Zhang, C; Zheng, X1
Borghi-Pangoni, FB; Bruschi, ML; Junqueira, MV1
Chen, J; Dai, Y; Ke, Z; Shen, L; Xie, A; Zou, D; Zou, Z1
Farsad, K; Han, X; Jahangiri, Y; Moses, A; St Lorenz, A; Taratula, O; Xu, K; Yu, G1
Li, B; Li, F; Lu, C; Teng, X1
Li, H; Wu, F; Wu, M; Yue, L1
Beneš, J; Staničová, J; Verebová, V1
Gao, L; He, X; Huang, G; Jiang, X; Li, Y; Ni, Y; Wan, L; Wang, S; Wang, X; Zhao, H; Zhou, X; Zhou, Z1
Hong, J; Keum, C; Kim, D; Kim, H; Lee, SY1
Cruz, LJ; Dong, X; Fu, J; Gu, Z; Hao, Y; He, Y; Ni, J; Qu, C; Yin, X; You, L; Yu, Z; Zeng, Y; Zhang, Z1
Li, H; Li, L; Liu, G; Luo, X; Wu, F; Yue, L; Zhang, J1
Li, JM; Wang, KR1
Chen, X; Fan, Q; Huang, W; Jacobson, O; Liu, G; Niu, G; Song, J; Tian, R; Wang, Z; Wu, J; Yang, Z; Yu, G; Yung, BC1
Čulka, Ľ; Fedoročko, P; Fedr, R; Jendželovský, R; Kozubík, A; Kuchárová, B; Mikeš, J; Mikešová, L; Remšík, J; Souček, K; Vargová, J1
Chen, C; Geng, C; Hidru, TH; Li, H; Liu, Y; Tao, M; Zhang, Y; Zhi, L; Zou, L1
Ding, Y; Ge, J; Guo, L; Jia, Q; Liu, W; Wang, P; Wu, J; Zhang, H; Zheng, X1
Chen, X; Yang, Z1
Agostinis, P; Dudek, AM; Ferreira, GB; Garg, AD; Krysko, DV; Mathieu, C; Vandenabeele, P; Verfaillie, T1
Alpizar, YA; Bauwens, M; Chen, F; Cona, MM; de Witte, P; Feng, Y; Li, J; Ni, Y; Oyen, R; Sun, Z; Talavera, K; Verbruggen, A; Zhang, J1
Ge, X; Li, F; Liu, J; Shen, J; Wei, S; Zhou, J; Zhou, L1
Barras, A; Boukherroub, R; Boussekey, L; Courtade, E1
Gu, Z; Hu, Z; Jin, S; Liu, X; Ren, W; Tian, G; Yan, L; Yin, W; Zhang, X; Zhao, Y; Zhou, L1
Cona, MM; Feng, Y; Koole, M; Liu, Y; Ni, Y; Oyen, R; Verbruggen, A1
Agostinis, P; Garg, AD1
He, D; Liu, Q; Na, N; Ouyang, J; Yang, C; Zhao, Y1
Chen, BJ; Tanaka, Y; Wu, YL; Zhang, W1
Ge, X; Shen, J; Wei, S; Zhou, J; Zhou, L1
Cheng, W; Guo, K; Shen, J; Tang, J; Xu, Z; Yang, W; Yin, M; Yu, J1
Fedoročko, P; Jendželovská, Z; Jendželovský, R; Kovaľ, J; Kuchárová, B; Mikeš, J; Mikešová, L; Vargová, J1
Chen, F; Dai, X; Li, Y; Ni, Y; Shao, H; Sun, Z; Xu, K; Zhang, J1
Agostinis, P; de Witte, P; Elsen, S; Garg, AD; Krysko, DV; Vandenabeele, P1
Fei, J; Li, J; Qin, C; Wang, A; Yang, Y1
Cheng, Z; Deng, K; Deng, X; Hou, Z; Jin, D; Li, C; Lian, H; Lin, J1
Heng, PW; Olivo, M; Saw, CL1
Bilia, AR; Karioti, A1
Chen, J; Huang, M; Madiyalakan, R; Meng, Y; Swanson, E; Woo, T; Xing, JZ; Yang, X; Zou, C1
Chen, J; Chi, M; Ni, G1
de Witte, P; Lerut, E; Marysael, T; Ni, Y1
Barliya, T; Lavie, G; Livnat, T; Mandel, M; Weinberger, D1
Fu, CY; Lau, WK; Olivo, M; Raghavan, V1
Bauwens, M; Bormans, G; de Witte, P; Marysael, T; Ni, Y; Rozenski, J1
Agostinis, P; Garg, AD; Krysko, DV; Vandenabeele, P1
Krammer, B; Verwanger, T1
Devi, KS; Jana, A; Maiti, TK; Singh, ND1
Buzova, D; Huntosova, V; Jancura, D; Kasak, P; Miskovsky, P; Nadova, Z; Petrovajova, D; Sureau, F1
Isgor, BS; Isgor, YG; Keskin, T; Yukruk, F1
Ge, X; Shen, J; Wei, S; Yu, B; Zhou, J; Zhou, L1
Altieri, A; Alvino, A; Bianco, A; Biroccio, A; Casagrande, V; Ciammaichella, A; Franceschin, M; Iachettini, S; Leonetti, C; Ortaggi, G; Porru, M; Rizzo, A; Salvati, E1
Cui, W; Du, C; Fei, J; Gao, L; Li, J; Yang, Y; Zhao, J1
Ali, SM; Olivo, M3
Agostinis, P; Habraken, Y; Matroule, JY; Piette, J; Vantieghem, A; Volanti, C1
Chin, W; Lau, W; Lay, SL; Olivo, M; Wei, KK1
Alth, G; Burner, U; Grünberger, W; Kubin, A; Wierrani, F1
Chin, W; Olivo, M1
Kiesslich, T; Krammer, B; Plaetzer, K1
Agostinis, P; Buytaert, E; de Witte, P; Golab, J; Kocanova, S; Matroule, JY; Piette, J1
Chio-Srichan, S; Dumas, P; Jamme, F; Kascakova, S; Réfrégiers, M; Rouam, V1
Bearss, DJ; Hurley, LH; Von Hoff, DD1
Agostinis, P; de Witte, PA; Merlevede, W; Vantieghem, A1

