Page last updated: 2024-08-21

perillyl alcohol and Neoplasms

perillyl alcohol has been researched along with Neoplasms in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (21.43)18.2507
2000's6 (42.86)29.6817
2010's4 (28.57)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Arellano, ML; Boggon, TJ; Brat, DJ; Chen, GZ; Chen, J; Chen, PR; DeBerardinis, RJ; Elf, S; Fan, J; Gu, TL; He, C; Hitosugi, T; Hurwitz, SJ; Ji, Q; Jiang, L; Kang, HB; Kang, S; Khoury, HJ; Khuri, FR; Lee, BH; Lei, Q; Li, Y; Lin, R; Lonial, S; Mao, H; Mitsche, M; Seo, JH; Shan, C; Sudderth, J; Tucker, M; Wang, D; Wu, S; Xie, J; Ye, K; Zhang, L; Zhang, S; Zhou, L1
da Silva, CEH; de Andrade, SF; Gosmann, G1
Chen, TC; Hofman, FM; Myint, PT; Nouri Nigjeh, E; Schönthal, AH; Wang, W; Yu, J; Zandi, E1
Adu-Frimpong, M; Mukhtar, YM; Xu, X; Yu, J1
Albuquerque Júnior, RL; Amaral, RG; Andrade, LN; Carvalho, AA; da Silva, TK; de Sousa, DP; do Nascimento, LG; Dória, GA; Fonseca, CS; Thomazzi, SM1
Azzoli, CG; Kris, MG; Krug, LM; Miller, VA; Ng, KK; Riedel, ER; Spriggs, DR; Tong, WP1
Alberti, D; Arzoomanin, R; Bailey, H; Binger, K; Black, S; Dubey, S; Ellingen, S; Feierabend, C; Gould, M; Marnocha, R; Morgan-Meadows, S; Pomplun, M; Tutsch, K; Volkman, J; Wilding, G1
Alberti, D; Arzoomanian, RZ; Bailey, HH; Feierabend, C; Hohl, RJ; Holstein, SA; Lewis, KA; Marnocha, R; Simon, K; Stewart, J; Tutsch, KD; Wilding, G1
Buechler, RD; Hentosh, P; Peffley, DM; Sharma, C1
Hohl, RJ; Lewis, KA1
Alberti, D; Arzoomanian, RZ; Bailey, HH; Feierabend, C; Gould, MN; Pomplun, M; Ripple, GH; Stewart, JA; Tutsch, KD; Wilding, G1
Belanger, JT1
Alberti, D; Arzoomanian, RZ; Bailey, HH; Binger, K; Feierabend, C; Gould, MN; Marnocha, R; Pomplun, M; Ripple, GH; Simon, K; Tutsch, KD; Wahamaki, A; Wilding, G1
Adams, A; Gallo, JM; Halberr, T; Hudes, GR; Langer, CJ; Litwin, S; McCauley, RA; Qian, M; Ranganathan, S; Szarka, CE; Weiner, LM; Yeslow, G1

Reviews

4 review(s) available for perillyl alcohol and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; Oxidative Stress; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Protein Serine-Threonine Kinases; Ribulosephosphates; Signal Transduction

2015
Limonene and Perillyl Alcohol Derivatives: Synthesis and Anticancer Activity.
    Mini reviews in medicinal chemistry, 2021, Volume: 21, Issue:14

    Topics: Antineoplastic Agents; Carbohydrates; Cell Survival; Humans; Limonene; Monoterpenes; Neoplasms; Structure-Activity Relationship; Thiosemicarbazones

2021
Biochemical significance of limonene and its metabolites: future prospects for designing and developing highly potent anticancer drugs.
    Bioscience reports, 2018, 12-21, Volume: 38, Issue:6

    Topics: Cyclohexenes; Drug Design; Humans; Limonene; Methyl Ethers; Monoterpenes; Neoplasms

