Page last updated: 2024-09-04

perifosine and ATLL

perifosine has been researched along with ATLL in 1 studies

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cappellini, A; Chiarini, F; Del Sole, M; Follo, MY; Gaboardi, GC; Mantovani, I; Martelli, AM; McCubrey, JA; Mongiorgi, S	1

Other Studies

1 other study(ies) available for perifosine and ATLL

Article	Year
The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resistant human T-acute leukemia cells by a JNK-dependent mechanism. Leukemia, 2008, Volume: 22, Issue:6 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; Caspases; Cell Survival; Cytochromes c; Down-Regulation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Electrophoretic Mobility Shift Assay; Enzyme Activation; Flow Cytometry; Humans; Immunoenzyme Techniques; JNK Mitogen-Activated Protein Kinases; Leukemia-Lymphoma, Adult T-Cell; Membrane Microdomains; Mitochondria; Phosphatidylinositol 3-Kinases; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Tumor Cells, Cultured; Vinblastine	2008

Article

Year

The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resistant human T-acute leukemia cells by a JNK-dependent mechanism.

Leukemia, 2008, Volume: 22, Issue:6

Topics: Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; Caspases; Cell Survival; Cytochromes c; Down-Regulation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Electrophoretic Mobility Shift Assay; Enzyme Activation; Flow Cytometry; Humans; Immunoenzyme Techniques; JNK Mitogen-Activated Protein Kinases; Leukemia-Lymphoma, Adult T-Cell; Membrane Microdomains; Mitochondria; Phosphatidylinositol 3-Kinases; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Tumor Cells, Cultured; Vinblastine

2008