perphenazine has been researched along with Amyotrophic Lateral Sclerosis in 1 studies
Perphenazine: An antipsychotic phenothiazine derivative with actions and uses similar to those of CHLORPROMAZINE.
perphenazine : A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Seredenina, T | 1 |
| Nayernia, Z | 1 |
| Sorce, S | 1 |
| Maghzal, GJ | 1 |
| Filippova, A | 1 |
| Ling, SC | 1 |
| Basset, O | 1 |
| Plastre, O | 1 |
| Daali, Y | 1 |
| Rushing, EJ | 1 |
| Giordana, MT | 1 |
| Cleveland, DW | 1 |
| Aguzzi, A | 1 |
| Stocker, R | 1 |
| Krause, KH | 1 |
| Jaquet, V | 1 |
1 other study available for perphenazine and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Female; Gene Expression | 2016 |