perillyl alcohol has been researched along with Brain Neoplasms in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 3 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| Amorim, MR; D'Alincourt Salazar, M; da Fonseca, CO; Faria, GM; Pessoa, BL; Quirico-Santos, T; Soares, IDP | 1 |
| Beringer, PM; Chen, L; Chen, TC; Cho, HY; Fu, J; He, H; Marín-Ramos, NI; Neman, J; Schönthal, AH; Swenson, SD; Wang, W; Zeng, S | 1 |
| Andrews, S; Gould, MN; Haag, JD; Howard, SP; Nehra, G; Rettig, J; Thorne, RG | 1 |
| Da Fonseca, CO; Garcia, DG; Gomes, AC; Mello, AL; Quirico-Santos, T; Ribeiro, MG; Salazar, MD; Schönthal, AH | 1 |
| Chen, TC; da Fonseca, CO; Schönthal, AH | 2 |
| DA Fonseca, CO; DE Saldanha DA Gama Fischer, J; Landeiro, JA; Meirelles, OC; Quirico-Santos, T; Silva, JC; Teixeira, RM | 1 |
| Barath, M; Chen, TC; Cho, HY; Hofman, FM; Schönthal, AH; Sharma, N; Wang, W | 1 |
| Afshordel, S; Clasohm, J; Eckert, GP; Kern, B; Kögel, D; König, H; Priester, M; Weissenberger, J | 1 |
| Arnobio, A; Da Fonseca, CO; Futuro, D; Lins, IR; Quirico-Santos, T; Silva, JT; Simão, M | 1 |
| Caetano, RO; da Fonseca, CO; Futuro, D; Lins, IR; Quirico-Santos, T; Simão, M | 1 |
| da Fonseca, CO; da Silveira, Fd; de Amorim, LM; de Palmer Paixão, IC; Lopes, Bde A; Quirico-Santos, T | 1 |
| Chen, TC; Cho, HY; Goldkorn, A; Hofman, FM; Jhaveri, N; Lee, DJ; Leong, MN; Louie, SG; Petasis, NA; Schönthal, AH; Torres, S; Tseng, J; Wang, W; Xu, T | 1 |
| Clark, SS; da Costa Carvalho, Mda G; da Fonseca, CO; Gattass, CR; Landeiro, JA; Quirico-Santos, T | 1 |
| Caetano, R; Da Fonseca, CO; Futuro, D; Gattass, CR; Masini, M; Quirico-Santos, T | 1 |
| da Fonseca, CO; Fischer, J; Futuro, D; Gattass, CR; Nagel, J; Quirico-Santos, T; Schwartsmann, G | 1 |
5 review(s) available for perillyl alcohol and Brain Neoplasms
| Article | Year |
|---|---|
Perillyl alcohol, a pleiotropic natural compound suitable for brain tumor therapy, targets free radicals.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carcinogenesis; Endoplasmic Reticulum Stress; Free Radical Scavengers; Glioblastoma; Humans; Hypoxia; Lipid Peroxidation; Monoterpenes; Oxidative Stress; Reactive Oxygen Species; Tumor Microenvironment; Unfolded Protein Response | 2017 |
Intranasal Perillyl Alcohol for Glioma Therapy: Molecular Mechanisms and Clinical Development.
Topics: Administration, Intranasal; Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Glioma; Humans; Monoterpenes; Signal Transduction; Treatment Outcome | 2018 |
Perillyl Alcohol and Its Drug-Conjugated Derivatives as Potential Novel Methods of Treating Brain Metastases.
Topics: Administration, Intranasal; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Drug Carriers; Humans; Monoterpenes | 2016 |
Recent advances in the molecular genetics of malignant gliomas disclose targets for antitumor agent perillyl alcohol.
Topics: Antineoplastic Agents; Brain Neoplasms; Glioma; Humans; Molecular Biology; Monoterpenes | 2006 |
Anaplastic oligodendroglioma responding favorably to intranasal delivery of perillyl alcohol: a case report and literature review.
Topics: Administration, Inhalation; Administration, Intranasal; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Frontal Lobe; Humans; Karnofsky Performance Status; Magnetic Resonance Imaging; Middle Aged; Monoterpenes; Oligodendroglioma; Treatment Outcome | 2006 |
2 trial(s) available for perillyl alcohol and Brain Neoplasms
| Article | Year |
|---|---|
Intranasal perillyl alcohol therapy improves survival of patients with recurrent glioblastoma harboring mutant variant for MTHFR rs1801133 polymorphism.
