Page last updated: 2024-09-03

peroxynitrous acid and Spinal Cord Injuries

peroxynitrous acid has been researched along with Spinal Cord Injuries in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's15 (78.95)29.6817
2010's4 (21.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Coyoy-Salgado, A; Feria-Romero, IA; Gallardo, JM; Guerra-Araiza, C; Orozco-Barrios, CE; Orozco-Suárez, S; Salgado-Ceballos, H; Segura-Uribe, JJ1
Dhammu, TS; Khan, M; Singh, AK; Singh, I1
Barnes, S; Basso, M; Beal, MF; Beckman, JS; Calingasan, NY; Estévez, AG; Feldman, JL; Franco, MC; Grumet, M; Kiaei, M; Ma, TC; Mehl, R; Melero Fernández de Mera, RM; Refakis, CA; Rhoads, TW; Sparrow, NA; Stokes, AL; Ye, Y1
Ashki, N; Bao, F; Hayes, KC1
Hall, ED; Xiong, Y1
Bramanti, P; Cuzzocrea, S; Di Paola, R; Esposito, E; Genovese, T; Mazzon, E; Murthy, K; Neville, L1
Langer, R; Neeley, WL; Pritchard, CD; Slotkin, JR; Teng, YD; Woodard, EJ; Yu, D1
Carrico, KM; Hall, ED; Vaishnav, R1
Hall, ED1
Bao, F; Liu, D2
Bao, F; DeWitt, DS; Liu, D; Prough, DS2
Hooper, DC; Scott, GS; Szabó, C; Virág, L1
Cuzzocrea, S; Genovese, T; Hooper, DC; Koprowski, H; Scott, GS1
Bramanti, P; Cannavò, G; Cuzzocrea, S; Di Paola, R; Genovese, T; Mazzon, E; Muià, C1
Hall, ED; Rabchevsky, AG; Xiong, Y1
Bramanti, P; Cuzzocrea, S; Di Paola, R; Esposito, E; Genovese, T; Mazzon, E; Muià, C1
Cuzzocrea, S; Genovese, T1

Reviews

3 review(s) available for peroxynitrous acid and Spinal Cord Injuries

ArticleYear
The Importance of Natural Antioxidants in the Treatment of Spinal Cord Injury in Animal Models: An Overview.
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Drugs, Chinese Herbal; Lipid Peroxidation; Medicine, Chinese Traditional; Mice; Neuroprotective Agents; Oxidative Stress; Peroxynitrous Acid; Primates; Rats; Spinal Cord Injuries

2019
Antioxidant therapies for acute spinal cord injury.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2011, Volume: 8, Issue:2

    Topics: Acute Disease; Animals; Antioxidants; Free Radicals; Humans; Lipid Peroxidation; Peroxynitrous Acid; Spinal Cord Injuries

2011
Role of free radicals and poly(ADP-ribose)polymerase-1 in the development of spinal cord injury: new potential therapeutic targets.
    Current medicinal chemistry, 2008, Volume: 15, Issue:5

    Topics: Animals; Free Radicals; Glutathione; Glycoside Hydrolases; Humans; Metalloporphyrins; Peroxynitrous Acid; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Spinal Cord Injuries; Superoxide Dismutase

2008

Other Studies

16 other study(ies) available for peroxynitrous acid and Spinal Cord Injuries

ArticleYear
Amelioration of spinal cord injury in rats by blocking peroxynitrite/calpain activity.
    BMC neuroscience, 2018, 08-13, Volume: 19, Issue:1

    Topics: Animals; Brain; Calpain; Disease Models, Animal; Male; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type I; Nitrosoguanidines; Peroxynitrous Acid; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries

2018
Nitration of Hsp90 induces cell death.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Mar-19, Volume: 110, Issue:12

    Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Death; Disease Models, Animal; fas Receptor; HSP90 Heat-Shock Proteins; Humans; Motor Neurons; Peroxynitrous Acid; Protein Processing, Post-Translational; Rats; Spinal Cord Injuries; Tyrosine

2013
The peroxynitrite donor 3-morpholinosydnonimine induces reversible changes in electrophysiological properties of neurons of the guinea-pig spinal cord.
    Neuroscience, 2008, Sep-22, Volume: 156, Issue:1

    Topics: Action Potentials; Animals; Axons; Cell Membrane; Dose-Response Relationship, Drug; Extracellular Fluid; Female; Guinea Pigs; Molsidomine; Nerve Degeneration; Neural Conduction; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitro Compounds; Peroxynitrous Acid; Sodium Channels; Spinal Cord; Spinal Cord Injuries; Tyrosine

2008
Pharmacological evidence for a role of peroxynitrite in the pathophysiology of spinal cord injury.
    Experimental neurology, 2009, Volume: 216, Issue:1

    Topics: Animals; Antioxidants; Calcium Signaling; Calpain; Cell Respiration; Cyclic N-Oxides; Disease Models, Animal; Drug Administration Schedule; Female; Free Radicals; Lipid Peroxidation; Mitochondria; Nerve Degeneration; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Spectrin; Spin Labels; Spinal Cord; Spinal Cord Injuries

2009
Effects of a metalloporphyrinic peroxynitrite decomposition catalyst, ww-85, in a mouse model of spinal cord injury.
    Free radical research, 2009, Volume: 43, Issue:7

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cytokines; Disease Models, Animal; Immunoenzyme Techniques; In Situ Nick-End Labeling; Lipid Peroxidation; Male; Mice; Motor Activity; Neutrophil Infiltration; NF-kappa B; Peroxidase; Peroxynitrous Acid; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Spinal Cord Injuries; Thiobarbituric Acid Reactive Substances; Tyrosine

