perindopril has been researched along with Diabetic Glomerulosclerosis in 54 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (3.70) | 18.7374 |
| 1990's | 9 (16.67) | 18.2507 |
| 2000's | 32 (59.26) | 29.6817 |
| 2010's | 11 (20.37) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Annaratone, L; Barutta, F; Bellini, S; Bruno, G; Corbetta, B; di Marzo, V; Gambino, R; Gruden, G; Makriyannis, A; Mastrocola, R; Piscitelli, F; Vemuri, VK | 1 |
| Chalmers, J; Cooper, ME; Glasziou, P; Hamet, P; Harrap, S; Jun, M; Mancia, G; Marre, M; Neal, B; Ohkuma, T; Perkovic, V; Poulter, N; Rodgers, A; Williams, B; Woodward, M; Zoungas, S | 1 |
| Jakjovski, K; Labacevski, N; Petrusevska, G; Trojacanec, J; Trojacanec, P; Zafirov, D; Zdravkovski, P | 1 |
| Helal, F; Lane, ME | 1 |
| Başar, M; Ertürküner, SP; Seçkin, İ; Tunçdemir, M | 1 |
| Öztürk, M; Tunçdemir, M | 1 |
| Amann, K; Boor, P; Heidland, A; Lill, M; Sebeková, K | 1 |
| Gilbert, RE; Kelly, DJ; Langham, RG; Tiauw, V; Wiggins, KJ; Zhang, Y | 1 |
| Chalmers, J; Joshi, R; Kengne, AP; MacMahon, S | 1 |
| Cass, A; Chalmers, J; Cooper, M; de Galan, BE; Glasziou, P; Grobbee, DE; Hamet, P; Harrap, S; MacMahon, S; Mancia, G; Marre, M; Mogensen, CE; Neal, B; Ninomiya, T; Patel, A; Perkovic, V; Pillai, A; Poulter, N; Williams, B; Woodward, M | 1 |
| Cheng, XY; Ge, N; Li, SM; Li, YY; Lu, JD; Shao, MM; Sun, HL; Sun, L | 1 |
| de la Sierra, A; Ruilope, LM; Waeber, B | 1 |
| Cass, A; Chalmers, J; Cooper, M; Grobbee, DE; Heerspink, HJ; Mancia, G; Mogensen, CE; Neal, B; Ninomiya, T; Perkovic, V; Woodward, M; Zoungas, S | 1 |
| Koya, D | 1 |
| Hamet, P | 1 |
| Chan, JS; Chenier, I; Filep, JG; Godin, N; Ingelfinger, JR; Liu, F; Lo, CS; Maachi, H; Shi, Y; Zhang, SL | 1 |
| Nedogoda, SV | 1 |
| Bicket, DP | 1 |
| Cordonnier, DJ; Cox, AJ; Gilbert, RE; Holthöfer, H; Kelly, DJ; Langham, RG; Pinel, N; Thomson, NM; Zaoui, P | 1 |
| Allen, TJ; Burns, WC; Burrell, LM; Cao, Z; Cooper, ME; Davis, BJ; Johnston, CI; Kubota, E | 1 |
| Allen, TJ; Burns, WC; Cooper, ME; Davis, BJ; Forbes, JM; Jerums, G; Kawachi, H; Thomas, MC | 1 |
| Hasegawa, K; Kuji, T; Ogawa, N; Shimura, G; Tochikubo, O; Umemura, S; Yasuda, G | 1 |
| Gilbert, RE; Kelly, DJ; Koji, T; Maguire, J; Stein-Oakley, A; Thomson, N; Wassef, L; Wilkinson-Berka, JL; Zhang, Y | 1 |
| Biswas, SK; de Faria, JB; de Faria, JM | 1 |
| Allen, TJ; Campbell, DJ; Cooper, ME; Gilbert, RE; Hammond, JJ; Jerums, G; O'Brien, RC; Raffaele, J; Tsalamandris, C | 1 |
| Boasquevisque, EM; de Lourdes Rodrigues, M; Francischetti, EA; Genelhu, V; Ismerim, VL; Matos, JP | 1 |
