perifosine has been researched along with Disease Models, Animal in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 9 (81.82) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, H; Li, WJ; Liao, HH; Mou, SQ; Tang, QZ; Wu, HM; Xia, H; Zhang, N; Zhou, ZY | 1 |
| André, N; Berges, R; Borge, L; Bourgarel, V; Braguer, D; Buric, D; Carré, M; Carrier, A; Le Grand, M; Montero, MP; Pasquier, E; Vasseur, S | 1 |
| Chen, L; Dong, J; Kai, J; Wang, Q; Wu, M; Zeng, LH; Zhu, F | 1 |
| Bi, M; Dong, Q; Jiao, X; Zhang, D; Zhang, J; Zhong, F | 1 |
| Chen, R; Hu, G; Hu, J; Liu, J; Liu, W; Ning, R; Wang, Y; Wu, L; Xiong, J; Yang, J | 1 |
| Hong, Y; Shen, J; Zhang, JL; Zhao, Q | 1 |
| Cruz, R; Figg, WD; League-Pascual, JC; Lester-McCully, CM; Peer, CJ; Rodgers, L; Ronner, L; Shandilya, S; Warren, KE | 1 |
| Beijnen, JH; de Vries, NA; van Tellingen, O | 1 |
| Albrecht, S; Becher, OJ; Gall, S; Hambardzumyan, D; Helmy, K; Hiner, RL; Holland, EC; Huse, JT; Jabado, N; MacDonald, TJ; Nazarian, J; Walker, TR | 1 |
| Brodeur, GM | 1 |
| Li, Z; Liewehr, DJ; Steinberg, SM; Tan, F; Thiele, CJ | 1 |
1 review(s) available for perifosine and Disease Models, Animal
| Article | Year |
|---|---|
High-grade glioma mouse models and their applicability for preclinical testing.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Biomarkers, Tumor; Blood-Brain Barrier; Dacarbazine; Disease Models, Animal; Genetic Engineering; Glioblastoma; Mice; Phosphorylcholine; Prognosis; Temozolomide; Transplantation, Heterologous | 2009 |
10 other study(ies) available for perifosine and Disease Models, Animal
| Article | Year |
|---|---|
Combination treatment of perifosine and valsartan showed more efficiency in protecting against pressure overload induced mouse heart failure.
Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Glycogen Synthase Kinase 3 beta; Heart Failure; Male; MAP Kinase Signaling System; Mice, Inbred C57BL; Organ Size; Phosphorylcholine; Pressure; Proto-Oncogene Proteins c-akt; Signal Transduction; Valsartan | 2020 |
Akt targeting as a strategy to boost chemotherapy efficacy in non-small cell lung cancer through metabolism suppression.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Culture Techniques; Cell Cycle Checkpoints; Cell Line, Tumor; Disease Models, Animal; Energy Metabolism; Glycolysis; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Mice; Mitochondria; Paclitaxel; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Signal Transduction; Xenograft Model Antitumor Assays | 2017 |
Akt Inhibitor Perifosine Prevents Epileptogenesis in a Rat Model of Temporal Lobe Epilepsy.
Topics: Animals; Anticonvulsants; Brain; Convulsants; Disease Models, Animal; Epilepsy, Temporal Lobe; Kainic Acid; Male; Neurons; Phosphorylcholine; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2018 |
Role of CIP4 in high glucose induced epithelial--mesenchymal transition of rat peritoneal mesothelial cells.
Topics: Actins; Animals; Cadherins; Cells, Cultured; Dialysis Solutions; Disease Models, Animal; Epithelial-Mesenchymal Transition; Epithelium; Gene Expression Profiling; Glucose; Male; Microtubule-Associated Proteins; Minor Histocompatibility Antigens; Peritoneal Dialysis; Peritoneal Fibrosis; Peritoneum; Phosphorylcholine; Rats; Rats, Wistar; RNA, Small Interfering; Transfection | 2013 |
Decreased carboxylesterases expression and hydrolytic activity in type 2 diabetic mice through Akt/mTOR/HIF-1α/Stra13 pathway.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Blood Glucose; Carboxylic Ester Hydrolases; Diabetes Mellitus, Type 2; Disease Models, Animal; Gene Knockdown Techniques; Glucose; Hep G2 Cells; Hepatocytes; Homeodomain Proteins; Humans; Hydrolysis; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin; Intestines; Liver; Male; Mice, Inbred C57BL; Overweight; Phosphorylcholine; Proto-Oncogene Proteins c-akt; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2015 |
Preclinical evaluation of perifosine as a potential promising anti-rhabdomyosarcoma agent.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Male; MAP Kinase Signaling System; Mice; Mice, SCID; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Rhabdomyosarcoma; Signal Transduction; Xenograft Model Antitumor Assays | 2016 |
Plasma and cerebrospinal fluid pharmacokinetics of select chemotherapeutic agents following intranasal delivery in a non-human primate model.
Topics: Administration, Intranasal; Animals; Antineoplastic Agents; Blood-Brain Barrier; Dacarbazine; Disease Models, Animal; Macaca mulatta; Male; Nasal Absorption; Phosphorylcholine; Temozolomide; Valproic Acid | 2017 |
Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma.
Topics: Animals; Brain Stem Neoplasms; Combined Modality Therapy; Disease Models, Animal; Genetic Engineering; Glioma; Inbreeding; Mice; Mice, Inbred BALB C; Phosphorylcholine; Receptor, Platelet-Derived Growth Factor alpha | 2010 |
Getting into the AKT.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Survival; Clinical Trials as Topic; Disease Models, Animal; Growth Inhibitors; Humans; Mice; Neuroblastoma; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Receptor Protein-Tyrosine Kinases; Transplantation, Heterologous | 2010 |
In vitro and in vivo inhibition of neuroblastoma tumor cell growth by AKT inhibitor perifosine.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Survival; Clinical Trials as Topic; Disease Models, Animal; Growth Inhibitors; Humans; In Vitro Techniques; Kaplan-Meier Estimate; Luciferases; Luminescent Agents; Mice; Mutation; Neuroblastoma; NIH 3T3 Cells; Phosphorylation; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Transplantation, Heterologous | 2010 |