Reviews

17 review(s) available for perylene and Benign Neoplasms

ArticleYear
Perylene diimide-based treatment and diagnosis of diseases.
    Journal of materials chemistry. B, 2021, 11-10, Volume: 9, Issue:43

    Topics: Antineoplastic Agents; Humans; Imides; Neoplasms; Particle Size; Perylene; Photoacoustic Techniques; Surface Properties

2021
Biophysical Characterization and Anticancer Activities of Photosensitive Phytoanthraquinones Represented by Hypericin and Its Model Compounds.
    Molecules (Basel, Switzerland), 2020, Dec-01, Volume: 25, Issue:23

    Topics: Animals; Anthracenes; Anthraquinones; Antineoplastic Agents; Humans; Neoplasms; Perylene; Photochemotherapy; Photosensitizing Agents

2020
Hypericin-mediated photodynamic therapy for the treatment of cancer: a review.
    The Journal of pharmacy and pharmacology, 2021, Mar-08, Volume: 73, Issue:4

    Topics: Anthracenes; Antineoplastic Agents; Humans; Molecular Targeted Therapy; Neoplasms; Perylene; Photochemotherapy; Photosensitizing Agents; Signal Transduction

2021
Sonodynamic therapy: A potential treatment for atherosclerosis.
    Life sciences, 2018, Aug-15, Volume: 207

    Topics: Animals; Anthracenes; Antineoplastic Agents; Apoptosis; Atherosclerosis; Berberine; Cell Death; Chalcone; Curcumin; Emodin; Humans; Inflammation; Macrophages; Matrix Metalloproteinases; Mice; Neoplasms; Perylene; Photochemotherapy; Plaque, Atherosclerotic; Quinones; Reactive Oxygen Species; THP-1 Cells; Ultrasonic Therapy

2018
ER stress, autophagy and immunogenic cell death in photodynamic therapy-induced anti-cancer immune responses.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2014, Volume: 13, Issue:3

    Topics: Animals; Anthracenes; Autophagy; Cell Death; Endoplasmic Reticulum Stress; Humans; Immune System Phenomena; Neoplasms; Perylene; Photochemotherapy; Photosensitizing Agents

2014
Small molecules targeting c-Myc oncogene: promising anti-cancer therapeutics.
    International journal of biological sciences, 2014, Volume: 10, Issue:10

    Topics: Alkaloids; Antineoplastic Agents; Apoptosis; Benzimidazoles; Benzoxazines; Cell Transformation, Neoplastic; Dimerization; Drug Discovery; G-Quadruplexes; Gene Components; Gene Expression Regulation, Neoplastic; Humans; Indoles; Ligands; Molecular Structure; Neoplasms; Perylene; Proto-Oncogene Proteins c-myc; Quinolines; Quinolones; Ribosomes

2014
Potentiation of the photodynamic action of hypericin.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2008, Volume: 27, Issue:1

    Topics: Adjuvants, Pharmaceutic; Animals; Anthracenes; Combined Modality Therapy; Humans; Neoplasms; Perylene; Photochemotherapy; Radiation-Sensitizing Agents

2008
Hypericins as potential leads for new therapeutics.
    International journal of molecular sciences, 2010, Feb-04, Volume: 11, Issue:2

    Topics: Anthracenes; Anti-Infective Agents; Antidepressive Agents; Cell Survival; Humans; Hypericum; Neoplasms; Perylene; Photochemotherapy; Photosensitizing Agents

2010
New frontier in hypericin-mediated diagnosis of cancer with current optical technologies.
    Annals of biomedical engineering, 2012, Volume: 40, Issue:2