| Hu, G; Li, Y; Liao, Z; Yao, B; Zhang, Y | 1 |
| Altuntaş, Y; Aydin, L; Basturk, T; Eren, N; Kurklu, A; Unsal, A | 1 |
| Ruilope, LM; Segura, J | 1 |
| Cordonnier, DJ; Gilbert, RE; Gow, RM; Kelly, DJ; Langham, RG; Pinel, N; Zaoui, P; Zhang, Y | 1 |
| Brezniceanu, ML; Chan, JS; Chénier, I; Filep, JG; Ingelfinger, JR; Liu, F; Sachetelli, S; Wei, CC; Zhang, SL | 1 |
| Krzesinski, JM; Scheen, AJ | 1 |
| Cooper, ME; Doyle, AE; Jerums, G; O'Brien, RC | 1 |
| Charlesworth, JA; Duggan, KA; Hodge, G; Makarious, MM | 2 |
| Chen, J; He, R; Xia, H | 1 |
| Casiraghi, F; Gambara, V; Mosconi, L; Remuzzi, A; Remuzzi, G; Ruggenenti, P; Sangalli, F | 1 |
| Barro, C; Bilous, RW; Cordonnier, DJ; Halimi, S; Hurault de Ligny, B; Maynard, M; Pinel, N; Reznic, Y; Simon, D; Zaoui, P | 1 |
| Cheng, H; Fu, Z; Yan, L; Yan, T; Yang, R; Zhong, G | 1 |
| Baker, PR; Hoy, WE; Kelly, AM; Wang, Z | 1 |
| Glasser, SP | 1 |
| Gregersen, G; Kvetny, J; Pedersen, RS | 1 |
| Allen, TJ; Campbell, DJ; Cooper, ME; Gilbert, RE; Hammond, JJ; Jerums, G; Raffaele, J; Tsalamandris, C | 1 |
| Cooper, ME; Gibbs, NJ; Kelly, DJ; Skinner, SL; Wilkinson-Berka, JL | 1 |
| Bilous, RW; Cordonnier, DJ; Pinel, N; White, KE | 1 |
| Cooper, ME; Cox, AJ; Gilbert, RE; Kelly, DJ; Tolcos, M; Wilkinson-Berka, JL | 1 |
| Beyer, J; Bockisch, A; Frank, M; Kopf, D; Lehnert, H; Schmitz, H | 1 |
| Cooper, ME; Kelly, DJ; Mifsud, SA; Skinner, SL; Wilkinson-Berka, JL | 1 |
| Cox, AJ; Gilbert, RE; Kelly, DJ; Ricardo, SD; Wilkinson-Berka, JL | 1 |
| Aaltonen, P; Cox, AJ; Gilbert, RE; Holthöfer, H; Jerums, G; Kelly, DJ; Langham, R; Panagiotopoulos, S; Rumble, JR | 1 |
| Cooper, ME; Gin, T; Lim-Joon, T; Rumble, JR | 1 |
| Borgies, P; Brichard, SM; Colin, I; Hermans, MP; Ketelslegers, JM; Lambert, AE | 1 |
| Brichard, S; Ketelslegers, JM; Lambert, AE | 2 |
6 review(s) available for perindopril and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Transdermal delivery of Angiotensin Converting Enzyme inhibitors.
Topics: Administration, Cutaneous; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardiovascular Diseases; Diabetic Nephropathies; Enalapril; Heart Failure; Humans; Hypertension; Indoles; Lisinopril; Perindopril; Skin | 2014 |
The ADVANCE trial: clarifying the role of perindopril/indapamide fixed-dose combination in the reduction of cardiovascular and renal events in patients with diabetes mellitus.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Drug Combinations; Humans; Indapamide; Perindopril; Randomized Controlled Trials as Topic | 2009 |
What matters in ADVANCE and ADVANCE-ON.
