perphenazine has been researched along with Emesis, Postoperative in 18 studies
Perphenazine: An antipsychotic phenothiazine derivative with actions and uses similar to those of CHLORPROMAZINE.
perphenazine : A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10.
| Excerpt | Relevance | Reference |
|---|---|---|
| "despite the introduction of newer antiemetics in the prevention of postoperative nausea and vomiting (PONV), perphenazine is recommended in current guidelines, as the concept of multimodal management of PONV in high-risk patients requires more than two drugs to be combined." | 8.86 | Efficacy of perphenazine to prevent postoperative nausea and vomiting: a quantitative systematic review. ( Eberhart, LH; Kranke, P; Morin, AM; Muellenbach, R; Roewer, N; Schnabel, A, 2010) |
| "despite the introduction of newer antiemetics in the prevention of postoperative nausea and vomiting (PONV), perphenazine is recommended in current guidelines, as the concept of multimodal management of PONV in high-risk patients requires more than two drugs to be combined." | 4.86 | Efficacy of perphenazine to prevent postoperative nausea and vomiting: a quantitative systematic review. ( Eberhart, LH; Kranke, P; Morin, AM; Muellenbach, R; Roewer, N; Schnabel, A, 2010) |
| "Perphenazine is a treatment option in postoperative nausea and vomiting (PONV) prophylaxis." | 3.80 | Extrapyramidal symptoms following administration of oral perphenazine 4 or 8 mg: an 11-year retrospective analysis. ( Henao, JP; Lichvar, AB; Orebaugh, SL; Peperzak, KA; Pippi, MA; Skledar, SJ; Williams, BA, 2014) |
| "PONV was defined as the need for rescue antiemetics on postoperative days (POD) 0-5." | 1.51 | Postoperative nausea and vomiting in patients undergoing colorectal surgery within an institutional enhanced recovery after surgery protocol: comparison of two prophylactic antiemetic regimens. ( Boisen, ML; Esper, SA; Gealey, J; Holder-Murray, J; Medich, DS; Meister, K; Subramaniam, K, 2019) |
| "To track the incidence of in-hospital postoperative nausea and vomiting (PONV) requiring postoperative parenteral nursing interventions after outpatient reconstruction of the anterior cruciate ligament (ACL) with one of two types of regional anesthesia to determine the extent to which various anesthetic techniques, preemptive antiemetics, and other factors were associated with the lowest probability of PONV." | 1.32 | Nausea and vomiting after outpatient ACL reconstruction with regional anesthesia: are lumbar plexus blocks a risk factor? ( Figallo, CM; Kelly, MD; Kentor, ML; Vogt, MT; Williams, BA; Williams, JP, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (38.89) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Williams, BA | 6 |
| Holder-Murray, JM | 1 |
| Esper, SA | 2 |
| Subramaniam, K | 2 |
| Skledar, SJ | 3 |
| Kentor, ML | 5 |
| Orebaugh, SL | 4 |
| Mangione, MP | 1 |
| Ibinson, JW | 1 |
| Waters, JH | 1 |
| Williams, JP | 2 |
| Chelly, JE | 1 |
| Holder-Murray, J | 1 |
| Boisen, ML | 1 |
| Gealey, J | 1 |
| Meister, K | 1 |
| Medich, DS | 1 |
| Henao, JP | 1 |
| Peperzak, KA | 1 |
| Lichvar, AB | 1 |
| Pippi, MA | 1 |
| Schnabel, A | 2 |
| Eberhart, LH | 2 |
| Muellenbach, R | 2 |
| Morin, AM | 2 |
| Roewer, N | 2 |
| Kranke, P | 2 |
| SCURR, CF | 1 |
| ROBBIE, DS | 1 |
| CONGER, CW | 1 |
| CLAASSEN, LG | 1 |
| HAMELBERG, W | 1 |
| LIND, B | 1 |
| CUTOLO, LC | 1 |
| KLEPPEL, NH | 1 |
| D'AGOSTINO, A | 1 |
| BONVINO, G | 1 |
| MUSETTO, CA | 1 |
| WARD, AJ | 1 |
| GOUVEIA, S | 1 |
| ROBERTS, H | 1 |
| Vogt, MT | 1 |
| Figallo, CM | 1 |
| Kelly, MD | 1 |
| Vallejo, MC | 1 |
| Fujii, Y | 2 |
| Saitoh, Y | 2 |
| Tanaka, H | 2 |
| Hidenori, T | 1 |
| Toyooka, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Opioid Free Versus Opioid Balanced Anesthesia in Middle Ear Surgery.[NCT03809949] | Phase 4 | 60 participants (Actual) | Interventional | 2019-01-16 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for perphenazine and Emesis, Postoperative
| Article | Year |
|---|---|
Efficacy of perphenazine to prevent postoperative nausea and vomiting: a quantitative systematic review.
