perphenazine has been researched along with Body Weight in 18 studies
Perphenazine: An antipsychotic phenothiazine derivative with actions and uses similar to those of CHLORPROMAZINE.
perphenazine : A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The goal of the study was to characterize population pharmacokinetics (PPK) for perphenazine in patients with schizophrenia from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE)." | 9.14 | Population pharmacokinetics of perphenazine in schizophrenia patients from CATIE: impact of race and smoking. ( Bies, RR; Coley, K; Florian, J; Jin, Y; Kirshner, M; Lieberman, J; Marder, SR; Miller, D; Pollock, BG; Schneider, L, 2010) |
| "The goal of the study was to characterize population pharmacokinetics (PPK) for perphenazine in patients with schizophrenia from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE)." | 5.14 | Population pharmacokinetics of perphenazine in schizophrenia patients from CATIE: impact of race and smoking. ( Bies, RR; Coley, K; Florian, J; Jin, Y; Kirshner, M; Lieberman, J; Marder, SR; Miller, D; Pollock, BG; Schneider, L, 2010) |
| " Perphenazine-induced PRL release in normal mice and in GTG-injected non-obese mice was compared to that of GTG-injected obese mice after the initial development of obesity, after body weight reduction by diet control and after the resumption of obesity by ad lib." | 3.65 | Control of prolactin and growth hormone secretion in mice by obesity. ( Salocks, CB; Sinha, YN; Vanderlaan, WP, 1976) |
| " LD50 values calculated in rats were 2000 mg/kg and 325 mg/kg, after p." | 1.29 | Acute and chronic toxicity of "Polfa" perphenazine. ( Chibowski, D; Kleinrok, Z; Rajtar, G; Sieklucka-Dziuba, M; Siezieniewska, Z, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (83.33) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jin, Y | 1 |
| Pollock, BG | 1 |
| Coley, K | 1 |
| Miller, D | 1 |
| Marder, SR | 1 |
| Florian, J | 1 |
| Schneider, L | 1 |
| Lieberman, J | 1 |
| Kirshner, M | 1 |
| Bies, RR | 1 |
| Swartz, MS | 1 |
| Clinton, SK | 1 |
| Mulloy, AL | 1 |
| Visek, WJ | 1 |
| Greeley, GH | 1 |
| Lipton, MA | 1 |
| Kizer, JS | 1 |
| Muller, E | 1 |
| Dowling, RH | 1 |
| Redmond, GP | 1 |
| Hirshman, MF | 1 |
| Kleinrok, Z | 1 |
| Sieklucka-Dziuba, M | 1 |
| Rajtar, G | 1 |
| Chibowski, D | 1 |
| Siezieniewska, Z | 1 |
| Szabo, KT | 1 |
| Brent, RL | 1 |
| Gralla, EJ | 1 |
| Sabo, JP | 1 |
| Hayden, DW | 1 |
| Yochmowitz, MG | 1 |
| Mattsson, JL | 1 |
| Prusoff, BA | 1 |
| Williams, DH | 1 |
| Weissman, MM | 1 |
| Astrachan, BM | 1 |
| Korsgaard, S | 1 |
| Skausig, OB | 1 |
| Sinha, YN | 3 |
| Wolff, GL | 1 |
| Baxter, SR | 1 |
| Domon, OE | 1 |
| Salocks, CB | 2 |
| Vanderlaan, WP | 2 |
| Thomas, JW | 1 |
| Wickes, MA | 1 |
| Hoshi, K | 1 |
| Senda, N | 1 |
| Fujino, S | 1 |
| Collins, AD | 1 |
| Dundas, J | 1 |
| Kingstone, E | 1 |
| Kolivakis, T | 1 |
| Kossatz, I | 1 |
| Ben-David, M | 1 |
4 trials available for perphenazine and Body Weight
| Article | Year |
|---|---|
Population pharmacokinetics of perphenazine in schizophrenia patients from CATIE: impact of race and smoking.