Topics: Antihypertensive Agents; Biomarkers; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Drug Combinations; Glycated Hemoglobin; Humans; Hypertension; Hypoglycemic Agents; Incidence; Indapamide; Kidney Failure, Chronic; Multicenter Studies as Topic; Perindopril; Randomized Controlled Trials as Topic; Risk Factors | 2012 |
Using ACE inhibitors appropriately.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Captopril; Cardiovascular Diseases; Clinical Trials as Topic; Contraindications; Diabetic Nephropathies; Drug Costs; Enalapril; Fosinopril; Heart Failure; Humans; Hypertension; Indoles; Isoquinolines; Lisinopril; Meta-Analysis as Topic; Myocardial Infarction; Perindopril; Quinapril; Ramipril; Renin-Angiotensin System; Risk; Tetrahydroisoquinolines; United States | 2002 |
Renal protection in diabetic patients: benefits of a first-line combination of perindopril-indapamide (Preterax).
Topics: Albuminuria; Antihypertensive Agents; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Combinations; Humans; Hypertension; Indapamide; Perindopril | 2006 |
Angiotensin converting enzyme inhibitors: are they preferred first-line therapy?
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Comorbidity; Diabetic Nephropathies; Endothelium, Vascular; Humans; Hypertension; Perindopril; Randomized Controlled Trials as Topic; Renal Insufficiency; Treatment Outcome | 2000 |
20 trial(s) available for perindopril and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Acute Increases in Serum Creatinine After Starting Angiotensin-Converting Enzyme Inhibitor-Based Therapy and Effects of its Continuation on Major Clinical Outcomes in Type 2 Diabetes Mellitus.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cardiovascular Diseases; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Combinations; Drug Monitoring; Female; Humans; Indapamide; Male; Medication Therapy Management; Middle Aged; Perindopril; Risk Assessment; Treatment Outcome; Withholding Treatment | 2019 |
Blood pressure lowering with fixed combination perindopril-indapamide: key findings from ADVANCE.
Topics: Aged; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Combinations; Female; Follow-Up Studies; Humans; Hypertension, Renal; Indapamide; Male; Middle Aged; Perindopril; Placebos; Treatment Outcome | 2008 |
Lowering blood pressure reduces renal events in type 2 diabetes.
Topics: Age of Onset; Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Creatinine; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diastole; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Humans; Hypertension; Indapamide; Male; Perindopril; Systole | 2009 |
Effects of a fixed combination of perindopril and indapamide in patients with type 2 diabetes and chronic kidney disease.
Topics: Antihypertensive Agents; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Female; Humans; Hypertension, Renovascular; Indapamide; Male; Middle Aged; Myocardial Infarction; Perindopril; Renal Insufficiency, Chronic; Stroke; Treatment Outcome | 2010 |
[Lowering blood pressure and glucose reduces renal events in type 2 diabetes; ADVANCE study].
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Diuretics; Humans; Indapamide; Perindopril | 2010 |
Proteinuria and the expression of the podocyte slit diaphragm protein, nephrin, in diabetic nephropathy: effects of angiotensin converting enzyme inhibition.
Topics: Angiotensin-Converting Enzyme Inhibitors; Biopsy; Blood Pressure; Creatinine; Diabetic Nephropathies; Gene Expression Regulation; Glycated Hemoglobin; Humans; In Situ Hybridization; Membrane Proteins; Perindopril; Placebos; Proteins; Proteinuria | 2002 |
Long-term renoprotection by perindopril or nifedipine in non-hypertensive patients with Type 2 diabetes and microalbuminuria.
Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Perindopril; Prospective Studies | 2004 |
Effects of dual blockade of the renin angiotensin system in hypertensive type 2 diabetic patients with nephropathy.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Biphenyl Compounds; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Female; Humans; Hypertension; Irbesartan; Male; Middle Aged; Perindopril; Renin; Renin-Angiotensin System; Tetrazoles; Treatment Outcome | 2005 |
[The effect of perindopril in treatment of early diabetic nephropathy with normal blood pressure and microalbuminuria].
Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diabetic Nephropathies; Female; Humans; Kidney; Male; Middle Aged; Perindopril; Treatment Outcome | 2001 |
Transforming growth factor-beta in human diabetic nephropathy: effects of ACE inhibition.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Diabetes Mellitus, Type 2; Diabetic Nephropathies; DNA Primers; Female; Gene Expression Regulation; Humans; Kidney; Male; Middle Aged; Perindopril; Phosphorylation; Polymerase Chain Reaction; RNA; Smad2 Protein; Transforming Growth Factor beta | 2006 |
[Clinical trial of the month. ADVANCE: improved survival and better vascular and renal outcomes with a fixed combination of perindopril and indapamide in patients with type 2 diabetes].
