perphenazine has been researched along with Muscle Contraction in 2 studies
Perphenazine: An antipsychotic phenothiazine derivative with actions and uses similar to those of CHLORPROMAZINE.
perphenazine : A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
Excerpt | Relevance | Reference |
---|---|---|
" The ethers which result from this change have increased lipophilicity compared to their ability to inhibit perphenazine-induced catatonia in rats." | 3.65 | Synthesis and preliminary pharmacological activity of aminoalkoxy isosteres of glycolate ester anticholinergics. ( Amdrako, J; Fries, DS, 1977) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Fries, DS | 1 |
Amdrako, J | 1 |
Brown, DM | 1 |
Hughes, BO | 1 |
Marsden, CD | 1 |
Meadows, JC | 1 |
Spicer, B | 1 |
1 trial available for perphenazine and Muscle Contraction
Article | Year |
---|---|
Some initial animal and human pharmacological studies with benapryzine (BRL 1288).
Topics: Acetylcholine; Aged; Animals; Antiparkinson Agents; Benzilates; Clinical Trials as Topic; Dose-Respo | 1973 |
1 other study available for perphenazine and Muscle Contraction
Article | Year |
---|---|
Synthesis and preliminary pharmacological activity of aminoalkoxy isosteres of glycolate ester anticholinergics.
Topics: Animals; Body Temperature; Catatonia; Chemistry, Pharmaceutical; Glycolates; Humans; In Vitro Techni | 1977 |