Topics: Adult; Antiemetics; Child; Humans; Perphenazine; Postoperative Nausea and Vomiting; Randomized Contr | 2010 |
3 trials available for perphenazine and Emesis, Postoperative
14 other studies available for perphenazine and Emesis, Postoperative
| Article | Year |
|---|---|
Oral Perphenazine 8 mg: A Low-Cost, Efficacious Antiemetic Option.
Topics: Antiemetics; Humans; Perphenazine; Postoperative Nausea and Vomiting | 2021 |
Postoperative nausea and vomiting in patients undergoing colorectal surgery within an institutional enhanced recovery after surgery protocol: comparison of two prophylactic antiemetic regimens.
Topics: Adult; Aged; Antiemetics; Aprepitant; Digestive System Surgical Procedures; Enhanced Recovery After | 2019 |
Extrapyramidal symptoms following administration of oral perphenazine 4 or 8 mg: an 11-year retrospective analysis.
Topics: Administration, Oral; Adolescent; Adult; Ambulatory Surgical Procedures; Basal Ganglia Diseases; Dop | 2014 |
Post-operative nausea and vomiting prevention with perphenazine: long overdue.
Topics: Administration, Oral; Antiemetics; Drug Therapy, Combination; Humans; Ondansetron; Perphenazine; Pos | 2011 |
Providing effective implementation of antiemetic strategies: the postoperative nausea and vomiting-free hospital is a laudable and realistic goal.
Topics: Antiemetics; Humans; Perphenazine; Postoperative Nausea and Vomiting | 2011 |
Trials of perphenazine in the prevention of postoperative vomiting.
Topics: Biomedical Research; Perphenazine; Phenothiazines; Postoperative Nausea and Vomiting; Surgical Proce | 1958 |
Control of postoperative nausea and vomiting. A double blind study of perphenazine (Trilafon) in two hundred and thirty-six patients.
Topics: Double-Blind Method; Humans; Nausea; Perphenazine; Postoperative Care; Postoperative Nausea and Vomi | 1961 |
Control of postoperative vomiting with perphenazine (Trilafon). A double-blind study.
Topics: Biomedical Research; Double-Blind Method; Humans; Perphenazine; Postoperative Care; Postoperative Na | 1960 |
Effect of perphenazine on postoperative emesis.
Topics: Perphenazine; Postoperative Nausea and Vomiting; Surgical Procedures, Operative; Vomiting | 1959 |
[The use of perphenazine in treatment of postoperative vomiting].
Topics: Perphenazine; Postoperative Nausea and Vomiting; Surgical Procedures, Operative; Vomiting | 1960 |
Premedication for the control of postoperative vomiting.
Topics: Antiemetics; Humans; Perphenazine; Postoperative Nausea and Vomiting; Premedication | 1959 |
Postoperative nausea and vomiting: the response to anti-emetic drugs with special reference to cyclizine and perphenazine.
Topics: Anti-Allergic Agents; Antiemetics; Cyclizine; Histamine H1 Antagonists; Humans; Perphenazine; Postop | 1960 |
Nausea and vomiting after outpatient ACL reconstruction with regional anesthesia: are lumbar plexus blocks a risk factor?
Topics: Adult; Ambulatory Care; Anterior Cruciate Ligament; Antiemetics; Dexamethasone; Drug Therapy, Combin | 2004 |
Antiemetics in outpatient regional anesthesia for invasive orthopedic surgery.
Topics: Ambulatory Surgical Procedures; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Intravenous | 2005 |