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perphenazine and Experimental Mammary Neoplasms

perphenazine has been researched along with Experimental Mammary Neoplasms in 34 studies

Perphenazine: An antipsychotic phenothiazine derivative with actions and uses similar to those of CHLORPROMAZINE.
perphenazine : A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10.

Research Excerpts

ExcerptRelevanceReference
"The effect of chronic administration of a high dose of oestradiol benzoate (OB) on growth and prolactin receptor content of the N-nitrosomethylurea (NMU)-induced rat mammary tumour was investigated."1.26Effect of high-dose oestrogen administration on the growth and prolactin receptor content of N-nitrosomethylurea-induced mammary tumours in the rat. ( Arafah, BM; Manni, A; Pearson, OH; Rainieri, J, 1982)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199029 (85.29)18.7374
1990's4 (11.76)18.2507
2000's1 (2.94)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hollander, VP4
Khan, S2
Manni, A6
Rainieri, J2
Arafah, BM2
Pearson, OH4
Finegan, HM1
Sakamoto, S1
Kawasaki, T1
Yoshino, H1
Kudo, H1
Okamoto, R1
Clinton, SK1
Mulloy, AL1
Visek, WJ1
Sinha, YN3
Gilligan, TA1
Minasian-Batmanian, LC1
Jabara, AG1
Guzman, RC1
Yang, J1
Rajkumar, L1
Thordarson, G1
Chen, X1
Nandi, S1
Sivaraman, L1
Conneely, OM1
Medina, D1
O'Malley, BW1
Powell, BL1
Diamond, EJ3
Koprak, S2
Rose, DP1
Pruitt, B1
Nardacci, NJ1
McGuire, WL2
Trujillo, JE1
Hawkins, RA2
Hill, A1
Freedman, B1
Killen, E1
Buchan, P3
Miller, WR3
Forrest, AP1
Vlahakis, G1
Vanderlaan, WP2
Duncan, KL1
Don, BR1
Schaeffer, LD1
Puffer, HW1
Lee, YT1
Warner, NE1
Wicha, MS1
Liotta, LA1
Kidwell, WR1
Nasr, H1
Giladi, M1
Hallowes, RC1
Rudland, PS1
Lewis, DJ1
Bennet, D1
Durbin, H1
Salocks, CB1
Fraser, AT1
Shen, SK1
Khin, S1
Biser, N1
English, H1
Badger, B2
Martel, J1
Demers, L2
Wijsman, JH1
Cornelisse, CJ1
Keijzer, R1
van de Velde, CJ1
van Dierendonck, JH1
Wang, BC1
Kennan, WS1
Yasukawa-Barnes, J1
Lindstrom, MJ1
Gould, MN1
Lynch, J1
Glikman, P1
Sharoni, Y1
Radian, S1
Levy, J1
Welsch, CW1
O'Connor, DH1
Aylsworth, CF1
Sheffield, LG1
Lancaster, S1
English, HF1
Demers, LM1
Ben-David, M1
Heston, WE1
Rodbard, D1
Bogden, AE1
Taylor, DJ1
Kuo, EY1
Mason, MM1
Speropoulos, A1

Other Studies

34 other studies available for perphenazine and Experimental Mammary Neoplasms

ArticleYear
The ether-catalyzed dissociation rate of estradiol-receptor complex distinguishes between hormone-sensitive and resistant rat mammary tumors.
    Journal of steroid biochemistry, 1980, Volume: 12

    Topics: Animals; Castration; Cytosol; Estradiol; Female; Mammary Neoplasms, Experimental; Perphenazine; Prol

1980
Effect of high-dose oestrogen administration on the growth and prolactin receptor content of N-nitrosomethylurea-induced mammary tumours in the rat.
    The Journal of endocrinology, 1982, Volume: 93, Issue:1

    Topics: Animals; Cell Division; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Perph

1982
Role of estrogen and prolactin in the growth and receptor levels of N-nitrosomethylurea-induced rat mammary tumors.
    Cancer research, 1982, Volume: 42, Issue:9

    Topics: Animals; Bromocriptine; Castration; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitros

1982
Effects of estrogen and prolactin on thymidine kinase isozyme activities in DMBA-induced rat mammary tumor.
    Toxicology letters, 1984, Volume: 21, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromatography, DEAE-Cellulose; Chromatography, High Pres

