perphenazine has been researched along with Amentia in 9 studies
Perphenazine: An antipsychotic phenothiazine derivative with actions and uses similar to those of CHLORPROMAZINE.
perphenazine : A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study of 45 elderly patients suffering from dementia and treated with perphenazine, 5 patients who were prospectively identified as poor P450 2D6 metabolizers had significantly greater side effects than the 40 extensive metabolizers." | 3.69 | Prospective cytochrome P450 phenotyping for neuroleptic treatment in dementia. ( Altieri, LP; Mulsant, BH; Perel, JM; Pollock, BG; Rosen, J; Sweet, RA, 1995) |
| "Citalopram was found to be more efficacious than placebo in the short-term hospital treatment of psychotic symptoms and behavioral disturbances in nondepressed, demented patients." | 2.70 | Comparison of citalopram, perphenazine, and placebo for the acute treatment of psychosis and behavioral disturbances in hospitalized, demented patients. ( Bharucha, A; Chew, ML; Huber, KA; Jacob, NJ; Kastango, KB; Marin, R; Mazumdar, S; Mulsant, BH; Pollock, BG; Rosen, J; Sweet, RA, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| AYD, FJ | 1 |
| ANDERSEN, E | 1 |
| HANSEN, G | 1 |
| SOULAIRAC, A | 1 |
| GEIER, S | 1 |
| MOREL, P | 1 |
| FILLIOZAT, AM | 1 |
| FILLIOZAT, R | 1 |
| CHAVANNES, N | 1 |
| Bourgeois, M | 1 |
| Pollock, BG | 3 |
| Mulsant, BH | 3 |
| Sweet, RA | 3 |
| Rosen, J | 3 |
| Altieri, LP | 1 |
| Perel, JM | 1 |
| Sorisio, D | 1 |
| Kirshner, M | 1 |
| Henteleff, R | 1 |
| DeMichele, MA | 1 |
| Mazumdar, S | 1 |
| Bharucha, A | 1 |
| Marin, R | 1 |
| Jacob, NJ | 1 |
| Huber, KA | 1 |
| Kastango, KB | 1 |
| Chew, ML | 1 |
| Kamen, S | 1 |
| Radzuweit, H | 1 |
| Knorr, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Continuation Pharmacotherapy for Agitation of Dementia[NCT00073658] | Phase 2 | 137 participants | Interventional | 2000-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for perphenazine and Amentia
| Article | Year |
|---|---|
Comparison of citalopram, perphenazine, and placebo for the acute treatment of psychosis and behavioral disturbances in hospitalized, demented patients.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Behavioral Symptoms; Citalopram; Dementia; Donepezil; | 2002 |
8 other studies available for perphenazine and Amentia
| Article | Year |
|---|---|
The treatment of anxiety, agitation and excitement in the aged; a preliminary report on trilafon.
Topics: Aged; Anxiety; Dementia; Humans; Mental Disorders; Perphenazine; Psychomotor Agitation; Psychotic Di | 1957 |
[Trilafon & states of excitement in aged psychotics].
Topics: Dementia; Humans; Mental Disorders; Perphenazine; Phenothiazines; Psychotic Disorders | 1958 |
[A neuroleptic derivative of phenothiazine: perphenazine].
Topics: Alcoholism; Antipsychotic Agents; Character; Delusions; Dementia; Humans; Perphenazine; Phenothiazin | 1963 |
[Study of an antidepressive agent in psychiatry: Mutabon F].
Topics: Adjustment Disorders; Adolescent; Adult; Aged; Amitriptyline; Anxiety Disorders; Bipolar Disorder; D | 1967 |
Prospective cytochrome P450 phenotyping for neuroleptic treatment in dementia.
Topics: Aged; Alzheimer Disease; Cytochrome P-450 Enzyme System; Dementia; Female; Humans; Male; Middle Aged | 1995 |
Pharmacologic profile of perphenazine's metabolites.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Biotransformation; Brain; Cell Line, Transformed; Cyt | 2000 |
Tardive dyskinesia. A significant syndrome for geriatric dentistry.
Topics: Aged; Arteriosclerosis; Bruxism; Chlorpromazine; Dementia; Denture, Complete; Depression; Depressive | 1975 |
[Influencing of biological and immunologic pregnancy reactions by psychotropic drugs].
Topics: Adolescent; Adult; Aged; Butyrophenones; Chlorpromazine; Dementia; Depressive Disorder, Major; Dysau | 1969 |