    Topics: Anthracenes; Diagnostic Imaging; Fluorescence; Humans; Neoplasms; Perylene; Photochemotherapy; Photosensitizing Agents

2012
Molecular response to hypericin-induced photodamage.
    Current medicinal chemistry, 2012, Volume: 19, Issue:6

    Topics: Animals; Anthracenes; Antineoplastic Agents; Humans; Neoplasms; Perylene; Photochemotherapy; Photosensitizing Agents; Signal Transduction

2012
Mechanisms of action of phenanthroperylenequinones in photodynamic therapy (review).
    International journal of oncology, 2003, Volume: 22, Issue:6

    Topics: Apoptosis; Cell Death; Humans; Models, Biological; Neoplasms; Nitric Oxide; Perylene; Phenanthrenes; Photochemotherapy; Photosensitizing Agents; Phytotherapy; Quinones

2003
Cell death and growth arrest in response to photodynamic therapy with membrane-bound photosensitizers.
    Biochemical pharmacology, 2003, Oct-15, Volume: 66, Issue:8

    Topics: Animals; Anthracenes; Apoptosis; Cell Division; Humans; Mitochondria; Neoplasms; Perylene; Photochemotherapy; Photosensitizing Agents; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species

2003
Hypericin--the facts about a controversial agent.
    Current pharmaceutical design, 2005, Volume: 11, Issue:2

    Topics: Animals; Anthracenes; Austria; Cell Death; Humans; Molecular Structure; Neoplasms; Perylene; Photochemotherapy; Phytotherapy; Reproducibility of Results; Viruses

2005
Perylenequinones in photodynamic therapy: cellular versus vascular response.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2006, Volume: 25, Issue:1-2

    Topics: Animals; Anthracenes; Apoptosis; Blood Vessels; Humans; Neoplasms; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones

2006
Cellular mechanisms and prospective applications of hypericin in photodynamic therapy.
    Current medicinal chemistry, 2006, Volume: 13, Issue:18

    Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Mitochondria; Neoplasms; Neovascularization, Pathologic; Perylene; Photochemotherapy; Radiation-Sensitizing Agents; Signal Transduction

2006
Telomere maintenance mechanisms as a target for drug development.
    Oncogene, 2000, Dec-27, Volume: 19, Issue:56

    Topics: Animals; Anthracenes; Antineoplastic Agents; Drug Delivery Systems; Drug Design; Glycoside Hydrolases; Humans; Neoplasms; Oligonucleotides, Antisense; Perylene; Piperidines; Poly(ADP-ribose) Polymerases; Reverse Transcriptase Inhibitors; RNA; RNA, Long Noncoding; RNA, Untranslated; Tankyrases; Telomerase; Telomere

2000
Hypericin in cancer treatment: more light on the way.
    The international journal of biochemistry & cell biology, 2002, Volume: 34, Issue:3

    Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Cytochrome c Group; HeLa Cells; Humans; Hypericum; Microscopy, Fluorescence; Models, Biological; Molecular Structure; Neoplasms; Perylene; Photochemotherapy; Photosensitizing Agents; Proto-Oncogene Proteins c-bcl-2; Signal Transduction

2002

Other Studies

56 other study(ies) available for perylene and Benign Neoplasms

ArticleYear
Ultrasound responsive self-assembled micelles loaded with hypocrellin for cancer sonodynamic therapy.
    International journal of pharmaceutics, 2021, Oct-25, Volume: 608

    Topics: Cell Line, Tumor; Humans; Micelles; Nanoparticles; Neoplasms; Perylene; Phenol; Quinones; Reactive Oxygen Species

2021
An NIR Discrete Metallacycle Constructed from Perylene Bisimide and Tetraphenylethylene Fluorophores for Imaging-Guided Cancer Radio-Chemotherapy.
    Advanced materials (Deerfield Beach, Fla.), 2022, Volume: 34, Issue:7

    Topics: Animals; Cell Line, Tumor; Fluorescent Dyes; Imides; Mice; Nanoparticles; Neoplasms; Perylene; Stilbenes; Theranostic Nanomedicine

2022
Controlled Aggregation of a Perylene-Derived Probe for Near-Infrared Fluorescence Imaging and Phototherapy.
    ACS applied bio materials, 2021, 06-21, Volume: 4, Issue:6

    Topics: Animals; Cell Line, Tumor; Cell Survival; Embryo, Nonmammalian; Fluorescence; Fluorescent Dyes; Humans; Mice, Inbred BALB C; Microscopy, Confocal; Nanoparticles; Neoplasms; Optical Imaging; Perylene; Photochemotherapy; Photosensitizing Agents; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Superoxides; Zebrafish

2021
ROS-responsive dexamethasone micelles normalize the tumor microenvironment enhancing hypericin in cancer photodynamic therapy.
    Biomaterials science, 2022, Feb-15, Volume: 10, Issue:4

    Topics: Anthracenes; Cell Line, Tumor; Dexamethasone; Endothelial Cells; Micelles; Neoplasms; Perylene; Photochemotherapy; Photosensitizing Agents; Reactive Oxygen Species; Tumor Microenvironment; Vascular Endothelial Growth Factor A