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diuretics; Double-Blind Method; Drug Combinations; Female; Follow-Up Studies; Humans; Indapamide; Male; Middle Aged; Perindopril; Placebos; Prospective Studies; Survival Rate; Treatment Outcome | 2007 |
[Protective effect of angiotensin coverting enzyme inhibitor on renal function in normotensive non-insulin dependent diabetes mellitus patients with early diabetic nephropathy and microalbuminuria].
Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glomerular Filtration Rate; Humans; Indoles; Kidney; Middle Aged; Perindopril; Renal Plasma Flow | 1996 |
Glomerular size-selective dysfunction in NIDDM is not ameliorated by ACE inhibition or by calcium channel blockade.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Case-Control Studies; Cross-Over Studies; Dextrans; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Indoles; Kidney Glomerulus; Male; Middle Aged; Nitrendipine; Particle Size; Perindopril; Renal Circulation | 1999 |
Expansion of cortical interstitium is limited by converting enzyme inhibition in type 2 diabetic patients with glomerulosclerosis. The Diabiopsies Group.
Topics: Adult; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Biopsy, Needle; Confidence Intervals; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Female; Humans; Immunohistochemistry; Indoles; Kidney Cortex; Kidney Function Tests; Male; Middle Aged; Perindopril; Prognosis; Prospective Studies; Treatment Outcome | 1999 |
Reducing premature death and renal failure in Australian aboriginals. A community-based cardiovascular and renal protective program.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cause of Death; Death, Sudden, Cardiac; Diabetic Nephropathies; Diuretics; Female; Humans; Kidney Failure, Chronic; Longitudinal Studies; Male; Middle Aged; Native Hawaiian or Other Pacific Islander; Northern Territory; Perindopril; Survival Rate | 2000 |
Randomized placebo-controlled trial of perindopril in normotensive, normoalbuminuric patients with type 1 diabetes mellitus.
Topics: Adult; Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Creatinine; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Double-Blind Method; Female; Genotype; Glomerular Filtration Rate; Humans; Male; Middle Aged; Peptidyl-Dipeptidase A; Perindopril; Prospective Studies | 2001 |
Long-term comparison between perindopril and nifedipine in normotensive patients with type 1 diabetes and microalbuminuria.
Topics: Adolescent; Adult; Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nifedipine; Perindopril; Prospective Studies; Statistics as Topic | 2001 |
Does ACE inhibition slow progression of glomerulopathy in patients with Type 2 diabetes mellitus?
Topics: Angiotensin-Converting Enzyme Inhibitors; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Hypertension; Kidney Glomerulus; Microscopy, Electron; Middle Aged; Perindopril; Placebos; Proteinuria | 2001 |
A double-blind trial of perindopril and nitrendipine in incipient diabetic nephropathy.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Creatinine; Diabetic Nephropathies; Double-Blind Method; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Nitrendipine; Perindopril; Proteinuria; Technetium Tc 99m Pentetate | 2001 |
Renal function, glycemic control and perindopril in diabetic patients.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Blood Pressure; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Humans; Hypertension; Indoles; Kidney; Middle Aged; Perindopril | 1989 |
28 other study(ies) available for perindopril and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Reversal of albuminuria by combined AM6545 and perindopril therapy in experimental diabetic nephropathy.
Topics: Albuminuria; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Male; Mice; Mice, Inbred C57BL; Morpholines; Perindopril; Pyrazoles; Receptor, Cannabinoid, CB1 | 2018 |
Perindopril treatment in streptozotocin induced diabetic nephropaty.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Blood Urea Nitrogen; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Glomerulonephritis; Hypertrophy; Kidney; Male; Perindopril; Rats, Wistar; Streptozocin; Time Factors | 2013 |
The comparative effects of perindopril and catechin on mesangial matrix and podocytes in the streptozotocin induced diabetic rats.
