Page last updated: 2024-09-03

peroxynitrous acid and Amyotrophic Lateral Sclerosis

peroxynitrous acid has been researched along with Amyotrophic Lateral Sclerosis in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (61.54)29.6817
2010's5 (38.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adamo, S; Bellezza, I; Costanzi, E; Grottelli, S; Mezzasoma, L; Minelli, A; Moresi, V; Morozzi, G; Peirce, MJ; Pigna, E; Scarpelli, P1
Barnes, S; Basso, M; Beal, MF; Beckman, JS; Calingasan, NY; Estévez, AG; Feldman, JL; Franco, MC; Grumet, M; Kiaei, M; Ma, TC; Mehl, R; Melero Fernández de Mera, RM; Refakis, CA; Rhoads, TW; Sparrow, NA; Stokes, AL; Ye, Y1
Miyazaki, Y; Nagase, M; Yamamoto, Y; Yoshino, H1
Basso, M; Beckman, JS; Bomben, VC; Estévez, AG; Franco, MC; Garner, MA; Ricart, KC; Roberts, BR; Sahawneh, J; Ye, Y1
Barnham, KJ; Bica, L; Crouch, PJ; Culvenor, JG; Donnelly, PS; Duce, J; Finkelstein, DI; Hickey, JL; Hung, LW; Lam, L; Li, QX; Lim, NK; Lim, S; Masters, CL; Morizzi, J; Powell, A; Sherratt, NA; Soon, CPW; Tan, JL; Turner, BJ; White, AR1
Cleveland, DW; deLapeyrière, O; Estévez, AG; Haase, G; Henderson, CE; Nishimune, H; Pettmann, B; Raoul, C1
Cheema, SS; Lopes, EC; Turner, BJ1
Barbeito, L; Beckman, JS; Cassina, P; Castellanos, R; Estévez, AG; Pehar, M; Vargas, MR; Viera, L1
Appel, SH; Beers, DR; He, Y; Henkel, JS; Le, W; Simpson, EP; Xiao, Q; Xie, W; Yen, AA; Zhao, W1
Chen, K; Liu, Z; Martin, LJ1
Bassi, MT; Clementi, E; De Palma, C; Falcone, S; Panzeri, C; Radice, S1
Barbeito, L; Beckman, JS; Cassina, P; Estévez, AG; Martinez-Palma, L; Pehar, M; Peluffo, H; Ressia, A1
Andreassen, OA; Beal, MF; Dedeoglu, A; Speer, O; Wallimann, T; Wendt, S1

Trials

1 trial(s) available for peroxynitrous acid and Amyotrophic Lateral Sclerosis

ArticleYear
Increased oxidative stress in patients with amyotrophic lateral sclerosis and the effect of edaravone administration.
    Redox report : communications in free radical research, 2016, Volume: 21, Issue:3

    Topics: Aged; Amyotrophic Lateral Sclerosis; Antipyrine; Biomarkers; Edaravone; Fatty Acids, Nonesterified; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Ubiquinone; Uric Acid

2016

Other Studies

12 other study(ies) available for peroxynitrous acid and Amyotrophic Lateral Sclerosis

ArticleYear
Peroxynitrite Activates the NLRP3 Inflammasome Cascade in SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis.
    Molecular neurobiology, 2018, Volume: 55, Issue:3

    Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Line, Transformed; Disease Models, Animal; Female; Mice; Mice, Inbred C57BL; Mice, Transgenic; NLR Family, Pyrin Domain-Containing 3 Protein; Peroxynitrous Acid; Superoxide Dismutase-1

2018
Nitration of Hsp90 induces cell death.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Mar-19, Volume: 110, Issue:12

    Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Death; Disease Models, Animal; fas Receptor; HSP90 Heat-Shock Proteins; Humans; Motor Neurons; Peroxynitrous Acid; Protein Processing, Post-Translational; Rats; Spinal Cord Injuries; Tyrosine

2013
Cu,Zn-superoxide dismutase increases toxicity of mutant and zinc-deficient superoxide dismutase by enhancing protein stability.
    The Journal of biological chemistry, 2010, 10-29, Volume: 285, Issue:44

    Topics: Amyotrophic Lateral Sclerosis; Animals; Animals, Genetically Modified; Apoptosis; Chelating Agents; Copper; Kinetics; Motor Neurons; Mutation; Neurons; Nitric Oxide; Peroxynitrous Acid; Proteins; Rats; Superoxide Dismutase

2010
Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII(atsm)) protects against peroxynitrite-induced nitrosative damage and prolongs survival in amyotrophic lateral sclerosis mouse model.
    The Journal of biological chemistry, 2011, Dec-23, Volume: 286, Issue:51