2022
In Situ Hypoxia-Induced Supramolecular Perylene Diimide Radical Anions in Tumors for Photothermal Therapy with Improved Specificity.
    Journal of the American Chemical Society, 2022, 02-09, Volume: 144, Issue:5

    Topics: Animals; Anions; HeLa Cells; Humans; Macromolecular Substances; Mice; Mice, Nude; Neoplasms; Neoplasms, Experimental; Oxygen; Perylene; Photothermal Therapy

2022
Perylene-Mediated Electron Leakage in Respiratory Chain to Trigger Endogenous ROS Burst for Hypoxic Cancer Chemo-Immunotherapy.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:3

    Topics: Electron Transport; Electrons; Humans; Hypoxia; Immunotherapy; Neoplasms; Perylene; Reactive Oxygen Species; Tumor Microenvironment

2023
Perylene-Based Reactive Oxygen Species Supergenerator for Immunogenic Photochemotherapy against Hypoxic Tumors.
    Angewandte Chemie (International ed. in English), 2023, 03-06, Volume: 62, Issue:11

    Topics: Cell Line, Tumor; Humans; Hypoxia; Infrared Rays; Nanoparticles; Neoplasms; Oxygen; Perylene; Photochemotherapy; Photosensitizing Agents; Reactive Oxygen Species

2023
Advanced theranostic nanoplatforms for hypericin delivery in the cancer treatment.
    Journal of photochemistry and photobiology. B, Biology, 2023, Volume: 247

    Topics: Anthracenes; Caco-2 Cells; Humans; Lipids; Neoplasms; Perylene; Photochemotherapy; Polymers; Precision Medicine; Tissue Distribution

2023
Effective transport of aggregated hypericin encapsulated in SBA-15 nanoporous silica particles for photodynamic therapy of cancer cells.
    Journal of photochemistry and photobiology. B, Biology, 2023, Volume: 247

    Topics: Anthracenes; Nanopores; Neoplasms; Perylene; Photochemotherapy; Photosensitizing Agents; Silicon Dioxide

2023
Proton-dynamic therapy following photosensitiser activation by accelerated protons demonstrated through fluorescence and singlet oxygen production.
    Nature communications, 2019, 09-04, Volume: 10, Issue:1

    Topics: Cell Death; Cell Line, Tumor; Chemoradiotherapy; Fluorescence; Humans; Neoplasms; Perylene; Photosensitizing Agents; Piperazines; Proton Therapy; Protons; Protoporphyrins; Radiation-Protective Agents; Singlet Oxygen; Spectrometry, Fluorescence

2019
Solid-Phase Hybridization Assay for Detection of Mutated Cancer DNA by Fluorescence.
    Methods in molecular biology (Clifton, N.J.), 2020, Volume: 2063

    Topics: DNA; ErbB Receptors; Fluorescence; Fluorescent Dyes; Fluorometry; Humans; Limit of Detection; Neoplasms; Nucleic Acid Hybridization; Perylene; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins B-raf

2020
Natural-Origin Hypocrellin-HSA Assembly for Highly Efficient NIR Light-Responsive Phototheranostics against Hypoxic Tumors.
    ACS applied materials & interfaces, 2019, Dec-04, Volume: 11, Issue:48

    Topics: Animals; Cell Line, Tumor; Female; Humans; Hyperthermia, Induced; Infrared Rays; Mice; Mice, Nude; Nanoparticles; Neoplasms; Perylene; Phenol; Photochemotherapy; Quinones; Serum Albumin; Theranostic Nanomedicine

2019
Physicochemical stability of bioadhesive thermoresponsive platforms for methylene blue and hypericin delivery in photodynamic therapy.
    Pharmaceutical development and technology, 2020, Volume: 25, Issue:4

    Topics: Acrylates; Adhesives; Anthracenes; Delayed-Action Preparations; Drug Delivery Systems; Drug Liberation; Drug Stability; Humans; Methylene Blue; Neoplasms; Perylene; Photochemotherapy; Photosensitizing Agents; Poloxamer; Temperature

2020
Naturally available hypericin undergoes electron transfer for type I photodynamic and photothermal synergistic therapy.
    Biomaterials science, 2020, May-06, Volume: 8, Issue:9

    Topics: Animals; Anthracenes; Antineoplastic Agents; Cell Line, Tumor; Electrons; Female; HeLa Cells; Humans; Lasers; Male; Mice, Nude; Nanoparticles; Neoplasms; Perylene; Phosphatidylethanolamines; Photochemotherapy; Photothermal Therapy; Polyethylene Glycols; Radiation-Sensitizing Agents; Rats, Sprague-Dawley; Tumor Burden

2020
Biodegradable Hypericin-Containing Nanoparticles for Necrosis Targeting and Fluorescence Imaging.
    Molecular pharmaceutics, 2020, 05-04, Volume: 17, Issue:5

