perifosine has been researched along with Carcinoma, Epidermoid in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, GZ; Elrod, HA; Fu, L; Khuri, FR; Li, B; Lin, YD; Oh, Y; Shin, DM; Sun, SY; Tao, H; Yue, P | 1 |
| Schellens, JH; van Blitterswijk, WJ; Verheij, M; Vink, SR | 1 |
| Begg, AC; Lagerwerf, S; Mesman, E; Schellens, JH; van Blitterswijk, WJ; Verheij, M; Vink, SR | 1 |
| Ansari, R; Argiris, A; Cohen, E; Dancey, J; Esparaz, B; Karrison, T; Lu, Y; Mauer, A; Pins, M; Vokes, E; Wong, S | 1 |
| Klarenbeek, JB; van Blitterswijk, WJ; van der Luit, AH; Verheij, M; Vink, SR | 1 |
| Gutkind, JS; Lahusen, T; Patel, V; Sausville, EA; Senderowicz, AM; Sy, T | 1 |
1 trial(s) available for perifosine and Carcinoma, Epidermoid
| Article | Year |
|---|---|
A phase II trial of perifosine, an oral alkylphospholipid, in recurrent or metastatic head and neck cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; p38 Mitogen-Activated Protein Kinases; Phospholipids; Phosphorylcholine; Proto-Oncogene Proteins c-akt | 2006 |
5 other study(ies) available for perifosine and Carcinoma, Epidermoid
| Article | Year |
|---|---|
c-Jun NH2-terminal kinase-dependent upregulation of DR5 mediates cooperative induction of apoptosis by perifosine and TRAIL.
Topics: Animals; Anthracenes; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Glutathione; Head and Neck Neoplasms; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Nude; Phosphorylcholine; Reactive Oxygen Species; Receptors, TNF-Related Apoptosis-Inducing Ligand; RNA, Small Interfering; TNF-Related Apoptosis-Inducing Ligand; Xenograft Model Antitumor Assays | 2010 |
Tumor and normal tissue pharmacokinetics of perifosine, an oral anti-cancer alkylphospholipid.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Female; Head and Neck Neoplasms; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Phosphorylcholine; Tissue Distribution; Vulvar Neoplasms | 2005 |
Radiosensitization of squamous cell carcinoma by the alkylphospholipid perifosine in cell culture and xenografts.
Topics: Animals; Apoptosis; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; G2 Phase; Head and Neck Neoplasms; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphorylcholine; Radiation-Sensitizing Agents; Rhodamines; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Stem Cell Assay; X-Rays | 2006 |
Lipid rafts and metabolic energy differentially determine uptake of anti-cancer alkylphospholipids in lymphoma versus carcinoma cells.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; KB Cells; Lymphoma; Membrane Microdomains; Mice; Phospholipid Ethers; Phospholipids; Phosphorylcholine | 2007 |
Perifosine, a novel alkylphospholipid, induces p21(WAF1) expression in squamous carcinoma cells through a p53-independent pathway, leading to loss in cyclin-dependent kinase activity and cell cycle arrest.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; CDC2 Protein Kinase; Cell Cycle; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; DNA; Head and Neck Neoplasms; Humans; Phosphorylcholine; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |