perifosine has been researched along with Thyroid Neoplasms in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hou, P; Liu, D; Liu, Z; Wu, G; Xing, M | 1 |
| Bojdani, E; Hou, P; Xing, M | 1 |
| Liu, D; Liu, R; Xing, M | 1 |
| Howe, JR; Komorowski, RA; Lal, G; O'Malley, Y; Shilyansky, J; Sugg, SL; Weigel, RJ | 1 |
4 other study(ies) available for perifosine and Thyroid Neoplasms
| Article | Year |
|---|---|
Genetic alterations in the phosphoinositide 3-kinase/Akt signaling pathway confer sensitivity of thyroid cancer cells to therapeutic targeting of Akt and mammalian target of rapamycin.
Topics: Animals; Cell Growth Processes; Cell Line, Tumor; Class I Phosphatidylinositol 3-Kinases; Humans; Mice; Mice, Nude; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylcholine; Protein Kinases; RNA, Small Interfering; Signal Transduction; Sirolimus; Thyroid Neoplasms; TOR Serine-Threonine Kinases; Transfection; Xenograft Model Antitumor Assays | 2009 |
Induction of thyroid gene expression and radioiodine uptake in thyroid cancer cells by targeting major signaling pathways.
Topics: Cell Line, Tumor; Gene Expression Regulation; Humans; Hydroxamic Acids; Intracellular Signaling Peptides and Proteins; Iodine Radioisotopes; MAP Kinase Signaling System; Phosphatidylinositol 3-Kinases; Phosphorylcholine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Symporters; Thyroid Gland; Thyroid Neoplasms; Thyrotropin; TOR Serine-Threonine Kinases; Vorinostat | 2010 |
The Akt inhibitor MK2206 synergizes, but perifosine antagonizes, the BRAF(V600E) inhibitor PLX4032 and the MEK1/2 inhibitor AZD6244 in the inhibition of thyroid cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carcinoma; Cell Proliferation; Down-Regulation; Drug Antagonism; Drug Evaluation, Preclinical; Drug Synergism; Glutamic Acid; Heterocyclic Compounds, 3-Ring; Humans; Indoles; Mutant Proteins; Oncogene Protein v-akt; Phosphorylcholine; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Sulfonamides; Thyroid Neoplasms; Tumor Cells, Cultured; Valine; Vemurafenib | 2012 |
Invasion in follicular thyroid cancer cell lines is mediated by EphA2 and pAkt.
Topics: Adenocarcinoma, Follicular; Cell Line, Tumor; Humans; Immunoblotting; Neoplasm Invasiveness; Phosphorylation; Phosphorylcholine; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Receptor, EphA2; RNA, Small Interfering; Thyroid Neoplasms; Tumor Cells, Cultured | 2012 |