    Topics: Animals; Anthracenes; Cell Line, Tumor; Female; Humans; Mice; Nanoparticles; Necrosis; Neoplasms; Optical Imaging; Perylene

2020
Carbon dot-assisted luminescence of singlet oxygen: the generation dynamics but not the cumulative amount of singlet oxygen is responsible for the photodynamic therapy efficacy.
    Nanoscale horizons, 2020, 06-01, Volume: 5, Issue:6

    Topics: Animals; Anthracenes; Antineoplastic Agents; Carbon; Female; HeLa Cells; Humans; Imidazoles; Luminescence; Luminescent Agents; Methylene Blue; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Perylene; Photochemotherapy; Photosensitizing Agents; Quantum Dots; Quinones; Singlet Oxygen

2020
Self-assembly of methylene violet-conjugated perylene diimide with photodynamic/photothermal properties for DNA photocleavage and cancer treatment.
    Colloids and surfaces. B, Biointerfaces, 2020, Volume: 196

    Topics: DNA; Nanoparticles; Neoplasms; Perylene; Phenothiazines; Photochemotherapy; Phototherapy

2020
Preparation and validation of cyclodextrin-based excipients for radioiodinated hypericin applied in a targeted cancer radiotherapy.
    International journal of pharmaceutics, 2021, Apr-15, Volume: 599

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Anthracenes; Cyclodextrins; Excipients; Humans; Neoplasms; Perylene; Solubility; Tissue Distribution

2021
Lysosome-Instructed Self-Assembly of Amino-Acid-Functionalized Perylene Diimide for Multidrug-Resistant Cancer Cells.
    ACS applied materials & interfaces, 2021, Apr-07, Volume: 13, Issue:13

    Topics: Amino Acids; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Imides; Lysosomes; Neoplasms; Perylene

2021
Triphenylamine-perylene diimide conjugate-based organic nanoparticles for photoacoustic imaging and cancer phototherapy.
    Colloids and surfaces. B, Biointerfaces, 2021, Volume: 205

    Topics: HeLa Cells; Humans; Nanoparticles; Neoplasms; Perylene; Photoacoustic Techniques; Phototherapy

2021
Universal colorful staining of cancer tissues and normal tissues for histological diagnosis.
    The Analyst, 2021, Jul-21, Volume: 146, Issue:14

    Topics: Eosine Yellowish-(YS); Humans; Microscopy, Fluorescence; Neoplasms; Perylene; Staining and Labeling

2021
Impact of Semiconducting Perylene Diimide Nanoparticle Size on Lymph Node Mapping and Cancer Imaging.
    ACS nano, 2017, 04-25, Volume: 11, Issue:4

    Topics: 3T3 Cells; Animals; Antineoplastic Agents; Cell Survival; Contrast Media; Copper Radioisotopes; Humans; Imides; Lymph Nodes; Mice; Mice, Nude; Multimodal Imaging; Nanoparticles; Neoplasms; Particle Size; Perylene; Photoacoustic Techniques; Polyethylene Glycols; Positron-Emission Tomography; Semiconductors; Tissue Distribution

2017
Hypericin affects cancer side populations via competitive inhibition of BCRP.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 99

    Topics: Aldehyde Dehydrogenase; Animals; Anthracenes; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Biomarkers, Tumor; Carcinogenesis; Cell Line, Tumor; Clone Cells; Humans; Mice, SCID; Neoplasm Proteins; Neoplasms; Neoplastic Stem Cells; Perylene; Phenotype; Side-Population Cells; Spheroids, Cellular; Substrate Specificity; Survival Analysis

2018
Biodegradable hypocrellin derivative nanovesicle as a near-infrared light-driven theranostic for dually photoactive cancer imaging and therapy.
    Biomaterials, 2018, Volume: 185

    Topics: Animals; Cell Line, Tumor; Female; Mice; Mice, Nude; Nanoshells; Neoplasms; Optical Imaging; Perylene; Photoacoustic Techniques; Photochemotherapy; Photosensitizing Agents; Polyesters; Polyethylene Glycols; Quinones; Theranostic Nanomedicine

2018
Semiconducting Perylene Diimide Nanostructure: Multifunctional Phototheranostic Nanoplatform.
    Accounts of chemical research, 2019, 05-21, Volume: 52, Issue:5

    Topics: Animals; Humans; Hyperthermia, Induced; Imides; Lymph Nodes; Nanoparticles; Neoplasms; Perylene; Photoacoustic Techniques; Phototherapy; Precision Medicine; Rats; Semiconductors; Theranostic Nanomedicine; Thrombosis

2019
ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death.
    Autophagy, 2013, Volume: 9, Issue:9

    Topics: Adenosine Triphosphate; Anthracenes; Autophagy; Autophagy-Related Protein 5; Calreticulin; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cell Proliferation; Dendritic Cells; Gene Knockdown Techniques; Glutathione Peroxidase; Histidine; Humans; Interferon-gamma; Interleukin-6; Microtubule-Associated Proteins; Models, Biological; Neoplasms; Oxidation-Reduction; Perylene; Phenotype; Photochemotherapy; Reactive Oxygen Species