    Topics: Amyotrophic Lateral Sclerosis; Animals; Antioxidants; Astrocytes; Coordination Complexes; Copper; Disease Models, Animal; DNA-Binding Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Neurodegenerative Diseases; Neurons; Organometallic Compounds; Oxidative Stress; Oxygen; Peroxynitrous Acid; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Thiosemicarbazones; Transgenes

2011
Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations.
    Neuron, 2002, Sep-12, Volume: 35, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Amyotrophic Lateral Sclerosis; Animals; Carrier Proteins; Caspase 8; Caspase 9; Caspases; Cell Death; Cells, Cultured; Central Nervous System; Co-Repressor Proteins; fas Receptor; Fas-Associated Death Domain Protein; Female; Fetus; Genetic Linkage; Intracellular Signaling Peptides and Proteins; Male; MAP Kinase Kinase Kinase 5; MAP Kinase Kinase Kinases; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinases; Molecular Chaperones; Motor Neurons; Mutation; Nitric Oxide; Nitric Oxide Synthase; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Peroxynitrous Acid; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides; Up-Regulation

2002
Inducible superoxide dismutase 1 aggregation in transgenic amyotrophic lateral sclerosis mouse fibroblasts.
    Journal of cellular biochemistry, 2004, Apr-01, Volume: 91, Issue:5

    Topics: Acetylcysteine; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Blotting, Western; Cell Survival; Chelating Agents; Chlorides; Copper; Detergents; Disease Models, Animal; Ditiocarb; Fibroblasts; Humans; Immunohistochemistry; Mice; Mice, Transgenic; Minocycline; Mutation; Oxidative Stress; Paraquat; Peroxynitrous Acid; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Solubility; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Zinc Compounds

2004
Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis.
    Journal of neurochemistry, 2004, Volume: 89, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Animals; Antibodies; Apoptosis; Astrocytes; Cell Extracts; Cells, Cultured; Culture Media, Conditioned; Disease Models, Animal; Humans; Mice; Mice, Transgenic; Motor Neurons; Nerve Growth Factor; Nitric Oxide; Peroxynitrous Acid; Rats; Receptor, Nerve Growth Factor; Receptors, Nerve Growth Factor; Spinal Cord; Superoxide Dismutase

2004
Activated microglia initiate motor neuron injury by a nitric oxide and glutamate-mediated mechanism.
    Journal of neuropathology and experimental neurology, 2004, Volume: 63, Issue:9

    Topics: Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Catalase; Cell Communication; Cell Death; Cells, Cultured; Coculture Techniques; Free Radicals; Glutamic Acid; Glutathione; Microglia; Motor Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spinal Cord

2004
Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Jul-06, Volume: 25, Issue:27

    Topics: Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Anterior Horn Cells; Antioxidants; Apoptosis; Caspase 8; Caspases; Chromans; Disease Models, Animal; DNA Damage; DNA Glycosylases; DNA Repair; Enzyme Induction; Fas Ligand Protein; fas Receptor; Humans; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; NADPH Dehydrogenase; Necrosis; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxynitrous Acid; Point Mutation; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Sciatic Nerve; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides; Tumor Necrosis Factors; Tumor Suppressor Protein p53

2005
Endothelial nitric oxide synthase overexpression by neuronal cells in neurodegeneration: a link between inflammation and neuroprotection.
    Journal of neurochemistry, 2008, Volume: 106, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Cell Death; Cell Line, Tumor; Cell Survival; Cytoprotection; Encephalitis; Guanine Nucleotide Exchange Factors; Humans; Nerve Degeneration; Neurodegenerative Diseases; Neurons; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxynitrous Acid; Proto-Oncogene Proteins c-akt; Receptors, Lysosphingolipid; Transfection; Tumor Necrosis Factor-alpha

2008
Peroxynitrite triggers a phenotypic transformation in spinal cord astrocytes that induces motor neuron apoptosis.
    Journal of neuroscience research, 2002, Jan-01, Volume: 67, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Apoptosis; Astrocytes; Cell Communication; Cell Size; Cell Survival; Cells, Cultured; Enzyme Inhibitors; Fluorescent Antibody Technique; Free Radical Scavengers; Gliosis; Lipopolysaccharides; Motor Neurons; Nitric Oxide; Nitric Oxide Synthase; Peroxynitrous Acid; Phenotype; Rats; Receptor, Nerve Growth Factor; Spinal Cord

2002
Reduced creatine kinase activity in transgenic amyotrophic lateral sclerosis mice.
    Free radical biology & medicine, 2002, May-01, Volume: 32, Issue:9

    Topics: Amyotrophic Lateral Sclerosis; Animals; Blotting, Western; Cerebral Cortex; Chromium; Creatine Kinase; Creatinine; Diet; Dietary Supplements; Disease Models, Animal; Down-Regulation; Female; Male; Mice; Mice, Transgenic; Mitochondria; Peroxynitrous Acid; Respiration; Spinal Cord; Succinic Acid; Superoxide Dismutase; Superoxide Dismutase-1

2002