perphenazine has been researched along with Genetic Predisposition in 2 studies
Perphenazine: An antipsychotic phenothiazine derivative with actions and uses similar to those of CHLORPROMAZINE.
perphenazine : A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dopaminergic and serotonergic pathways are involved in the therapeutic and adverse effects of the drug." | 2.73 | Serotonin and dopamine receptor gene polymorphisms and the risk of extrapyramidal side effects in perphenazine-treated schizophrenic patients. ( Dahl, ML; Gunes, A; Jaanson, P; Scordo, MG, 2007) |
| "Treatment with perphenazine was more effective than treatment with quetiapine (p = ." | 2.73 | Ethnic stratification of the association of RGS4 variants with antipsychotic treatment response in schizophrenia. ( Campbell, DB; Ebert, PJ; Levitt, P; Lieberman, J; Skelly, T; Stroup, TS; Sullivan, PF, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gunes, A | 1 |
| Scordo, MG | 1 |
| Jaanson, P | 1 |
| Dahl, ML | 1 |
| Campbell, DB | 1 |
| Ebert, PJ | 1 |
| Skelly, T | 1 |
| Stroup, TS | 1 |
| Lieberman, J | 1 |
| Levitt, P | 1 |
| Sullivan, PF | 1 |
2 trials available for perphenazine and Genetic Predisposition
| Article | Year |
|---|---|
Serotonin and dopamine receptor gene polymorphisms and the risk of extrapyramidal side effects in perphenazine-treated schizophrenic patients.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Dopamine Antagonists; Dyskinesia, Drug-Induced; Femal | 2007 |
Ethnic stratification of the association of RGS4 variants with antipsychotic treatment response in schizophrenia.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Antipsychotic Agents; Dibenzothiazepines; Ethnicity; | 2008 |