perphenazine has been researched along with Movement Disorders in 35 studies
Perphenazine: An antipsychotic phenothiazine derivative with actions and uses similar to those of CHLORPROMAZINE.
perphenazine : A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10.
Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Improvement was recorded in a double blind study of 18 patients treated with maximum tolerated dosage (mean 18." | 2.64 | Tardive dyskinesia treated with pimozide. ( Calne, DB; Claveria, LE; Haskayne, L; Lodge-Patch, IC; Pallis, CA; Petrie, A; Teychenne, PF, 1975) |
| "Three had primarily choreic movements while five had, in addition, proximal flailing movements of hemiballism." | 1.26 | Treatment of vascular hemiballism and hemichorea. ( Fahn, S; Johnson, WG, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (88.57) | 18.7374 |
| 1990's | 1 (2.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (8.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khouzam, HR | 1 |
| Caroff, SN | 1 |
| Davis, VG | 1 |
| Miller, DD | 1 |
| Davis, SM | 1 |
| Rosenheck, RA | 2 |
| McEvoy, JP | 1 |
| Campbell, EC | 1 |
| Saltz, BL | 1 |
| Riggio, S | 1 |
| Chakos, MH | 1 |
| Swartz, MS | 1 |
| Keefe, RS | 1 |
| Stroup, TS | 1 |
| Lieberman, JA | 1 |
| Chrisphonte, P | 1 |
| Ostroff, RB | 1 |
| EISENBERG, L | 1 |
| GILBERT, A | 1 |
| CYTRYN, L | 1 |
| MOLLING, PA | 1 |
| TROCH, C | 1 |
| WAUMANS, P | 1 |
| CERSTIAENS, F | 1 |
| STRAUBE, W | 1 |
| MELLIWA, H | 1 |
| AYD, FJ | 1 |
| HUNTER, R | 1 |
| EARL, CJ | 1 |
| THRONICROFT, S | 1 |
| Faurbye, A | 1 |
| Clausen, J | 1 |
| Irwin, S | 1 |
| Heath, DA | 1 |
| McGarry, JM | 1 |
| Terry, PM | 1 |
| Connor, DF | 1 |
| Benjamin, S | 1 |
| Ozbayrak, KR | 1 |
| Forrester, RM | 1 |
| Claveria, LE | 1 |
| Teychenne, PF | 1 |
| Calne, DB | 1 |
| Haskayne, L | 1 |
| Petrie, A | 1 |
| Pallis, CA | 1 |
| Lodge-Patch, IC | 1 |
| Johnson, WG | 2 |
| Fahn, S | 2 |
| Kamen, S | 1 |
| Ogita, K | 1 |
| Yagi, G | 1 |
| Itoh, H | 1 |
| Birkmayer, W | 1 |
| Turunen, S | 1 |
| Achté, KA | 1 |
| Bellman, MH | 1 |
| Svestka, J | 2 |
| Náhunek, K | 2 |
| Rodová, A | 2 |
| Cesková, E | 1 |
| Crane, GE | 1 |
| Smeets, RA | 1 |
| Hanlon, TE | 1 |
| Schoenrich, C | 1 |
| Freinek, W | 1 |
| Turek, I | 1 |
| Kurland, AA | 1 |
| Simpson, GM | 1 |
| Krakov, L | 1 |
| Kunz-Bartholini, E | 1 |
| Villeneuve, A | 1 |
| Ramsden, PD | 1 |
| Froggatt, DL | 1 |
| Singer, K | 1 |
| Cheng, MN | 1 |
| Haddenbrock, S | 1 |
| Demars, JP | 1 |
| Radzuweit, H | 1 |
| Knorr, W | 1 |
| Yaryura-Tobias, JA | 1 |
| Wolpert, A | 1 |
| Dana, L | 1 |
| Merlis, S | 1 |
| Fann, WE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparative Effectiveness of Antipsychotic Medications in Patients With Schizophrenia (CATIE Schizophrenia Trial)[NCT00014001] | Phase 4 | 1,600 participants | Interventional | 2000-12-31 | Completed | ||
| Effect of Varenicline on Smoking Cessation in Patients With Schizophrenia: Evaluation of Antipsychotic Drug-Induced Neurological Symptoms as Correlates of Response[NCT03495024] | Phase 4 | 10 participants (Anticipated) | Interventional | 2019-01-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for perphenazine and Movement Disorders
| Article | Year |
|---|---|
Identification and management of tardive dyskinesia: A case series and literature review.