2009
Blockade of peroxynitrite-induced neural stem cell death in the acutely injured spinal cord by drug-releasing polymer.
    Stem cells (Dayton, Ohio), 2009, Volume: 27, Issue:5

    Topics: Acute Disease; Animals; Annexin A5; Blotting, Western; Caspases; Cell Death; Cell Line; Cytoprotection; Drug Delivery Systems; Enzyme Activation; Fluoresceins; Free Radical Scavengers; Glycolates; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Lactic Acid; Neurons; Nitric Oxide; Peroxynitrous Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Signal Transduction; Spinal Cord Injuries; Stem Cells; Tyrosine

2009
Temporal and spatial dynamics of peroxynitrite-induced oxidative damage after spinal cord contusion injury.
    Journal of neurotrauma, 2009, Volume: 26, Issue:8

    Topics: Aldehydes; Animals; Female; Immunohistochemistry; Lipid Peroxidation; Neurons; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Thoracic Vertebrae; Time Factors; Tyrosine

2009
Peroxynitrite generated in the rat spinal cord induces neuron death and neurological deficits.
    Neuroscience, 2002, Volume: 115, Issue:3

    Topics: Animals; Cell Death; Dyskinesia, Drug-Induced; Male; Microdialysis; Molsidomine; Nerve Degeneration; Neurons; Nitric Oxide Donors; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries

2002
Peroxynitrite generated in the rat spinal cord induces oxidation and nitration of proteins: reduction by Mn (III) tetrakis (4-benzoic acid) porphyrin.
    Journal of neuroscience research, 2003, Jan-15, Volume: 71, Issue:2

    Topics: 2,4-Dinitrophenol; Animals; Drug Interactions; Enzyme Inhibitors; Free Radical Scavengers; Immunohistochemistry; Male; Metalloporphyrins; Microdialysis; Molsidomine; Neurons; Oxidation-Reduction; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Time Factors; Tyrosine

2003
Peroxynitrite-induced oligodendrocyte toxicity is not dependent on poly(ADP-ribose) polymerase activation.
    Glia, 2003, Jan-15, Volume: 41, Issue:2

    Topics: Animals; Cell Death; Cells, Cultured; Central Nervous System; Dose-Response Relationship, Drug; Female; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Multiple Sclerosis; Myelin Sheath; Oligodendroglia; Peroxynitrous Acid; Poly(ADP-ribose) Polymerases; Spinal Cord Injuries

2003
Peroxynitrite generated in the rat spinal cord induces apoptotic cell death and activates caspase-3.
    Neuroscience, 2003, Volume: 116, Issue:1

    Topics: Animals; Apoptosis; Caspase 3; Caspases; DNA Fragmentation; Immunohistochemistry; In Situ Nick-End Labeling; Male; Microdialysis; Microscopy, Electron; Molsidomine; Nitric Oxide Donors; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries

2003
Uric acid protects against secondary damage after spinal cord injury.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Mar-01, Volume: 102, Issue:9

    Topics: Animals; Cells, Cultured; Immunohistochemistry; Lipid Peroxidation; Male; Mice; Neurons; Neutrophils; Peroxidase; Peroxynitrous Acid; Spinal Cord Injuries; Uric Acid

2005
Role of endogenous ligands for the peroxisome proliferators activated receptors alpha in the secondary damage in experimental spinal cord trauma.
    Experimental neurology, 2005, Volume: 194, Issue:1

    Topics: Age Factors; Animals; Apoptosis; Disease Models, Animal; Ligands; Mice; Mice, Inbred C57BL; Mice, Knockout; Myelin Sheath; Neutrophils; Peroxynitrous Acid; PPAR alpha; Severity of Illness Index; Spinal Cord; Spinal Cord Injuries; Tumor Necrosis Factor-alpha

2005
Peroxynitrite generated at the level produced by spinal cord injury induces peroxidation of membrane phospholipids in normal rat cord: reduction by a metalloporphyrin.
    Journal of neurotrauma, 2005, Volume: 22, Issue:10

    Topics: Aldehydes; Animals; Cell Membrane; Free Radical Scavengers; Lipid Peroxidation; Male; Malondialdehyde; Metalloporphyrins; Molsidomine; Nitric Oxide Donors; Peroxynitrous Acid; Phospholipids; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries

2005
Role of peroxynitrite in secondary oxidative damage after spinal cord injury.
    Journal of neurochemistry, 2007, Volume: 100, Issue:3

    Topics: Aldehydes; Animals; Biomarkers; Calcium Signaling; Calpain; Disease Progression; Female; Free Radical Scavengers; Free Radicals; Lipid Peroxidation; Nerve Degeneration; Nitric Oxide; Oxidative Stress; Peptide Fragments; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Spectrin; Spinal Cord Injuries; Time Factors; Tyrosine; Up-Regulation

2007
Beneficial effects of FeTSPP, a peroxynitrite decomposition catalyst, in a mouse model of spinal cord injury.
    Free radical biology & medicine, 2007, Sep-01, Volume: 43, Issue:5

    Topics: Animals; Catalysis; Disease Models, Animal; DNA; I-kappa B Proteins; Interleukin-1beta; Interleukin-2; Lipid Peroxidation; Male; Metalloporphyrins; Mice; Mitochondria; Neutrophil Infiltration; NF-kappa B; Peroxidase; Peroxynitrous Acid; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Transport; Proto-Oncogene Proteins c-bcl-2; RNA; Spinal Cord Injuries; T-Lymphocytes; Tumor Necrosis Factor-alpha; Tyrosine

2007