Page last updated: 2024-11-02

perphenazine and Hyperprolactinemia

perphenazine has been researched along with Hyperprolactinemia in 4 studies

Perphenazine: An antipsychotic phenothiazine derivative with actions and uses similar to those of CHLORPROMAZINE.
perphenazine : A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10.

Hyperprolactinemia: Increased levels of PROLACTIN in the BLOOD, which may be associated with AMENORRHEA and GALACTORRHEA. Relatively common etiologies include PROLACTINOMA, medication effect, KIDNEY FAILURE, granulomatous diseases of the PITUITARY GLAND, and disorders which interfere with the hypothalamic inhibition of prolactin release. Ectopic (non-pituitary) production of prolactin may also occur. (From Joynt, Clinical Neurology, 1992, Ch36, pp77-8)

Research Excerpts

ExcerptRelevanceReference
"Prolactin-secreting pituitary adenomas were selectively removed through a transsphenoidal approach from 120 women."1.27Gradual recovery of lactotroph responsiveness to dynamic stimulation following surgical removal of prolactinomas: long-term follow-up studies. ( Arafah, BM; Brodkey, JS; Pearson, OH, 1986)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, E1
Correll, CU1
Mao, L1
Starr, HL1
Alphs, L1
Canuso, CM1
Hanau, M1
Jhamb, KK1
Green, AI1
Arafah, BM1
Brodkey, JS1
Pearson, OH1
Mattox, JH1
Fortunato, SJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Trial to Compare the Efficiency and Side Effect Between Olanzapine and Long-acting Paliperidone Palmitate Injection in Schizophrenia[NCT02918825]100 participants (Actual)Interventional2016-09-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for perphenazine and Hyperprolactinemia

ArticleYear
Once-monthly paliperidone palmitate compared with conventional and atypical daily oral antipsychotic treatment in patients with schizophrenia.
    CNS spectrums, 2016, Volume: 21, Issue:6

    Topics: Administration, Oral; Adult; Antipsychotic Agents; Aripiprazole; Basal Ganglia Diseases; Benzodiazep

2016

Other Studies

3 other studies available for perphenazine and Hyperprolactinemia

ArticleYear
Olanzapine use in women with antipsychotic-induced hyperprolactinemia.
    The American journal of psychiatry, 1998, Volume: 155, Issue:10

    Topics: Adult; Amenorrhea; Antipsychotic Agents; Benzodiazepines; Female; Galactorrhea; Humans; Hyperprolact

1998
Gradual recovery of lactotroph responsiveness to dynamic stimulation following surgical removal of prolactinomas: long-term follow-up studies.
    Metabolism: clinical and experimental, 1986, Volume: 35, Issue:10

    Topics: Adenoma; Female; Follow-Up Studies; Humans; Hyperprolactinemia; Perphenazine; Pituitary Gland; Pitui

1986
Prolactin response to perphenazine. A sensitive and specific test for pituitary tumor in hyperprolactinemic women.
    The Journal of reproductive medicine, 1986, Volume: 31, Issue:12

    Topics: Adenoma; Adult; Female; Humans; Hyperprolactinemia; Kinetics; Middle Aged; Perphenazine; Pituitary N

1986