perphenazine has been researched along with Atherosclerotic Parkinsonism in 17 studies
Perphenazine: An antipsychotic phenothiazine derivative with actions and uses similar to those of CHLORPROMAZINE.
perphenazine : A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Perphenazine level was not correlated with EPS; but benztropine, given only if required for serious EPS, was more likely to be used when perphenazine levels were elevated." | 2.67 | The relationship between blood perphenazine levels, early resolution of psychotic symptoms, and side effects. ( Bowers, MB; Jatlow, PI; Kincare, P; Mazure, CM; Nelson, JC, 1990) |
| " Improvement was recorded in a double blind study of 18 patients treated with maximum tolerated dosage (mean 18." | 2.64 | Tardive dyskinesia treated with pimozide. ( Calne, DB; Claveria, LE; Haskayne, L; Lodge-Patch, IC; Pallis, CA; Petrie, A; Teychenne, PF, 1975) |
| "Haloperidol was implicated in 47 patients (37%), followed by amitriptyline/perphenazine in 30%, thioridazine in 27%, and chlorpromazine in 20%." | 1.28 | Neurologic approach to drug-induced movement disorders: a study of 125 patients. ( Jankovic, J; Miller, LG, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (70.59) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sheppard, C | 1 |
| Merlis, S | 1 |
| Verma, A | 1 |
| Kulkarni, SK | 1 |
| Høyberg, OJ | 1 |
| Fensbo, C | 1 |
| Remvig, J | 1 |
| Lingjaerde, O | 1 |
| Sloth-Nielsen, M | 1 |
| Salvesen, I | 1 |
| Sweet, RA | 1 |
| Pollock, BG | 1 |
| Mulsant, BH | 1 |
| Rosen, J | 1 |
| Lo, KH | 1 |
| Yao, JK | 1 |
| Henteleff, RA | 1 |
| Mazumdar, S | 1 |
| Claveria, LE | 1 |
| Teychenne, PF | 1 |
| Calne, DB | 1 |
| Haskayne, L | 1 |
| Petrie, A | 1 |
| Pallis, CA | 1 |
| Lodge-Patch, IC | 1 |
| Lutz, EG | 1 |
| Miller, LG | 1 |
| Jankovic, J | 1 |
| Mazure, CM | 1 |
| Nelson, JC | 1 |
| Jatlow, PI | 1 |
| Kincare, P | 1 |
| Bowers, MB | 1 |
| Bruck, H | 1 |
| Gerstenbrand, F | 1 |
| Gnad, H | 1 |
| Gründig, E | 1 |
| Prosenz, P | 1 |
| Patni, SK | 1 |
| Dandiya, PC | 2 |
| Kingstone, E | 1 |
| Kolivakis, T | 1 |
| Kossatz, I | 1 |
| Haddenbrock, S | 1 |
| Demars, JP | 1 |
| Nahunek, K | 1 |
| Svestka, J | 1 |
| Rodová, A | 1 |
| Bhargava, LP | 1 |
| Ekdawi, MY | 1 |
| Fowke, R | 1 |
7 trials available for perphenazine and Atherosclerotic Parkinsonism
| Article | Year |
|---|---|
Risperidone versus perphenazine in the treatment of chronic schizophrenic patients with acute exacerbations.
Topics: Acute Disease; Adult; Aged; Antipsychotic Agents; Denmark; Double-Blind Method; Female; Humans; Isox | 1993 |
Association of plasma homovanillic acid with behavioral symptoms in patients diagnosed with dementia: a preliminary report.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antipsychotic Agents; Behavior; Dyskinesia, Drug-Induced | 1997 |
Tardive dyskinesia treated with pimozide.
Topics: Aged; Antipsychotic Agents; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Consciousnes | 1975 |
The relationship between blood perphenazine levels, early resolution of psychotic symptoms, and side effects.
Topics: Adult; Akathisia, Drug-Induced; Basal Ganglia Diseases; Benztropine; Clinical Trials as Topic; Dose- | 1990 |
Effect of different neuroleptics in tardive dyskinesia and parkinsonism. A video-controlled multicenter study with chlorprothixene, perphenazine, haloperidol and haloperidol + biperiden. Nordic Dyskinesia Study Group.
Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Biperiden; Chlorprothixene; Dyskinesia, Drug-I | 1986 |
Double blind study of clopenthixol and chlorpromazine in acute hospitalized schizophrenics.
Topics: Acute Disease; Adolescent; Adult; Aged; Aspartate Aminotransferases; Blood Pressure; Body Weight; Ch | 1970 |
Neuromuscular effects of long-term phenothiazine medication, electroconvulsive therapy and leucotomy.
Topics: Aged; Chlorpromazine; Clinical Trials as Topic; Electric Stimulation Therapy; Female; Haloperidol; H | 1966 |
10 other studies available for perphenazine and Atherosclerotic Parkinsonism
| Article | Year |
|---|---|
Drug-induced extrapyramidal symptoms: their incidence and treatment.
Topics: Chlorpromazine; Chlorprothixene; Extrapyramidal Tracts; Female; Fluphenazine; Humans; Male; Parasymp | 1967 |
N-Methyl-D-aspartate receptor participation in Parkinson's disease, a neurodegenerative disorder.
Topics: Animals; Antiparkinson Agents; Apomorphine; Benzazepines; Catalepsy; Dizocilpine Maleate; Haloperido | 1995 |
Neuroleptic-induced parkinsonism facilitated by alcohol.
Topics: Amitriptyline; Drug Synergism; Ethanol; Female; Humans; Middle Aged; Parkinson Disease, Secondary; P | 1978 |
Neurologic approach to drug-induced movement disorders: a study of 125 patients.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Amitriptyline; Antipsychotic Agents; Chorea | 1990 |
[Comparative biochemical studies in organic parkinsonian syndromes and drug induced parkinsonian syndromes].
Topics: Alanine Transaminase; Aspartate Aminotransferases; Biochemical Phenomena; Biochemistry; Chlorpromazi | 1966 |
The influence of monoamine oxidase inhibitors and some other antidepressants on the anti-parkinsonian activity of sub-effective doses of diphenylhydramine in rats and mice.
Topics: Animals; Antidepressive Agents; Catatonia; Diphenhydramine; Humans; Mice; Monoamine Oxidase Inhibito | 1972 |
[On the mode of action and the question of central organic late damages of continuous neuroleptic treatment].
Topics: Aged; Brain Stem; Butyrophenones; Central Nervous System; Cerebral Ventriculography; Extrapyramidal | 1966 |
Further clinical experience with octoclothepin.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Dibenzothiepins; Female; Humans; Male; Middle Aged; Parki | 1970 |
The antiparkinsonian activity of monoamine oxidase inhibitors and other agents in rats and mice.
Topics: Animals; Dextroamphetamine; Diphenhydramine; Imipramine; Iproniazid; Isocarboxazid; Mice; Monoamine | 1968 |
A controlled trial of anti-Parkinson drugs in drug-induced Parkinsonism.
Topics: Adolescent; Adult; Chlorpromazine; Haloperidol; Humans; Middle Aged; Orphenadrine; Parasympatholytic | 1966 |