perifosine has been researched along with Leukemia, Myeloid, Acute in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Aiche, S; Bassermann, F; Becker, W; Canevari, G; Casale, E; Depaolini, SR; Ehrlich, HC; Felder, ER; Feuchtinger, A; Garz, AK; Gohlke, BO; Götze, K; Greif, PA; Hahne, H; Heinzlmeir, S; Helm, D; Huenges, J; Jeremias, I; Kayser, G; Klaeger, S; Koch, H; Koenig, PA; Kramer, K; Kuster, B; Médard, G; Meng, C; Petzoldt, S; Polzer, H; Preissner, R; Qiao, H; Reinecke, M; Reiter, K; Rueckert, L; Ruland, J; Ruprecht, B; Schlegl, J; Schmidt, T; Schneider, S; Schoof, M; Spiekermann, K; Tõnisson, N; Vick, B; Vooder, T; Walch, A; Wilhelm, M; Wu, Z; Zecha, J; Zolg, DP | 1 |
| Aloia, TPA; Amano, MT; Bizzarro, B; Gama, SM; Hernandes, C; Pereira, WO; Ribeiro, NM; Varela, VA | 1 |
| Jin, Y; Liu, H; Meng, H; Qian, W; Yang, C; Yang, X; You, L | 1 |
| Freeman, CL; Giles, FJ; Keane, N; Krawczyk, J; O'Dwyer, M; Swords, R | 1 |
| Bontadini, A; Bortul, R; Chiarini, F; Cocco, L; Evangelisti, C; Martelli, AM; Martinelli, G; McCubrey, JA; Papa, V; Ricci, F; Tabellini, G; Tazzari, PL | 1 |
| Billi, AM; Cappellini, A; Chiarini, F; Evangelisti, C; Martelli, AM; Martinelli, G; McCubrey, JA; Ottaviani, E; Papa, V; Ricci, F; Tazzari, PL; Testoni, N | 1 |
1 review(s) available for perifosine and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Perifosine--a new option in treatment of acute myeloid leukemia?
Topics: Antineoplastic Agents; Clinical Trials as Topic; Humans; Leukemia, Myeloid, Acute; Molecular Structure; Molecular Targeted Therapy; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Signal Transduction; Treatment Outcome | 2013 |
5 other study(ies) available for perifosine and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
The target landscape of clinical kinase drugs.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytokines; Drug Discovery; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Mice; Molecular Targeted Therapy; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proteomics; Xenograft Model Antitumor Assays | 2017 |
AKT inhibition interferes with the expression of immune checkpoint proteins and increases NK-induced killing of HL60-AML cells.
Topics: Animals; HL-60 Cells; Humans; Immune Checkpoint Proteins; Leukemia, Myeloid, Acute; Mice; Mice, Nude; Proto-Oncogene Proteins c-akt | 2023 |
SNS-032 inhibits mTORC1/mTORC2 activity in acute myeloid leukemia cells and has synergistic activity with perifosine against Akt.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cell Proliferation; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Male; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Multiprotein Complexes; Oxazoles; Phosphorylation; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Thiazoles; TOR Serine-Threonine Kinases; Tumor Cells, Cultured | 2013 |
Synergistic proapoptotic activity of recombinant TRAIL plus the Akt inhibitor Perifosine in acute myelogenous leukemia cells.
Topics: Apoptosis; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 8; Cell Survival; Drug Synergism; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Mitogen-Activated Protein Kinase 9; Phosphorylcholine; Protein Kinase C; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-jun; Reactive Oxygen Species; Receptors, TNF-Related Apoptosis-Inducing Ligand; Recombinant Proteins; TNF-Related Apoptosis-Inducing Ligand; X-Linked Inhibitor of Apoptosis Protein | 2008 |
Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells.
Topics: Apoptosis; bcl-Associated Death Protein; Blotting, Western; Cell Proliferation; Colony-Forming Units Assay; Fas Ligand Protein; fas Receptor; Flow Cytometry; fms-Like Tyrosine Kinase 3; Humans; Immunoprecipitation; Leukemia, Myeloid, Acute; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured | 2008 |