2013
Radioiodinated hypericin: its biodistribution, necrosis avidity and therapeutic efficacy are influenced by formulation.
    Pharmaceutical research, 2014, Volume: 31, Issue:2

    Topics: Animals; Anthracenes; Antineoplastic Agents; Chemistry, Pharmaceutical; Dimethyl Sulfoxide; Iodine Radioisotopes; Liver; Male; Necrosis; Neoplasms; Perylene; Polyethylene Glycols; Radiopharmaceuticals; Rats; Spleen; Tissue Distribution; Water

2014
Internal heavy atom effect of Au(III) and Pt(IV) on hypocrellin A for enhanced in vitro photodynamic therapy of cancer.
    Bioorganic & medicinal chemistry letters, 2013, Oct-01, Volume: 23, Issue:19

    Topics: Cell Survival; Coordination Complexes; Gold; HeLa Cells; Humans; Metals, Heavy; Microscopy, Fluorescence; Models, Biological; Molecular Structure; Neoplasms; Perylene; Phenol; Photosensitizing Agents; Platinum; Quinones; Solubility; Spectroscopy, Fourier Transform Infrared

2013
Hypericin-loaded lipid nanocapsules for photodynamic cancer therapy in vitro.
    Nanoscale, 2013, Nov-07, Volume: 5, Issue:21

    Topics: Anthracenes; Cell Line; Cell Survival; Drug Carriers; HeLa Cells; Humans; Hypericum; Light; Lipids; Microscopy, Video; Nanocapsules; Neoplasms; Particle Size; Perylene; Photochemotherapy; Photosensitizing Agents; Singlet Oxygen; Spectrophotometry, Ultraviolet

2013
A new near infrared photosensitizing nanoplatform containing blue-emitting up-conversion nanoparticles and hypocrellin A for photodynamic therapy of cancer cells.
    Nanoscale, 2013, Dec-07, Volume: 5, Issue:23

    Topics: Cell Line, Tumor; Cell Survival; Contrast Media; Fluorides; Gadolinium; HeLa Cells; Humans; Infrared Rays; Magnetic Resonance Imaging; Metal Nanoparticles; Neoplasms; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Polysorbates; Quinones; Radiography; Singlet Oxygen; Yttrium

2013
Biodistribution and radiation dosimetry of radioiodinated hypericin as a cancer therapeutic.
    International journal of oncology, 2014, Volume: 44, Issue:3

    Topics: Animals; Anthracenes; Female; Humans; Iodine Radioisotopes; Male; Neoplasms; Perylene; Radiation Dosage; Radiometry; Radiopharmaceuticals; Rats; Tissue Distribution

2014
Dual-modal imaging and photodynamic therapy using upconversion nanoparticles for tumor cells.
    The Analyst, 2014, Dec-21, Volume: 139, Issue:24

    Topics: Contrast Media; Fluorides; Gadolinium; HEK293 Cells; HeLa Cells; Humans; Magnetic Resonance Imaging; Microscopy, Confocal; Nanoparticles; Neoplasms; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones; Silicon Dioxide; Yttrium

2014
Multicolor imaging and the anticancer effect of a bifunctional silica nanosystem based on the complex of graphene quantum dots and hypocrellin A.
    Chemical communications (Cambridge, England), 2015, Volume: 51, Issue:2

    Topics: Antineoplastic Agents; Graphite; HeLa Cells; Humans; Nanoparticles; Neoplasms; Optical Imaging; Perylene; Phenol; Photochemotherapy; Quantum Dots; Quinones; Silicon Dioxide

2015
Molecular size, shape, and electric charges: essential for perylene bisimide-based DNA intercalator to localize in cell nuclei and inhibit cancer cell growth.
    ACS applied materials & interfaces, 2015, May-13, Volume: 7, Issue:18

    Topics: Animals; Cattle; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Circular Dichroism; DNA; Drosophila; Electricity; Fluorescence; Humans; Imides; Intercalating Agents; Molecular Weight; Neoplasms; Perylene; Salivary Glands; Spectrometry, Fluorescence; Viscosity

2015
Potentiation of hypericin-mediated photodynamic therapy cytotoxicity by MK-886: focus on ABC transporters, GDF-15 and redox status.
    Photodiagnosis and photodynamic therapy, 2015, Volume: 12, Issue:3

    Topics: Anthracenes; ATP-Binding Cassette Transporters; Caspase 3; Cell Death; Cell Line, Tumor; Drug Synergism; Glutathione; Growth Differentiation Factor 15; Humans; Indoles; Membrane Potential, Mitochondrial; Neoplasms; Oxidation-Reduction; Perylene; Photochemotherapy; Photosensitizing Agents; RNA, Small Interfering

2015
Necrosis targeted radiotherapy with iodine-131-labeled hypericin to improve anticancer efficacy of vascular disrupting treatment in rabbit VX2 tumor models.
    Oncotarget, 2015, Jun-10, Volume: 6, Issue:16