1984
Effects of dietary lipid saturation on prolactin secretion, carcinogen metabolism and mammary carcinogenesis in rats.
    The Journal of nutrition, 1984, Volume: 114, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Dietary Fats; Female; Mammary N

1984
A cleaved form of prolactin in the mouse pituitary gland: identification and comparison of in vitro synthesis and release in strains with high and low incidences of mammary tumors.
    Endocrinology, 1984, Volume: 114, Issue:6

    Topics: Animals; Castration; Estradiol; Female; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3

1984
Hormone and drug effects on growth of DMBA mammary tumours and plasma prolactin levels in adreno-ovariectomized rats.
    British journal of cancer, 1981, Volume: 43, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenalectomy; Animals; Castration; Dose-Response Relationship, Dr

1981
Hormonal prevention of breast cancer: mimicking the protective effect of pregnancy.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Mar-02, Volume: 96, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Cell Differentiation; Cell Division; Estradiol;

1999
p53 is a potential mediator of pregnancy and hormone-induced resistance to mammary carcinogenesis.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Oct-23, Volume: 98, Issue:22

    Topics: Animals; Cell Differentiation; Cell Division; Estrogens; Female; Male; Mammary Neoplasms, Experiment

2001
Prolactin binding in ovariectomy-responsive and ovariectomy-nonresponsive rat mammary carcinoma.
    Cancer research, 1977, Volume: 37, Issue:5

    Topics: Animals; Binding, Competitive; Castration; Cell Membrane; Female; Hydrogen-Ion Concentration; Mammar

1977
Modification of the effect of a gonadoliberin analog on 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors by hormone replacement.
    Cancer research, 1979, Volume: 39, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Gonadotropin-Releasing Hormone; Hormon

1979
Casein and alpha-lactalbumin messenger RNA in experimental breast cancer.
    Cancer research, 1977, Volume: 37, Issue:4

    Topics: Animals; Antibodies; Caseins; Female; Lactalbumin; Lactation; Mammary Neoplasms, Experimental; Perph

1977
Predominant role of prolactin in stimulating the growth of 7, 12-dimethylbenz(a)anthracene-induced rat mammary tumor.
    Cancer research, 1977, Volume: 37, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetonitriles; Animals; Benz(a)Anthracenes; Drug Administration Sc

1977
Oestrogen receptor activity and endocrine status in DMBA-induced rat mammary tumours.
    European journal of cancer, 1977, Mar-29, Volume: 13, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Estradiol; Estrogens; Estrus; Female; Mammary

1977
Perphenazine and testosterone metabolism by mammary tumours in oophorectomized rats [proceedings].
    Biochemical Society transactions, 1978, Volume: 6, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Female; Mammary Neoplasms, Experimental; Perp

1978
Serum, pituitary and urine concentrations of prolactin and growth hormone in eight strains of mice with varying incidence of mammary tumors.
    International journal of cancer, 1979, Oct-15, Volume: 24, Issue:4

    Topics: Animals; Female; Growth Hormone; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, I

1979
An introductory study of the influence and role of prolactin in mammary tumor growth.
    Proceedings of the Western Pharmacology Society, 1977, Volume: 20

    Topics: Animals; Ergolines; Female; In Vitro Techniques; Mammary Neoplasms, Experimental; Perphenazine; Prol

1977
Effects of free fatty acids on the growth of normal and neoplastic rat mammary epithelial cells.
    Cancer research, 1979, Volume: 39, Issue:2 Pt 1

    Topics: Animals; Cell Division; Epithelium; Fatty Acids, Nonesterified; Female; Hormones; In Vitro Technique

1979
Inhibition of prolactin secretion by ergot alkaloids.
    Acta endocrinologica, 1975, Volume: 80, Issue:3

    Topics: Animals; Depression, Chemical; Dihydroergotamine; Dihydroergotoxine; Ergolines; Ergot Alkaloids; Erg

1975
Estradiol binding in ovariectomy-responsive and -nonresponsive rat mammary carcinoma.
    Cancer research, 1977, Volume: 37, Issue:6

    Topics: Animals; Castration; Cytosol; Estradiol; Female; Mammary Neoplasms, Experimental; Ovary; Perphenazin

1977
Comparison of the effects of hormones on DNA synthesis in cell cultures of nonneoplastic and neoplastic mammary epithelium from rats.
    Cancer research, 1977, Volume: 37, Issue:8 Pt 1