Topics: Adult; Aged; Anti-Dyskinesia Agents; Clonazepam; Diagnosis, Differential; Dopamine Antagonists; Dysk | 2015 |
8 trials available for perphenazine and Movement Disorders
| Article | Year |
|---|---|
Treatment outcomes of patients with tardive dyskinesia and chronic schizophrenia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chi-Square Distribution; Dibenzothiazepines; Female; H | 2011 |
Treatment outcomes of patients with tardive dyskinesia and chronic schizophrenia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chi-Square Distribution; Dibenzothiazepines; Female; H | 2011 |
Treatment outcomes of patients with tardive dyskinesia and chronic schizophrenia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chi-Square Distribution; Dibenzothiazepines; Female; H | 2011 |
Treatment outcomes of patients with tardive dyskinesia and chronic schizophrenia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chi-Square Distribution; Dibenzothiazepines; Female; H | 2011 |
Tardive dyskinesia treated with pimozide.
Topics: Aged; Antipsychotic Agents; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Consciousnes | 1975 |
A controlled comparison of oxypertine and perphenazine in schizophrenic psychoses.
Topics: Adolescent; Adult; Bipolar Disorder; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Indo | 1974 |
Treatment of vascular hemichorea and hemiballismus with perphenazine.
Topics: Chorea; Clinical Trials as Topic; Humans; Hypertension; Hypothalamus; Movement Disorders; Perphenazi | 1974 |
Perphenazine-benztropine mesylate treatment of newly admitted psychiatric patients.
Topics: Adolescent; Adult; Clinical Trials as Topic; Drug Synergism; Extrapyramidal Tracts; Female; Hospital | 1966 |
A controlled trial of combined medications on behavioral and extrapyramidal effects.
Topics: Adult; Aged; Amitriptyline; Analysis of Variance; Clinical Trials as Topic; Extrapyramidal Tracts; H | 1970 |
Neuromuscular effects of long-term phenothiazine medication, electroconvulsive therapy and leucotomy.
Topics: Aged; Chlorpromazine; Clinical Trials as Topic; Electric Stimulation Therapy; Female; Haloperidol; H | 1966 |
Comparison of the therapeutic effect of flupenthixol and perphenazine in schizophrenia.
Topics: Adolescent; Adult; Ethanol; Female; Humans; Male; Middle Aged; Movement Disorders; Perphenazine; Pip | 1970 |
26 other studies available for perphenazine and Movement Disorders
| Article | Year |
|---|---|
Perphenazine suspension: a new, old treatment, side effects and continuous use.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Cholinergic Antagonists; Clinical Trials as Topic; Dru | 2012 |
The effectiveness of psychotherapy alone and in confunction with perphenazine or placebo in the treatment of neurotic and hyperkinetic children.
Topics: Child; Humans; Infant; Movement Disorders; Neurotic Disorders; Perphenazine; Placebos; Psychotherapy | 1961 |
[7 Cases of intolerance to perphenazine].
Topics: Humans; Movement; Movement Disorders; Perphenazine | 1960 |
[On the continuous treatment of extrapyramidal hyperkinesia with perphenazine].
Topics: Extrapyramidal Tracts; Humans; Hyperkinesis; Movement Disorders; Perphenazine | 1962 |
PERPHENAZINE: A REAPPRAISAL AFTER EIGHT YEARS.
Topics: Central Nervous System Diseases; Extrapyramidal Tracts; Movement Disorders; Perphenazine; Pharmacolo | 1964 |
AN APPARENTLY IRREVERSIBLE SYNDROME OF ABNORMAL MOVEMENTS FOLLOWING PHENOTHIAZINE MEDICATION.
Topics: Brain; Brain Damage, Chronic; Brain Diseases; Chlorpromazine; Chorea; Diagnosis, Differential; Elect | 1964 |
CHANGES IN SERUM PROTEINS AND CEREBROSPINAL FLUID PROTEINS DURING PHARMACOTHERAPY OF PSYCHOSES.
