Page last updated: 2024-11-02

perphenazine and Movement Disorders

perphenazine has been researched along with Movement Disorders in 35 studies

Perphenazine: An antipsychotic phenothiazine derivative with actions and uses similar to those of CHLORPROMAZINE.
perphenazine : A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10.

Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.

Research Excerpts

ExcerptRelevanceReference
" Improvement was recorded in a double blind study of 18 patients treated with maximum tolerated dosage (mean 18."2.64Tardive dyskinesia treated with pimozide. ( Calne, DB; Claveria, LE; Haskayne, L; Lodge-Patch, IC; Pallis, CA; Petrie, A; Teychenne, PF, 1975)
"Three had primarily choreic movements while five had, in addition, proximal flailing movements of hemiballism."1.26Treatment of vascular hemiballism and hemichorea. ( Fahn, S; Johnson, WG, 1977)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199031 (88.57)18.7374
1990's1 (2.86)18.2507
2000's0 (0.00)29.6817
2010's3 (8.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khouzam, HR1
Caroff, SN1
Davis, VG1
Miller, DD1
Davis, SM1
Rosenheck, RA2
McEvoy, JP1
Campbell, EC1
Saltz, BL1
Riggio, S1
Chakos, MH1
Swartz, MS1
Keefe, RS1
Stroup, TS1
Lieberman, JA1
Chrisphonte, P1
Ostroff, RB1
EISENBERG, L1
GILBERT, A1
CYTRYN, L1
MOLLING, PA1
TROCH, C1
WAUMANS, P1
CERSTIAENS, F1
STRAUBE, W1
MELLIWA, H1
AYD, FJ1
HUNTER, R1
EARL, CJ1
THRONICROFT, S1
Faurbye, A1
Clausen, J1
Irwin, S1
Heath, DA1
McGarry, JM1
Terry, PM1
Connor, DF1
Benjamin, S1
Ozbayrak, KR1
Forrester, RM1
Claveria, LE1
Teychenne, PF1
Calne, DB1
Haskayne, L1
Petrie, A1
Pallis, CA1
Lodge-Patch, IC1
Johnson, WG2
Fahn, S2
Kamen, S1
Ogita, K1
Yagi, G1
Itoh, H1
Birkmayer, W1
Turunen, S1
Achté, KA1
Bellman, MH1
Svestka, J2
Náhunek, K2
Rodová, A2
Cesková, E1
Crane, GE1
Smeets, RA1
Hanlon, TE1
Schoenrich, C1
Freinek, W1
Turek, I1
Kurland, AA1
Simpson, GM1
Krakov, L1
Kunz-Bartholini, E1
Villeneuve, A1
Ramsden, PD1
Froggatt, DL1
Singer, K1
Cheng, MN1
Haddenbrock, S1
Demars, JP1
Radzuweit, H1
Knorr, W1
Yaryura-Tobias, JA1
Wolpert, A1
Dana, L1
Merlis, S1
Fann, WE1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparative Effectiveness of Antipsychotic Medications in Patients With Schizophrenia (CATIE Schizophrenia Trial)[NCT00014001]Phase 41,600 participants Interventional2000-12-31Completed
Effect of Varenicline on Smoking Cessation in Patients With Schizophrenia: Evaluation of Antipsychotic Drug-Induced Neurological Symptoms as Correlates of Response[NCT03495024]Phase 410 participants (Anticipated)Interventional2019-01-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for perphenazine and Movement Disorders

ArticleYear
Identification and management of tardive dyskinesia: A case series and literature review.
    Postgraduate medicine, 2015, Volume: 127, Issue:7

    Topics: Adult; Aged; Anti-Dyskinesia Agents; Clonazepam; Diagnosis, Differential; Dopamine Antagonists; Dysk

2015

Trials

8 trials available for perphenazine and Movement Disorders

ArticleYear
Treatment outcomes of patients with tardive dyskinesia and chronic schizophrenia.
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chi-Square Distribution; Dibenzothiazepines; Female; H

2011
Treatment outcomes of patients with tardive dyskinesia and chronic schizophrenia.
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chi-Square Distribution; Dibenzothiazepines; Female; H

2011
Treatment outcomes of patients with tardive dyskinesia and chronic schizophrenia.
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chi-Square Distribution; Dibenzothiazepines; Female; H

2011
Treatment outcomes of patients with tardive dyskinesia and chronic schizophrenia.
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chi-Square Distribution; Dibenzothiazepines; Female; H

2011
Tardive dyskinesia treated with pimozide.
    Journal of the neurological sciences, 1975, Volume: 24, Issue:4

    Topics: Aged; Antipsychotic Agents; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Consciousnes

