perphenazine has been researched along with Melanoma in 2 studies
Perphenazine: An antipsychotic phenothiazine derivative with actions and uses similar to those of CHLORPROMAZINE.
perphenazine : A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cutaneous melanoma is least common (only about 1% of skin cancers) but is the deadliest malignant tumor." | 5.51 | Antimelanoma activity of perphenazine and prochlorperazine in human COLO829 and C32 cell lines. ( Otręba, M; Pajor, M; Warncke, JD, 2019) |
| "Cutaneous melanoma is least common (only about 1% of skin cancers) but is the deadliest malignant tumor." | 1.51 | Antimelanoma activity of perphenazine and prochlorperazine in human COLO829 and C32 cell lines. ( Otręba, M; Pajor, M; Warncke, JD, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kuzu, OF | 1 |
| Gowda, R | 1 |
| Noory, MA | 1 |
| Robertson, GP | 1 |
| Otręba, M | 1 |
| Pajor, M | 1 |
| Warncke, JD | 1 |
2 other studies available for perphenazine and Melanoma
| Article | Year |
|---|---|
Modulating cancer cell survival by targeting intracellular cholesterol transport.
Topics: Administration, Intravenous; Administration, Oral; Animals; Antidepressive Agents, Tricyclic; Antips | 2017 |
Antimelanoma activity of perphenazine and prochlorperazine in human COLO829 and C32 cell lines.
Topics: Antineoplastic Agents; Antipsychotic Agents; Cell Line, Tumor; Cell Movement; Cell Survival; Dose-Re | 2019 |