Topics: Administration, Intranasal; Adolescent; Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasms; DNA Methylation; Female; Glioblastoma; Humans; Leukocytes; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Monoterpenes; Neoplasm Recurrence, Local; Polymorphism, Single Nucleotide; Young Adult | 2020 |
Preliminary results from a phase I/II study of perillyl alcohol intranasal administration in adults with recurrent malignant gliomas.
Topics: Administration, Intranasal; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Administration Schedule; Enzyme Inhibitors; Female; Glioma; Humans; Magnetic Resonance Imaging; Male; Monoterpenes; Neoplasm Recurrence, Local; Oncogene Protein p21(ras); Signal Transduction; Survival Rate; Temozolomide; Transforming Growth Factor beta; Treatment Outcome | 2008 |
9 other study(ies) available for perillyl alcohol and Brain Neoplasms
| Article | Year |
|---|---|
Enhanced brain delivery and therapeutic activity of trastuzumab after blood-brain barrier opening by NEO100 in mouse models of brain-metastatic breast cancer.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Neoplasms; Breast Neoplasms; Endothelial Cells; Female; Humans; Mice; Monoterpenes; Receptor, ErbB-2; Trastuzumab | 2021 |
Intranasal administration of the chemotherapeutic perillyl alcohol results in selective delivery to the cerebrospinal fluid in rats.
Topics: Administration, Intranasal; Animals; Blood-Brain Barrier; Brain; Brain Neoplasms; Chromatography, High Pressure Liquid; Disease Models, Animal; Humans; Monoterpenes; Nasal Mucosa; Rats; Trigeminal Nerve | 2021 |
Long-term outcome in patients with recurrent malignant glioma treated with Perillyl alcohol inhalation.
Topics: Administration, Inhalation; Adult; Antineoplastic Agents; Brain Neoplasms; Female; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Monoterpenes; Recurrence; Treatment Outcome | 2013 |
A novel temozolomide-perillyl alcohol conjugate exhibits superior activity against breast cancer cells in vitro and intracranial triple-negative tumor growth in vivo.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; Disease Models, Animal; DNA Modification Methylases; DNA Repair Enzymes; Drug Combinations; Drug Resistance, Neoplasm; Humans; Mice; Monoterpenes; Temozolomide; Triple Negative Breast Neoplasms; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2014 |
Lovastatin and perillyl alcohol inhibit glioma cell invasion, migration, and proliferation--impact of Ras-/Rho-prenylation.
Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cholesterol; Glioma; Humans; Lovastatin; Monoterpenes; Neoplasm Invasiveness; Prenylation; rac1 GTP-Binding Protein; ras Proteins; Terpenes | 2015 |
Correlation of tumor topography and peritumoral edema of recurrent malignant gliomas with therapeutic response to intranasal administration of perillyl alcohol.
Topics: Administration, Intranasal; Adult; Aged; Antineoplastic Agents; Brain Edema; Brain Neoplasms; Disease-Free Survival; Female; Glioma; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Monoterpenes; Neoplasm Recurrence, Local; Treatment Outcome | 2009 |
Efficacy of monoterpene perillyl alcohol upon survival rate of patients with recurrent glioblastoma.
Topics: Administration, Intranasal; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Drug Administration Schedule; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Middle Aged; Monoterpenes; Neoplasm Recurrence, Local; Patient Selection | 2011 |
Analysis of EGF+61A>G polymorphism and EGF serum levels in Brazilian glioma patients treated with perillyl alcohol-based therapy.
Topics: Administration, Intranasal; Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Brain Neoplasms; Brazil; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Epidermal Growth Factor; Female; Gene Frequency; Genotype; Glioma; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Monoterpenes; Polymorphism, Single Nucleotide; Prospective Studies; Survival Analysis; Treatment Outcome; Young Adult | 2012 |
Perillyl alcohol for the treatment of temozolomide-resistant gliomas.
Topics: Administration, Intranasal; Animals; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Cytokines; Dacarbazine; Drug Resistance, Neoplasm; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Glioma; Humans; Mice; Monoterpenes; Nelfinavir; Neoplasm Invasiveness; Neovascularization, Pathologic; Pyrazoles; Sulfonamides; Temozolomide; Xenograft Model Antitumor Assays | 2012 |