    Topics: Animals; Anthracenes; Autoradiography; Disease Models, Animal; Iodine Radioisotopes; Necrosis; Neoplasms; Neovascularization, Pathologic; Perylene; Rabbits; Radiopharmaceuticals; Random Allocation; Tomography, Emission-Computed, Single-Photon

2015
Resistance to anticancer vaccination effect is controlled by a cancer cell-autonomous phenotype that disrupts immunogenic phagocytic removal.
    Oncotarget, 2015, Sep-29, Volume: 6, Issue:29

    Topics: Animals; Anthracenes; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Calreticulin; Cancer Vaccines; Cell Death; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Humans; Immunotherapy; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mitoxantrone; Neoplasms; Ovarian Neoplasms; Perylene; Phagocytes; Phagocytosis; Phenotype; Photochemotherapy; Prognosis; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

2015
Rational assembly of a biointerfaced core@shell nanocomplex towards selective and highly efficient synergistic photothermal/photodynamic therapy.
    Nanoscale, 2015, Dec-21, Volume: 7, Issue:47

    Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Gold; Humans; Hydrolysis; Liposomes; MCF-7 Cells; Metal Nanoparticles; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Confocal; Nanotechnology; Neoplasms; Perylene; Photochemotherapy; Photons; Quinones; Reactive Oxygen Species; Silicon Dioxide

2015
808 nm Light-triggered and hyaluronic acid-targeted dual-photosensitizers nanoplatform by fully utilizing Nd(3+)-sensitized upconversion emission with enhanced anti-tumor efficacy.
    Biomaterials, 2016, Volume: 101

    Topics: Animals; Apoptosis; Drug Delivery Systems; Female; Fluorides; HeLa Cells; Humans; Hyaluronic Acid; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neodymium; Neoplasms; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones; Reactive Oxygen Species; Titanium; Ultraviolet Rays; Yttrium

2016
Water-soluble and biocompatible sono/photosensitizer nanoparticles for enhanced cancer therapy.
    Nanomedicine (London, England), 2010, Volume: 5, Issue:10

    Topics: Animals; Cell Line, Tumor; Cell Survival; Humans; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Perylene; Photochemotherapy; Photosensitizing Agents; Quinoxalines; Solubility; Water

2010
The possible use of hypericin to overcome drug resistance in cancer treatment.
    Chemico-biological interactions, 2011, Apr-25, Volume: 190, Issue:2-3

    Topics: Anthracenes; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 Enzyme System; Drug Resistance, Neoplasm; Humans; Neoplasms; Perylene

2011
Influence of the vascular damaging agents DMXAA and ZD6126 on hypericin distribution and accumulation in RIF-1 tumors.
    Journal of cancer research and clinical oncology, 2011, Volume: 137, Issue:11

    Topics: Animals; Anthracenes; Antineoplastic Agents; Cell Line, Tumor; Mice; Mice, Inbred C3H; Necrosis; Neoplasms; Neovascularization, Pathologic; Organophosphorus Compounds; Perylene; Telomere-Binding Proteins; Xanthones

2011
Degradation of HIF-1alpha under hypoxia combined with induction of Hsp90 polyubiquitination in cancer cells by hypericin: a unique cancer therapy.
    PloS one, 2011, Volume: 6, Issue:9

    Topics: Anthracenes; Antineoplastic Agents; Blotting, Western; Cathepsin B; Cell Hypoxia; Cell Line; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Humans; Hydrogen-Ion Concentration; Hypoxia-Inducible Factor 1, alpha Subunit; Metabolism; Neoplasms; Perylene; Promoter Regions, Genetic; Protein Binding; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; Ubiquitination; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2011
Pretargeting of necrotic tumors with biotinylated hypericin using 123I-labeled avidin: evaluation of a two-step strategy.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Anthracenes; Antineoplastic Agents; Avidin; Biotin; Biotinylation; Cell Line, Tumor; Contrast Media; Ethanol; Female; Iodine Radioisotopes; Mice; Mice, Inbred C3H; Necrosis; Neoplasms; Perylene; Tissue Distribution

2012
Hypericin-based photodynamic therapy induces surface exposure of damage-associated molecular patterns like HSP70 and calreticulin.
    Cancer immunology, immunotherapy : CII, 2012, Volume: 61, Issue:2

    Topics: Animals; Anthracenes; Anthracyclines; Apoptosis; Cell Line; Dendritic Cells; Hematoporphyrin Photoradiation; Humans; Inflammation; Mice; Neoplasms; Perylene; Protein Disulfide-Isomerases; Reactive Oxygen Species

2012
Perylene-3-ylmethanol: fluorescent organic nanoparticles as a single-component photoresponsive nanocarrier with real-time monitoring of anticancer drug release.
    Journal of the American Chemical Society, 2012, May-09, Volume: 134, Issue:18

