Page last updated: 2024-09-04

perifosine and Thyroid Neoplasms

perifosine has been researched along with Thyroid Neoplasms in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hou, P; Liu, D; Liu, Z; Wu, G; Xing, M1
Bojdani, E; Hou, P; Xing, M1
Liu, D; Liu, R; Xing, M1
Howe, JR; Komorowski, RA; Lal, G; O'Malley, Y; Shilyansky, J; Sugg, SL; Weigel, RJ1

Other Studies

4 other study(ies) available for perifosine and Thyroid Neoplasms

ArticleYear
Genetic alterations in the phosphoinositide 3-kinase/Akt signaling pathway confer sensitivity of thyroid cancer cells to therapeutic targeting of Akt and mammalian target of rapamycin.
    Cancer research, 2009, Sep-15, Volume: 69, Issue:18

    Topics: Animals; Cell Growth Processes; Cell Line, Tumor; Class I Phosphatidylinositol 3-Kinases; Humans; Mice; Mice, Nude; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylcholine; Protein Kinases; RNA, Small Interfering; Signal Transduction; Sirolimus; Thyroid Neoplasms; TOR Serine-Threonine Kinases; Transfection; Xenograft Model Antitumor Assays

2009
Induction of thyroid gene expression and radioiodine uptake in thyroid cancer cells by targeting major signaling pathways.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:2

    Topics: Cell Line, Tumor; Gene Expression Regulation; Humans; Hydroxamic Acids; Intracellular Signaling Peptides and Proteins; Iodine Radioisotopes; MAP Kinase Signaling System; Phosphatidylinositol 3-Kinases; Phosphorylcholine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Symporters; Thyroid Gland; Thyroid Neoplasms; Thyrotropin; TOR Serine-Threonine Kinases; Vorinostat

2010
The Akt inhibitor MK2206 synergizes, but perifosine antagonizes, the BRAF(V600E) inhibitor PLX4032 and the MEK1/2 inhibitor AZD6244 in the inhibition of thyroid cancer cells.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carcinoma; Cell Proliferation; Down-Regulation; Drug Antagonism; Drug Evaluation, Preclinical; Drug Synergism; Glutamic Acid; Heterocyclic Compounds, 3-Ring; Humans; Indoles; Mutant Proteins; Oncogene Protein v-akt; Phosphorylcholine; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Sulfonamides; Thyroid Neoplasms; Tumor Cells, Cultured; Valine; Vemurafenib

2012
Invasion in follicular thyroid cancer cell lines is mediated by EphA2 and pAkt.
    Surgery, 2012, Volume: 152, Issue:6

    Topics: Adenocarcinoma, Follicular; Cell Line, Tumor; Humans; Immunoblotting; Neoplasm Invasiveness; Phosphorylation; Phosphorylcholine; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Receptor, EphA2; RNA, Small Interfering; Thyroid Neoplasms; Tumor Cells, Cultured

2012