    Topics: Animals; Cells, Cultured; Corticosterone; DNA; DNA, Neoplasm; Epithelial Cells; Epithelium; Estradio

1977
Circulating levels of prolactin and growth hormone and natural incidence of mammary tumors in mice.
    Journal of toxicology and environmental health. Supplement, 1976, Volume: 1

    Topics: Age Factors; Animals; Biological Assay; Cattle; Female; Growth Hormone; Humans; Lactation; Male; Mam

1976
The effect of perphenazine treatment on testosterone metabolism by established rat mammary carcinomas.
    Biochemical Society transactions, 1976, Volume: 4, Issue:6

    Topics: Androstane-3,17-diol; Animals; Dihydrotestosterone; DNA, Neoplasm; Female; Mammary Neoplasms, Experi

1976
The conversion of an ovariectomy-nonresponsive to an ovariectomy-responsive mammary tumor strain.
    Cancer research, 1976, Volume: 36, Issue:1

    Topics: Animals; Castration; Estradiol; Female; Growth Hormone; Hormones, Ectopic; Mammary Neoplasms, Experi

1976
Synchronization of breast cancer cell proliferation in vivo by combined hormonal and polyamine manipulation.
    Cancer research, 1992, Oct-15, Volume: 52, Issue:20

    Topics: Animals; Biogenic Polyamines; Cell Cycle; Cell Division; Drug Combinations; Eflornithine; Estradiol;

1992
A prolactin-dependent, metastasising rat mammary carcinoma as a model for endocrine-related tumour dormancy.
    British journal of cancer, 1991, Volume: 64, Issue:3

    Topics: Animals; Bromocriptine; Cell Division; DNA, Neoplasm; Drug Implants; Estradiol; Female; Flow Cytomet

1991
Carcinoma induction following direct in situ transfer of v-Ha-ras into rat mammary epithelial cells using replication-defective retrovirus vectors.
    Cancer research, 1991, May-15, Volume: 51, Issue:10

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Epithelial Cells; Female; Genes, ras; Genetic V

1991
Hormonal control of polyamine pools in experimental breast cancer in vivo: correlation with estrogen and progesterone receptor levels.
    Breast cancer research and treatment, 1989, Volume: 14, Issue:2

    Topics: Animals; Estradiol; Female; Mammary Neoplasms, Experimental; Ovariectomy; Perphenazine; Prolactin; P

1989
Membranal tyrosine protein kinase activity (but not cAMP-dependent protein kinase activity) is associated with growth of rat mammary tumors.
    FEBS letters, 1985, Sep-09, Volume: 189, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiotensin II; Animals; Cell Division; Cyclic AMP; Female; Mammar

1985
Normal but not carcinomatous primary rat mammary epithelium: readily transplanted to and maintained in the athymic nude mouse.
    Journal of the National Cancer Institute, 1987, Volume: 78, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Epithelium; Estrogens; Female; Graft Survival; Mammary Gl

1987
Kinetic and morphometric responses of heterogeneous populations of experimental breast cancer cells in vivo.
    Cancer research, 1988, Jun-01, Volume: 48, Issue:11

    Topics: Animals; Cell Division; Estradiol; Female; Kinetics; Mammary Neoplasms, Experimental; Methylnitrosou

1988
Mammary tumor virus potentiation of endogenous prolactin effect on mammary gland differentiation.
    Journal of the National Cancer Institute, 1969, Volume: 42, Issue:2

    Topics: Animals; Estradiol; Factor Analysis, Statistical; Female; Genetics; Mammary Glands, Animal; Mammary

1969
The effect of perphenazine-induced serum prolactin response on estrogen-primed mammary tumor-host systems, 13762 and R-35 mammary adenocarcinomas.
    Cancer research, 1974, Volume: 34, Issue:11

    Topics: Adenocarcinoma; Animals; Cell Line; Dose-Response Relationship, Drug; Estradiol; Female; Mammary Gla

1974
Hormonal stimulation of lactose synthetase in mammary carcinoma.
    Science (New York, N.Y.), 1969, Sep-05, Volume: 165, Issue:3897

    Topics: Adenocarcinoma; Animals; Enzyme Induction; Female; Lactation; Lactose; Mammary Glands, Animal; Mamma

1969