Topics: Albuminuria; Animals; Blood Glucose; Catechin; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glomerular Mesangium; Male; Microscopy, Electron; Perindopril; Podocytes; Rats; Rats, Wistar; Streptozocin; Transforming Growth Factor beta1 | 2014 |
Regulation of the Ku70 and apoptosis-related proteins in experimental diabetic nephropathy.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Biphenyl Compounds; Blood Glucose; Caspase 3; Cytochromes c; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Irbesartan; Kidney; Kidney Glomerulus; Kidney Tubules; Ku Autoantigen; Male; Perindopril; Rats; Rats, Wistar; Tetrazoles | 2016 |
Functional and partial morphological regression of established renal injury in the obese zucker rat by blockade of the renin-angiotensin system.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Diabetic Nephropathies; Kidney Function Tests; Kidney Glomerulus; Male; Organ Size; Oxidative Stress; Perindopril; Proteinuria; Random Allocation; Rats; Rats, Zucker; Tetrazoles | 2009 |
Perindopril attenuates tubular hypoxia and inflammation in an experimental model of diabetic nephropathy in transgenic Ren-2 rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Fibrosis; Hypoxia; Immunohistochemistry; Inflammation; Kidney Tubules; Macrophages; Nitroimidazoles; Osteopontin; Perindopril; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Renin-Angiotensin System; Time Factors | 2008 |
ACE-inhibitor suppresses the apoptosis induced by endoplasmic reticulum stress in renal tubular in experimental diabetic rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Evaluation, Preclinical; eIF-2 Kinase; Endoplasmic Reticulum; Heat-Shock Proteins; Kidney Tubules; Male; Molecular Chaperones; Perindopril; Rats; Rats, Sprague-Dawley; Streptozocin; Stress, Physiological | 2009 |
Dual RAS blockade normalizes angiotensin-converting enzyme-2 expression and prevents hypertension and tubular apoptosis in Akita angiotensinogen-transgenic mice.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Gene Expression; Hypertension; Kidney; Kidney Tubules, Proximal; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nephrosclerosis; Peptidyl-Dipeptidase A; Perindopril; Rats; Renin-Angiotensin System; Transgenes | 2012 |
[Nephroprotection diabetes mellitus type 2: lessons from the ADVANCE trial].
Topics: Antihypertensive Agents; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Humans; Hypertension; Indapamide; Perindopril; Randomized Controlled Trials as Topic | 2011 |
Renoprotective effects of vasopeptidase inhibition in an experimental model of diabetic nephropathy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Hypertension; Immunohistochemistry; Kidney; Male; Membrane Proteins; Peptidyl-Dipeptidase A; Perindopril; Proteins; Rats; Rats, Inbred SHR; Reference Values | 2003 |
Superior renoprotective effects of combination therapy with ACE and AGE inhibition in the diabetic spontaneously hypertensive rat.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Guanidines; Kidney; Kidney Glomerulus; Male; Perindopril; Rats; Rats, Inbred SHR | 2004 |
Perindopril effects on ambulatory blood pressure: relation to sympathetic nervous activity in subjects with diabetic nephropathy.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Diabetic Nephropathies; Electrocardiography; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Perindopril; Renin; Signal Processing, Computer-Assisted; Sympathetic Nervous System | 2004 |
Fas-induced apoptosis is a feature of progressive diabetic nephropathy in transgenic (mRen-2)27 rats: attenuation with renin-angiotensin blockade.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Fas Ligand Protein; fas Receptor; Female; Membrane Glycoproteins; Perindopril; Rats | 2004 |
Davis BJ, Forbes JM, Thomas MC et al. (2004) Superior renoprotective effects of combination therapy with ACE and AGE inhibition in the diabetic spontaneously hypertensive rat. Diabetologia 47:89-97.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Therapy, Combination; Guanidines; Nitric Oxide Synthase; Perindopril; Rats; Rats, Inbred SHR | 2004 |
Urinary N-acetyl B glucosaminidase as an earlier marker of diabetic nephropathy and influence of low-dose perindopril/indapamide combination.
Topics: Acetylglucosaminidase; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biomarkers; Diabetic Nephropathies; Female; Humans; Indapamide; Male; Middle Aged; Perindopril | 2006 |
Overexpression of angiotensinogen increases tubular apoptosis in diabetes.