2018
Perillyl alcohol: applications in oncology.
    Alternative medicine review : a journal of clinical therapeutic, 1998, Volume: 3, Issue:6

    Topics: Animals; Antineoplastic Agents; Clinical Trials, Phase I as Topic; Humans; Monoterpenes; Neoplasms; Terpenes

1998

Trials

6 trial(s) available for perillyl alcohol and Neoplasms

ArticleYear
A phase I trial of perillyl alcohol in patients with advanced solid tumors.
    Cancer chemotherapy and pharmacology, 2003, Volume: 51, Issue:6

    Topics: Antineoplastic Agents; Female; Humans; Male; Middle Aged; Monoterpenes; Nausea; Neoplasms; Proto-Oncogene Mas; Surveys and Questionnaires; Vomiting

2003
Phase I trial of perillyl alcohol administered four times daily continuously.
    Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Area Under Curve; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Male; Middle Aged; Monoterpenes; Neoplasms

2003
A phase I trial of perillyl alcohol administered four times daily for 14 days out of 28 days.
    Cancer chemotherapy and pharmacology, 2004, Volume: 54, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Monoterpenes; Neoplasms

2004
Phase I clinical trial of perillyl alcohol administered daily.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Digestive System; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Monoterpenes; Neoplasms; Neutropenia; Terpenes

1998
Phase I clinical and pharmacokinetic study of perillyl alcohol administered four times a day.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:2

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Area Under Curve; Biotransformation; Drug Administration Schedule; Female; Half-Life; Humans; Male; Middle Aged; Monoterpenes; Neoplasms; Terpenes

2000
Phase I pharmacokinetic trial of perillyl alcohol (NSC 641066) in patients with refractory solid malignancies.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:8

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Phytogenic; Cyclohexenes; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Monoterpenes; Neoplasms; Proto-Oncogene Proteins p21(ras); Terpenes; Tumor Cells, Cultured

2000

Other Studies

4 other study(ies) available for perillyl alcohol and Neoplasms

ArticleYear
A perillyl alcohol-conjugated analog of 3-bromopyruvate without cellular uptake dependency on monocarboxylate transporter 1 and with activity in 3-BP-resistant tumor cells.
    Cancer letters, 2017, 08-01, Volume: 400

    Topics: Adenosine Triphosphate; Alkylation; Antineoplastic Agents; Antioxidants; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; HCT116 Cells; Humans; MCF-7 Cells; Monocarboxylic Acid Transporters; Monoterpenes; Necrosis; Neoplasms; Pyruvates; RNA Interference; Signal Transduction; Symporters; Transfection

2017
In Vivo Anti-Tumor Activity and Toxicological Evaluations of Perillaldehyde 8,9-Epoxide, a Derivative of Perillyl Alcohol.
    International journal of molecular sciences, 2016, Jan-04, Volume: 17, Issue:1

    Topics: Animals; Antineoplastic Agents; Female; Fluorouracil; Mice; Monoterpenes; Neoplasm Transplantation; Neoplasms

2016
Perillyl alcohol and genistein differentially regulate PKB/Akt and 4E-BP1 phosphorylation as well as eIF4E/eIF4G interactions in human tumor cells.
    Archives of biochemistry and biophysics, 2007, Sep-01, Volume: 465, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Cell Cycle Proteins; Cell Line, Tumor; Dose-Response Relationship, Drug; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4G; Gene Expression Regulation, Neoplastic; Genistein; Humans; Monoterpenes; Neoplasms; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction

2007
Modulation of RAS expression in human malignant cells by dietary supplements.
    Nutrition (Burbank, Los Angeles County, Calif.), 1997, Volume: 13, Issue:10

    Topics: Antineoplastic Agents; Cyclohexenes; Dietary Supplements; Fatty Acids, Omega-3; Garlic; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Limonene; Monoterpenes; Neoplasms; Plants, Medicinal; Tea; Terpenes

1997