1975
A controlled comparison of oxypertine and perphenazine in schizophrenic psychoses.
    Activitas nervosa superior, 1974, Volume: 16, Issue:3

    Topics: Adolescent; Adult; Bipolar Disorder; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Indo

1974
Treatment of vascular hemichorea and hemiballismus with perphenazine.
    Transactions of the American Neurological Association, 1974, Volume: 99

    Topics: Chorea; Clinical Trials as Topic; Humans; Hypertension; Hypothalamus; Movement Disorders; Perphenazi

1974
Perphenazine-benztropine mesylate treatment of newly admitted psychiatric patients.
    Psychopharmacologia, 1966, Volume: 9, Issue:4

    Topics: Adolescent; Adult; Clinical Trials as Topic; Drug Synergism; Extrapyramidal Tracts; Female; Hospital

1966
A controlled trial of combined medications on behavioral and extrapyramidal effects.
    Acta psychiatrica Scandinavica. Supplementum, 1970, Volume: 212

    Topics: Adult; Aged; Amitriptyline; Analysis of Variance; Clinical Trials as Topic; Extrapyramidal Tracts; H

1970
Neuromuscular effects of long-term phenothiazine medication, electroconvulsive therapy and leucotomy.
    The Journal of nervous and mental disease, 1966, Volume: 143, Issue:1

    Topics: Aged; Chlorpromazine; Clinical Trials as Topic; Electric Stimulation Therapy; Female; Haloperidol; H

1966
Comparison of the therapeutic effect of flupenthixol and perphenazine in schizophrenia.
    Activitas nervosa superior, 1970, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Ethanol; Female; Humans; Male; Middle Aged; Movement Disorders; Perphenazine; Pip

1970

Other Studies

26 other studies available for perphenazine and Movement Disorders

ArticleYear
Perphenazine suspension: a new, old treatment, side effects and continuous use.
    The Psychiatric quarterly, 2012, Volume: 83, Issue:3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Cholinergic Antagonists; Clinical Trials as Topic; Dru

2012
The effectiveness of psychotherapy alone and in confunction with perphenazine or placebo in the treatment of neurotic and hyperkinetic children.
    The American journal of psychiatry, 1961, Volume: 117

    Topics: Child; Humans; Infant; Movement Disorders; Neurotic Disorders; Perphenazine; Placebos; Psychotherapy

1961
[7 Cases of intolerance to perphenazine].
    Belgisch tijdschrift voor geneeskunde, 1960, May-01, Volume: 16

    Topics: Humans; Movement; Movement Disorders; Perphenazine

1960
[On the continuous treatment of extrapyramidal hyperkinesia with perphenazine].
    Der Nervenarzt, 1962, Volume: 33

    Topics: Extrapyramidal Tracts; Humans; Hyperkinesis; Movement Disorders; Perphenazine

1962
PERPHENAZINE: A REAPPRAISAL AFTER EIGHT YEARS.
    Diseases of the nervous system, 1964, Volume: 25

    Topics: Central Nervous System Diseases; Extrapyramidal Tracts; Movement Disorders; Perphenazine; Pharmacolo

1964
AN APPARENTLY IRREVERSIBLE SYNDROME OF ABNORMAL MOVEMENTS FOLLOWING PHENOTHIAZINE MEDICATION.
    Proceedings of the Royal Society of Medicine, 1964, Volume: 57

    Topics: Brain; Brain Damage, Chronic; Brain Diseases; Chlorpromazine; Chorea; Diagnosis, Differential; Elect

1964
CHANGES IN SERUM PROTEINS AND CEREBROSPINAL FLUID PROTEINS DURING PHARMACOTHERAPY OF PSYCHOSES.
    Acta psychiatrica Scandinavica, 1964, Volume: 40, Issue:1

    Topics: Alcoholism; Bipolar Disorder; Blood Proteins; Cerebrospinal Fluid Proteins; Chlorpromazine; Drug The

1964
Considerations for the pre-clinical evaluation of new psychiatric drugs: a case study with phenothiazine-like tranquilizers.
    Psychopharmacologia, 1966, Volume: 9, Issue:4

    Topics: Aggression; Animals; Ataxia; Behavior, Animal; Catalepsy; Emotions; Extrapyramidal Tracts; Fear; Flu

1966
Phenothiazines in early labour.
    British medical journal, 1967, Feb-11, Volume: 1, Issue:5536

    Topics: Adult; Diagnosis, Differential; Female; Humans; Hyperemesis Gravidarum; Movement Disorders; Perphena

1967
Side-effects of phenothiazines.
    British medical journal, 1967, Apr-01, Volume: 2, Issue:5543

    Topics: Adult; Female; Fluphenazine; Humans; Male; Movement Disorders; Perphenazine; Pregnancy; Trifluoperaz