Topics: Albuminuria; Angiotensinogen; Animals; Antihypertensive Agents; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Blood Glucose; Cell Line, Transformed; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Hydralazine; Hypertension, Renal; Hypoglycemic Agents; Insulin; Kidney Tubules, Proximal; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Perindopril; Rats; Renin-Angiotensin System | 2008 |
The effects of perindopril and triple therapy in a normotensive model of diabetic nephropathy.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Therapy, Combination; Glomerular Filtration Rate; Glomerular Mesangium; Hydralazine; Hydrochlorothiazide; Indoles; Kidney Glomerulus; Male; Perindopril; Rats; Rats, Sprague-Dawley; Reserpine | 1993 |
Acute but not chronic angiotensin-converting enzyme inhibition induces enzyme synthesis in the glomerulus of the spontaneously hypertensive rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Administration Schedule; Enzyme Induction; Female; Indoles; Kidney Glomerulus; Peptidyl-Dipeptidase A; Perindopril; Rats; Rats, Inbred SHR | 1997 |
Renoprotective differences between perindopril and enalapril in the diabetic hypertensive rat do not reflect glomerular angiotensin-converting enzyme activity.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enalapril; Indoles; Kidney Glomerulus; Peptidyl-Dipeptidase A; Perindopril; Proteins; Random Allocation; Rats; Rats, Inbred SHR | 1998 |
Protective effect of the angiotensin-converting enzyme inhibitor perindopril on diabetic glomerulopathy in streptozotocin-induced diabetic rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Indoles; Male; Perindopril; Random Allocation; Rats; Rats, Wistar | 1998 |
Renoprotective and anti-hypertensive effects of combined valsartan and perindopril in progressive diabetic nephropathy in the transgenic (mRen-2)27 rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Drug Therapy, Combination; Female; Heterozygote; Kidney; Perindopril; Rats; Renin; Tetrazoles; Valine; Valsartan | 2001 |
Attenuation of tubular apoptosis by blockade of the renin-angiotensin system in diabetic Ren-2 rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Apoptosis; Atrophy; Autoradiography; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Epidermal Growth Factor; Female; Fibrosis; Gene Expression; In Situ Hybridization; In Situ Nick-End Labeling; Kidney Tubules; Nephritis, Interstitial; Perindopril; Rats; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta; Valine; Valsartan | 2002 |
Effects of low-dose and early versus late perindopril treatment on the progression of severe diabetic nephropathy in (mREN-2)27 rats.
Topics: Animals; Animals, Genetically Modified; Blood Pressure; Body Weight; Collagen; Diabetic Nephropathies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glomerulosclerosis, Focal Segmental; Kidney; Kidney Medulla; Organ Size; Perindopril; Rats; Renin; Systole | 2002 |
Progression of tubulointerstitial injury by osteopontin-induced macrophage recruitment in advanced diabetic nephropathy of transgenic (mRen-2)27 rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Female; Humans; Kidney; Kidney Tubules; Macrophages; Osteopontin; Perindopril; Rats; Renin; Sialoglycoproteins; Transcription, Genetic | 2002 |
Expression of the slit-diaphragm protein, nephrin, in experimental diabetic nephropathy: differing effects of anti-proteinuric therapies.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Base Sequence; Diabetes Mellitus, Experimental; Diabetic Nephropathies; DNA Primers; Guanidines; In Situ Hybridization; Male; Membrane Proteins; Mutation; Perindopril; Proteins; Proteinuria; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |
Diabetic renal microvascular disease: the role of hypertension and ACE inhibitors.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diabetic Nephropathies; Dihydropyridines; Hypertension, Renovascular; Indoles; Kidney Glomerulus; Male; Perindopril; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1992 |
Long-term reduction of microalbuminuria after 3 years of angiotensin-converting enzyme inhibition by perindopril in hypertensive insulin-treated diabetic patients.
Topics: Albuminuria; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Creatinine; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Female; Humans; Hypertension; Indoles; Insulin; Male; Middle Aged; Perindopril | 1992 |
Renal function, glycaemic control and perindopril in diabetic patients.
Topics: Albuminuria; Antihypertensive Agents; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Nephropathies; Humans; Hypertension; Indoles; Kidney; Middle Aged; Perindopril | 1989 |