    Topics: Antineoplastic Agents; Biocompatible Materials; Chlorambucil; Delayed-Action Preparations; Fluorescent Dyes; HeLa Cells; Humans; Nanoparticles; Neoplasms; Perylene; Photolysis

2012
Development of a new LDL-based transport system for hydrophobic/amphiphilic drug delivery to cancer cells.
    International journal of pharmaceutics, 2012, Oct-15, Volume: 436, Issue:1-2

    Topics: Anthracenes; Cell Line, Tumor; Dextrans; Drug Carriers; Humans; Hydrophobic and Hydrophilic Interactions; Lipoproteins, LDL; Neoplasms; Perylene; Radiation-Sensitizing Agents

2012
Evaluation of perylenediimide derivatives for potential therapeutic benefits on cancer chemotherapy.
    Chemical biology & drug design, 2012, Volume: 80, Issue:5

    Topics: Antineoplastic Agents; Glutathione Transferase; Humans; Imides; Neoplasms; Perylene; Protein Kinase Inhibitors; src-Family Kinases; Structure-Activity Relationship

2012
External heavy-atomic construction of photosensitizer nanoparticles for enhanced in vitro photodynamic therapy of cancer.
    The journal of physical chemistry. B, 2012, Oct-25, Volume: 116, Issue:42

    Topics: Antineoplastic Agents; Cell Death; Cell Survival; Drug Delivery Systems; Gold; HeLa Cells; Humans; Nanoparticles; Neoplasms; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Platinum; Quinones; Silicon Dioxide; Singlet Oxygen; Structure-Activity Relationship; Tumor Cells, Cultured

2012
Aromatic core extension in the series of N-cyclic bay-substituted perylene G-quadruplex ligands: increased telomere damage, antitumor activity, and strong selectivity for neoplastic over healthy cells.
    ChemMedChem, 2012, Volume: 7, Issue:12

    Topics: Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Proliferation; DNA Damage; G-Quadruplexes; Humans; Neoplasms; Perylene; Polycyclic Compounds; Telomere

2012
Alginate-based microcapsules with a molecule recognition linker and photosensitizer for the combined cancer treatment.
    Chemistry, an Asian journal, 2013, Volume: 8, Issue:4

    Topics: Alginates; Capsules; Cell Proliferation; Doxorubicin; Drug Carriers; Glucuronic Acid; HeLa Cells; Hexuronic Acids; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Neoplasms; Perylene; Photosensitizing Agents; Quinones

2013
Bio-distribution and subcellular localization of Hypericin and its role in PDT induced apoptosis in cancer cells.
    International journal of oncology, 2002, Volume: 21, Issue:3

    Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Colonic Neoplasms; Cytochrome c Group; Humans; Intracellular Membranes; Lysosomes; Membrane Potentials; Microscopy, Electron; Mitochondria; Nasopharyngeal Neoplasms; Neoplasms; Perylene; Photochemotherapy; Photosensitizing Agents; Subcellular Fractions; Tissue Distribution; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms

2002
Efficacy of hypocrellin pharmacokinetics in phototherapy.
    International journal of oncology, 2002, Volume: 21, Issue:6

    Topics: Apoptosis; Apoptotic Protease-Activating Factor 1; Bambusa; bcl-2-Associated X Protein; Blotting, Western; Cytochrome c Group; Drugs, Chinese Herbal; Humans; Immunoenzyme Techniques; Lysosomes; Microscopy, Confocal; Mitochondria; Neoplasms; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Quinones; Subcellular Fractions; Tumor Cells, Cultured

2002
Photodynamic-induced vascular damage of the chick chorioallantoic membrane model using perylenequinones.
    International journal of oncology, 2004, Volume: 25, Issue:4

    Topics: Animals; Anthracenes; Blood Vessels; Chickens; Chorioallantoic Membrane; Neoplasms; Perylene; Photochemotherapy; Photosensitizing Agents; Quinones

2004
Induction of heme-oxygenase 1 requires the p38MAPK and PI3K pathways and suppresses apoptotic cell death following hypericin-mediated photodynamic therapy.
    Apoptosis : an international journal on programmed cell death, 2007, Volume: 12, Issue:4

    Topics: Anthracenes; Apoptosis; Cell Line, Tumor; Enzyme Induction; Enzyme Inhibitors; Heme Oxygenase-1; Humans; MAP Kinase Signaling System; Neoplasms; NF-E2-Related Factor 2; p38 Mitogen-Activated Protein Kinases; Perylene; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Photochemotherapy; Radiation-Sensitizing Agents; RNA, Small Interfering

2007
Photosensitizer effects on cancerous cells: a combined study using synchrotron infrared and fluorescence microscopies.
    Biochimica et biophysica acta, 2008, Volume: 1780, Issue:5

    Topics: Cell Nucleus; Cytoplasm; HeLa Cells; Humans; Infrared Rays; Intracellular Space; Light; Microscopy; Microscopy, Fluorescence; Molecular Structure; Neoplasms; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Principal Component Analysis; Quinones; Spectrophotometry, Infrared; Synchrotrons

2008