Page last updated: 2024-10-21

perillic acid and Neoplasms

perillic acid has been researched along with Neoplasms in 3 studies

perillic acid: d-limonene metabolite; structure given in first source

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Perillyl alcohol (POH) is a monoterpene with anticarcinogenic and antitumor activity in murine tumor models."2.69Phase I pharmacokinetic trial of perillyl alcohol (NSC 641066) in patients with refractory solid malignancies. ( Adams, A; Gallo, JM; Halberr, T; Hudes, GR; Langer, CJ; Litwin, S; McCauley, RA; Qian, M; Ranganathan, S; Szarka, CE; Weiner, LM; Yeslow, G, 2000)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Mukhtar, YM1
Adu-Frimpong, M1
Xu, X1
Yu, J1
Hudes, GR1
Szarka, CE1
Adams, A1
Ranganathan, S1
McCauley, RA1
Weiner, LM1
Langer, CJ1
Litwin, S1
Yeslow, G1
Halberr, T1
Qian, M1
Gallo, JM1

Reviews

2 reviews available for perillic acid and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015
Biochemical significance of limonene and its metabolites: future prospects for designing and developing highly potent anticancer drugs.
    Bioscience reports, 2018, 12-21, Volume: 38, Issue:6

    Topics: Cyclohexenes; Drug Design; Humans; Limonene; Methyl Ethers; Monoterpenes; Neoplasms

2018

Trials

1 trial available for perillic acid and Neoplasms

ArticleYear
Phase I pharmacokinetic trial of perillyl alcohol (NSC 641066) in patients with refractory solid malignancies.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:8

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Phytogenic; Cyclohexenes; Dose-Response Re

2000