perphenazine has been researched along with Catatonia in 20 studies
Perphenazine: An antipsychotic phenothiazine derivative with actions and uses similar to those of CHLORPROMAZINE.
perphenazine : A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10.
Catatonia: A neuropsychiatric disorder characterized by one or more of the following essential features: immobility, mutism, negativism (active or passive refusal to follow commands), mannerisms, stereotypies, posturing, grimacing, excitement, echolalia, echopraxia, muscular rigidity, and stupor; sometimes punctuated by sudden violent outbursts, panic, or hallucinations. This condition may be associated with psychiatric illnesses (e.g., SCHIZOPHRENIA; MOOD DISORDERS) or organic disorders (NEUROLEPTIC MALIGNANT SYNDROME; ENCEPHALITIS, etc.). (From DSM-IV, 4th ed, 1994; APA, Thesaurus of Psychological Index Terms, 1994)
| Excerpt | Relevance | Reference |
|---|---|---|
| " valproate) were studied in rats against perphenazine-induced catatonia." | 7.67 | GABAergic, dopaminergic and cholinergic interactions in perphenazine-induced catatonia in rats. ( Garg, SK; Kulkarni, SK; Mathur, VS; Shukla, VK, 1985) |
| " The catatonia was induced by perphenazine with a concomitant and remarkable increase in the brain histamine level." | 7.65 | The mechanism of the potentiating effect of antidepressant drugs on the protective influenc oe of diphenhydramine in experimental catatonia. The role of histamine. ( Chopra, YM; Dandiya, PC, 1974) |
| "The motor dysfunction (catatonia) could be easily assessed using rota-rod test apparatus in mice." | 5.31 | Role of adenosine in drug-induced catatonia in mice. ( Kulkarni, SK; Singh, A, 2002) |
| " Further, the protective effect of COX-inhibitors against perphenazine-induced catatonia and 1-methyl-4-phenyl-1, 2, 3, 6-tertahydropyridine (MPTP)-induced striatal lesions in rats was evaluated." | 3.75 | Protective effect of cyclooxygenase (COX)-inhibitors against drug-induced catatonia and MPTP-induced striatal lesions in rats. ( Dhir, A; Gupta, A; Kulkarni, SK; Kumar, A, 2009) |
| ") and intracerebroventricularly (5 micrograms/10 microliters/rat) administered clonidine was studied in rats against perphenazine-induced catatonia." | 3.67 | Anticatatonic effect of clonidine: its interaction with dopaminergic, anticholinergic and GABA-ergic drugs. ( Garg, SK; Kulkarni, SK; Shukla, VK, 1986) |
| " valproate) were studied in rats against perphenazine-induced catatonia." | 3.67 | GABAergic, dopaminergic and cholinergic interactions in perphenazine-induced catatonia in rats. ( Garg, SK; Kulkarni, SK; Mathur, VS; Shukla, VK, 1985) |
| "Administration of perphenazine, tremorine, nicotine and harmine induced Parkinson-like symptoms in rats and mice." | 3.66 | Modification of drug-induced catatonia and tremors by quapazine in rats and mice. ( Arzi, A; Kaul, PN; Kulkarni, SK, 1980) |
| " The ethers which result from this change have increased lipophilicity compared to their ability to inhibit perphenazine-induced catatonia in rats." | 3.65 | Synthesis and preliminary pharmacological activity of aminoalkoxy isosteres of glycolate ester anticholinergics. ( Amdrako, J; Fries, DS, 1977) |
| " The catatonia was induced by perphenazine with a concomitant and remarkable increase in the brain histamine level." | 3.65 | The mechanism of the potentiating effect of antidepressant drugs on the protective influenc oe of diphenhydramine in experimental catatonia. The role of histamine. ( Chopra, YM; Dandiya, PC, 1974) |
| "The motor dysfunction (catatonia) could be easily assessed using rota-rod test apparatus in mice." | 1.31 | Role of adenosine in drug-induced catatonia in mice. ( Kulkarni, SK; Singh, A, 2002) |
| "A woman with periodic catatonia had a 600-day metabolic study." | 1.25 | Longitudinal study of periodic catatonia. Long-term clinical and biochemical study of a woman with periodic catatonia. ( Cookson, BA; Huszka, L; Quarrington, B, 1967) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (85.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gupta, A | 1 |
| Dhir, A | 1 |
| Kumar, A | 1 |
| Kulkarni, SK | 6 |
| Cookson, BA | 1 |
| Quarrington, B | 1 |
| Huszka, L | 1 |
| Carroll, B | 1 |
| Yoho, SD | 1 |
| Bottoms, JM | 1 |
| Singh, A | 1 |
| HACHIYA, H | 1 |
| Arzi, A | 1 |
| Kaul, PN | 1 |
| Fries, DS | 1 |
| Amdrako, J | 1 |
| Angst, J | 1 |
| Woggon, B | 1 |
| Chopra, YM | 2 |
| Dandiya, PC | 3 |
| Aley, KO | 1 |
| Shukla, VK | 2 |
| Garg, SK | 2 |
| Mathur, VS | 1 |
| Pollet, P | 1 |
| Patni, SK | 1 |
| Rodová, A | 2 |
| Svestka, J | 2 |
| Náhunek, K | 2 |
| Cesková, E | 1 |
| Mori, J | 1 |
| Sato, Y | 1 |
| Oashi, T | 1 |
| Hitomi, M | 1 |
| Uno, M | 1 |
| Smulevich, AB | 1 |
| Golovan', LI | 1 |
| Sokolova, ED | 1 |
| Tsutsul'kovskaia, MIa | 1 |
1 review available for perphenazine and Catatonia
| Article | Year |
|---|---|
[Contribution to the study of experimental catatonia in guinea pigs. Effect of various psychoactive drugs on this phenomenon].