1967
Case study: neuroleptic withdrawal dyskinesia exacerbated by ongoing stimulant treatment.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1995, Volume: 34, Issue:11

    Topics: Antipsychotic Agents; Dextroamphetamine; Diphenhydramine; Fluoxetine; Humans; Male; Mental Disorders

1995
Letter: Side-effects of perphenazine.
    Lancet (London, England), 1975, Jun-21, Volume: 1, Issue:7921

    Topics: Adolescent; Erythema; Female; Humans; Movement Disorders; Muscle Rigidity; Oculomotor Muscles; Paral

1975
Treatment of vascular hemiballism and hemichorea.
    Neurology, 1977, Volume: 27, Issue:7

    Topics: Cerebrovascular Disorders; Chorea; Dose-Response Relationship, Drug; Humans; Movement Disorders; Per

1977
Tardive dyskinesia. A significant syndrome for geriatric dentistry.
    Oral surgery, oral medicine, and oral pathology, 1975, Volume: 39, Issue:1

    Topics: Aged; Arteriosclerosis; Bruxism; Chlorpromazine; Dementia; Denture, Complete; Depression; Depressive

1975
Comparative analysis of persistent dyskinesias of long-term usage with neuroleptics in France and in Japan.
    Folia psychiatrica et neurologica japonica, 1975, Volume: 29, Issue:4

    Topics: Adult; Chlorpromazine; Female; Fluphenazine; France; Humans; Japan; Male; Middle Aged; Movement Diso

1975
[Experimental findings and new aspects in extrapyramidal diseases].
    Wiener Zeitschrift fur Nervenheilkunde und deren Grenzgebiete, 1966, Volume: 23, Issue:1

    Topics: 5-Hydroxytryptophan; Blood Pressure; Body Temperature Regulation; Chorea; Dihydroxyphenylalanine; Do

1966
The bucco-linguo-masticatory syndrome as a side-effect of neuroleptics therapy.
    The Psychiatric quarterly, 1967, Volume: 41, Issue:2

    Topics: Adult; Aged; Brain Damage, Chronic; Cheek; Chlorpromazine; Chlorprothixene; Clopenthixol; Female; Ha

1967
Treatment of phenothiazine drug intoxication with benztropine.
    Archives of disease in childhood, 1974, Volume: 49, Issue:8

    Topics: Antiparkinson Agents; Benztropine; Child; Female; Humans; Infant; Injections, Intravenous; Male; Mov

1974
Tardive dyskinesia and drug therapy in geriatric patients.
    Archives of general psychiatry, 1974, Volume: 30, Issue:3

    Topics: Aged; Chlorpromazine; Diagnosis, Differential; Female; Hospitalization; Hospitals, Psychiatric; Huma

1974
The rabbit syndrome. A peculiar extrapyramidal reaction.
    Canadian Psychiatric Association journal, 1972, Volume: 17, Issue:2

    Topics: Aged; Anxiety; Basal Ganglia Diseases; Benztropine; Chlorpromazine; Fatigue; Female; Humans; Male; M

1972
Idiosyncratic responses to phenothiazines.
    British medical journal, 1972, Jan-22, Volume: 1, Issue:5794

    Topics: Basal Ganglia Diseases; Diazepam; Humans; Movement Disorders; Parasympatholytics; Perphenazine; Trop

1972
Thiopropazate hydrochloride in persistent dyskinesia.
    British medical journal, 1971, Dec-04, Volume: 4, Issue:5787

    Topics: Humans; Movement Disorders; Perphenazine; Phenothiazines; Piperazines; Placebos; Tranquilizing Agent

1971
[On the mode of action and the question of central organic late damages of continuous neuroleptic treatment].
    Der Nervenarzt, 1966, Volume: 37, Issue:5

    Topics: Aged; Brain Stem; Butyrophenones; Central Nervous System; Cerebral Ventriculography; Extrapyramidal

1966
[Influencing of biological and immunologic pregnancy reactions by psychotropic drugs].
    Endokrinologie, 1969, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Aged; Butyrophenones; Chlorpromazine; Dementia; Depressive Disorder, Major; Dysau

1969
Action of L-Dopa in drug induced extrapyramidalism.
    Diseases of the nervous system, 1970, Volume: 31, Issue:1

    Topics: Adult; Chlorpromazine; Chronic Disease; Dihydroxyphenylalanine; Extrapyramidal Tracts; Female; Human

1970
Use of methylphenidate to counteract acute dystonic effects of phenothiazines.
    The American journal of psychiatry, 1966, Volume: 122, Issue:11

    Topics: Adult; Humans; Male; Methylphenidate; Movement Disorders; Perphenazine; Schizophrenia; Torticollis;

1966