perhexiline has been researched along with Reperfusion Injury in 2 studies
Perhexiline: 2-(2,2-Dicyclohexylethyl)piperidine. Coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Perhexiline is a potent prophylactic anti-anginal agent that has been shown to inhibit myocardial utilization of long-chain fatty acids and to inhibit the mitochondrial enzyme carnitine palmitoyltransferase (CPT)-1." | 1.31 | Effect of perhexiline and oxfenicine on myocardial function and metabolism during low-flow ischemia/reperfusion in the isolated rat heart. ( Horowitz, JD; Kennedy, JA; Kiosoglous, AJ; Murphy, GA; Pelle, MA, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barba, I | 1 |
| Chavarria, L | 1 |
| Ruiz-Meana, M | 1 |
| Mirabet, M | 1 |
| Agulló, E | 1 |
| Garcia-Dorado, D | 1 |
| Kennedy, JA | 1 |
| Kiosoglous, AJ | 1 |
| Murphy, GA | 1 |
| Pelle, MA | 1 |
| Horowitz, JD | 1 |
2 other studies available for perhexiline and Reperfusion Injury
| Article | Year |
|---|---|
Effect of intracellular lipid droplets on cytosolic Ca2+ and cell death during ischaemia-reperfusion injury in cardiomyocytes.
Topics: Animals; Calcium; Cell Death; Cell Hypoxia; Cell Line; Cells, Cultured; Cytoplasmic Granules; Cytoso | 2009 |
Effect of perhexiline and oxfenicine on myocardial function and metabolism during low-flow ischemia/reperfusion in the isolated rat heart.
Topics: Animals; Calcium Channel Blockers; Carnitine O-Palmitoyltransferase; Coronary Circulation; Enzyme In | 2000 |