Topics: Animals; Catatonia; Chlorpromazine; Female; Guinea Pigs; Haloperidol; Male; Meprobamate; Perphenazin | 1967 |
2 trials available for perphenazine and Catatonia
| Article | Year |
|---|---|
[Clinical study on five depot neuroleptics. Comparison of effective profiles of fluphenazinedecanoate, fluspirilene, penfluridol, perphenazine-enanthate and pipothiazinepalmitate].
Topics: Administration, Oral; Bipolar Disorder; Catatonia; Clinical Trials as Topic; Delayed-Action Preparat | 1975 |
Comparison of the therapeutic results of clothiapin and perphenazine in schizophrenia.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Catatonia; Clinical Trials as Topic; Dibenzothiazepines; | 1971 |
17 other studies available for perphenazine and Catatonia
| Article | Year |
|---|---|
Protective effect of cyclooxygenase (COX)-inhibitors against drug-induced catatonia and MPTP-induced striatal lesions in rats.
Topics: Animals; Catatonia; Corpus Striatum; Cyclooxygenase Inhibitors; Male; Motor Activity; MPTP Poisoning | 2009 |
Longitudinal study of periodic catatonia. Long-term clinical and biochemical study of a woman with periodic catatonia.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Antipsychotic Agents; Blood Pressure; Body Temperature; | 1967 |
Periodic catatonia.
Topics: Anticonvulsants; Antipsychotic Agents; Catatonia; Comorbidity; Drug Resistance; Drug Therapy, Combin | 2011 |
Role of adenosine in drug-induced catatonia in mice.
Topics: Adenosine; Animals; Antiparkinson Agents; Brain; Carbidopa; Catatonia; Catechol O-Methyltransferase | 2002 |
[PHARMACOTHERAPY OF SCHIZOPHRENIA. I. PHARMACOTHERAPY WITH IN-PATIENTS OF SHORT-TERM ADMISSION].
Topics: Adolescent; Catatonia; Child; Chlorpromazine; Convulsive Therapy; Electroconvulsive Therapy; Humans; | 1964 |
Modification of drug-induced catatonia and tremors by quapazine in rats and mice.
Topics: Animals; Antiparkinson Agents; Catatonia; Drug Combinations; Drug Interactions; Harmine; Humans; Mal | 1980 |
Synthesis and preliminary pharmacological activity of aminoalkoxy isosteres of glycolate ester anticholinergics.
Topics: Animals; Body Temperature; Catatonia; Chemistry, Pharmaceutical; Glycolates; Humans; In Vitro Techni | 1977 |
The relative role of brain acetylcholine and histamine in perphenazine catatonia and influence of antidepressants and diphenhydramine alone and in combination.
Topics: Acetylcholine; Animals; Antidepressive Agents; Brain; Brain Chemistry; Catatonia; Diphenhydramine; D | 1975 |
Anticatatonic effect of venoruton.
Topics: Animals; Anticoagulants; Antipsychotic Agents; Catatonia; Female; Haloperidol; Hydroxyethylrutoside; | 1988 |
Anticatatonic effect of clonidine: its interaction with dopaminergic, anticholinergic and GABA-ergic drugs.
Topics: Animals; Catatonia; Clonidine; Drug Interactions; Injections, Intraventricular; Male; Parasympatholy | 1986 |
GABAergic, dopaminergic and cholinergic interactions in perphenazine-induced catatonia in rats.
Topics: Animals; Bromocriptine; Catatonia; Dopamine; Drug Synergism; GABA Antagonists; gamma-Aminobutyric Ac | 1985 |
The mechanism of the potentiating effect of antidepressant drugs on the protective influenc oe of diphenhydramine in experimental catatonia. The role of histamine.
Topics: Animals; Antidepressive Agents; Brain; Brain Chemistry; Catatonia; Diphenhydramine; Drug Synergism; | 1974 |
The influence of monoamine oxidase inhibitors and some other antidepressants on the anti-parkinsonian activity of sub-effective doses of diphenylhydramine in rats and mice.
Topics: Animals; Antidepressive Agents; Catatonia; Diphenhydramine; Humans; Mice; Monoamine Oxidase Inhibito | 1972 |
A blind comparison of clozapine and perphenazine in schizophrenics.
Topics: Adult; Catatonia; Dibenzothiepins; Female; Humans; Male; Perphenazine; Schizophrenia; Schizophrenia, | 1973 |
[Pharmacological study of amantadine, a new antiparkinson drug].
Topics: Amantadine; Amines; Animals; Antiparkinson Agents; Avoidance Learning; Brain; Catatonia; Dopamine; D | 1974 |
[Follow-up studies of schizophrenia].
Topics: Adult; Catalepsy; Catatonia; Chlorpromazine; Chronic Disease; Convulsive Therapy; Depersonalization; | 1971 |
[On the problem of the general and elective action of psycholeptics in the therapy of schizophrenia].
Topics: Catatonia; Chlordiazepoxide; Chlorpromazine; Haloperidol; Humans; Paranoid Disorders; Perphenazine; | 1968 |