Topics: Adolescent; Adult; Age Factors; Aged; Antipsychotic Agents; Body Weight; Dose-Response Relationship, | 2010 |
Treatment of secondary depression in schizophrenia. A double-blind, placebo-controlled trial of amitriptyline added to perphenazine.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Amitriptyline; Blood Pressure; Body Weight; Chronic Diseas | 1979 |
A double-blind trial of amitriptyline/perphenazine, perphenazine and placebo in chronic withdrawn inert schizophrenics.
Topics: Adult; Affect; Amitriptyline; Analysis of Variance; Body Weight; Chronic Disease; Clinical Trials as | 1967 |
Double blind study of clopenthixol and chlorpromazine in acute hospitalized schizophrenics.
Topics: Acute Disease; Adolescent; Adult; Aged; Aspartate Aminotransferases; Blood Pressure; Body Weight; Ch | 1970 |
14 other studies available for perphenazine and Body Weight
| Article | Year |
|---|---|
Introduction to the CATIE special section.
Topics: Antipsychotic Agents; Body Weight; Clinical Trials as Topic; Clozapine; Cognition; Health Policy; Hu | 2008 |
Effects of dietary lipid saturation on prolactin secretion, carcinogen metabolism and mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Dietary Fats; Female; Mammary N | 1984 |
Effects of chronic perphenazine treatment on growth and endocrine function in developing rats.
Topics: Animals; Body Weight; Endocrine Glands; Estrus; Female; Gonadotropin-Releasing Hormone; Growth; Horm | 1982 |
Prolactin and the small intestine. Effect of hyperprolactinaemia on mucosal structure in the rat.
Topics: Animals; Body Weight; Female; Intestinal Mucosa; Intestine, Small; Lactation; Perphenazine; Pituitar | 1981 |
Postnatal growth retardation in rats produced by the phenothiazine perphenazine.
Topics: Animals; Body Weight; Eating; Growth Disorders; Male; Perphenazine; Rats; Rats, Inbred Strains; Tail | 1980 |
Acute and chronic toxicity of "Polfa" perphenazine.
Topics: Animals; Body Weight; Lethal Dose 50; Male; Motor Activity; Organ Size; Perphenazine; Rats; Rats, Wi | 1994 |
Letter: Reduction of drug-induced cleft palate in mice.
Topics: Animals; Body Weight; Cleft Palate; Feeding Behavior; Female; Food Deprivation; Haloperidol; Materna | 1975 |
The effect of selected drugs on first-stage radioemesis in beagle dogs.
Topics: Amifostine; Amphetamine; Animals; Antiemetics; Body Weight; Chlorpromazine; Dimenhydrinate; Diphenhy | 1979 |
Increase in weight after treatment with depot neuroleptics.
Topics: Administration, Oral; Body Weight; Clopenthixol; Delayed-Action Preparations; Drug Implants; Female; | 1979 |
Serum and pituitary concentrations of growth hormone and prolactin in pygmy mice.
Topics: Animals; Body Weight; Female; Growth Disorders; Growth Hormone; Male; Mice; Perphenazine; Pituitary | 1979 |
Control of prolactin and growth hormone secretion in mice by obesity.
Topics: Animals; Aurothioglucose; Body Weight; Female; Growth Hormone; Mice; Mice, Inbred Strains; Obesity; | 1976 |
Prolactin and growth hormone secretion in diet-induced obesity in mice.
Topics: Animals; Body Weight; Diet; Dietary Fats; Female; Growth Hormone; Male; Mice; Mice, Inbred C3H; Mice | 1977 |
Effects of perphenazine, diazepam and nitrazepam on amitriptyline metabolism in rat.
Topics: Amitriptyline; Animals; Body Weight; Diazepam; Glucuronosyltransferase; Male; Microsomes, Liver; Nit | 1988 |
Role of the ovaries in perphenazine-induced lactation.
Topics: Animals; Body Weight; DNA; Estradiol; Female; Lactation; Mammary Glands, Animal; Organ Size; Ovary; | 1968 |