Page last updated: 2024-11-02

perphenazine and Muscle Contraction

perphenazine has been researched along with Muscle Contraction in 2 studies

Perphenazine: An antipsychotic phenothiazine derivative with actions and uses similar to those of CHLORPROMAZINE.
perphenazine : A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
" The ethers which result from this change have increased lipophilicity compared to their ability to inhibit perphenazine-induced catatonia in rats."3.65Synthesis and preliminary pharmacological activity of aminoalkoxy isosteres of glycolate ester anticholinergics. ( Amdrako, J; Fries, DS, 1977)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fries, DS1
Amdrako, J1
Brown, DM1
Hughes, BO1
Marsden, CD1
Meadows, JC1
Spicer, B1

Trials

1 trial available for perphenazine and Muscle Contraction

ArticleYear
Some initial animal and human pharmacological studies with benapryzine (BRL 1288).
    British journal of pharmacology, 1973, Volume: 47, Issue:3

    Topics: Acetylcholine; Aged; Animals; Antiparkinson Agents; Benzilates; Clinical Trials as Topic; Dose-Respo

1973

Other Studies

1 other study available for perphenazine and Muscle Contraction

ArticleYear
Synthesis and preliminary pharmacological activity of aminoalkoxy isosteres of glycolate ester anticholinergics.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:10

    Topics: Animals; Body Temperature; Catatonia; Chemistry, Pharmaceutical; Glycolates; Humans; In Vitro Techni

1977