Topics: Alcoholism; Bipolar Disorder; Blood Proteins; Cerebrospinal Fluid Proteins; Chlorpromazine; Drug The | 1964 |
Considerations for the pre-clinical evaluation of new psychiatric drugs: a case study with phenothiazine-like tranquilizers.
Topics: Aggression; Animals; Ataxia; Behavior, Animal; Catalepsy; Emotions; Extrapyramidal Tracts; Fear; Flu | 1966 |
Phenothiazines in early labour.
Topics: Adult; Diagnosis, Differential; Female; Humans; Hyperemesis Gravidarum; Movement Disorders; Perphena | 1967 |
Side-effects of phenothiazines.
Topics: Adult; Female; Fluphenazine; Humans; Male; Movement Disorders; Perphenazine; Pregnancy; Trifluoperaz | 1967 |
Case study: neuroleptic withdrawal dyskinesia exacerbated by ongoing stimulant treatment.
Topics: Antipsychotic Agents; Dextroamphetamine; Diphenhydramine; Fluoxetine; Humans; Male; Mental Disorders | 1995 |
Letter: Side-effects of perphenazine.
Topics: Adolescent; Erythema; Female; Humans; Movement Disorders; Muscle Rigidity; Oculomotor Muscles; Paral | 1975 |
Treatment of vascular hemiballism and hemichorea.
Topics: Cerebrovascular Disorders; Chorea; Dose-Response Relationship, Drug; Humans; Movement Disorders; Per | 1977 |
Tardive dyskinesia. A significant syndrome for geriatric dentistry.
Topics: Aged; Arteriosclerosis; Bruxism; Chlorpromazine; Dementia; Denture, Complete; Depression; Depressive | 1975 |
Comparative analysis of persistent dyskinesias of long-term usage with neuroleptics in France and in Japan.
Topics: Adult; Chlorpromazine; Female; Fluphenazine; France; Humans; Japan; Male; Middle Aged; Movement Diso | 1975 |
[Experimental findings and new aspects in extrapyramidal diseases].
Topics: 5-Hydroxytryptophan; Blood Pressure; Body Temperature Regulation; Chorea; Dihydroxyphenylalanine; Do | 1966 |
The bucco-linguo-masticatory syndrome as a side-effect of neuroleptics therapy.
Topics: Adult; Aged; Brain Damage, Chronic; Cheek; Chlorpromazine; Chlorprothixene; Clopenthixol; Female; Ha | 1967 |
Treatment of phenothiazine drug intoxication with benztropine.
Topics: Antiparkinson Agents; Benztropine; Child; Female; Humans; Infant; Injections, Intravenous; Male; Mov | 1974 |
Tardive dyskinesia and drug therapy in geriatric patients.
Topics: Aged; Chlorpromazine; Diagnosis, Differential; Female; Hospitalization; Hospitals, Psychiatric; Huma | 1974 |
The rabbit syndrome. A peculiar extrapyramidal reaction.
Topics: Aged; Anxiety; Basal Ganglia Diseases; Benztropine; Chlorpromazine; Fatigue; Female; Humans; Male; M | 1972 |
Idiosyncratic responses to phenothiazines.
Topics: Basal Ganglia Diseases; Diazepam; Humans; Movement Disorders; Parasympatholytics; Perphenazine; Trop | 1972 |
Thiopropazate hydrochloride in persistent dyskinesia.
Topics: Humans; Movement Disorders; Perphenazine; Phenothiazines; Piperazines; Placebos; Tranquilizing Agent | 1971 |
[On the mode of action and the question of central organic late damages of continuous neuroleptic treatment].
Topics: Aged; Brain Stem; Butyrophenones; Central Nervous System; Cerebral Ventriculography; Extrapyramidal | 1966 |
[Influencing of biological and immunologic pregnancy reactions by psychotropic drugs].
Topics: Adolescent; Adult; Aged; Butyrophenones; Chlorpromazine; Dementia; Depressive Disorder, Major; Dysau | 1969 |
Action of L-Dopa in drug induced extrapyramidalism.
Topics: Adult; Chlorpromazine; Chronic Disease; Dihydroxyphenylalanine; Extrapyramidal Tracts; Female; Human | 1970 |
Use of methylphenidate to counteract acute dystonic effects of phenothiazines.
Topics: Adult; Humans; Male; Methylphenidate; Movement Disorders; Perphenazine; Schizophrenia; Torticollis; | 1966 |