perhexiline has been researched along with Nervous System Disorders in 10 studies
Perhexiline: 2-(2,2-Dicyclohexylethyl)piperidine. Coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Perhexiline maleate (Pexid) which has been in general use in France with good results for the treatment of angina pectoris since 1973, may be associated with severe side effects including peripheral neuropathy." | 3.66 | Pharmacokinetics of perhexiline maleate in anginal patients with and without peripheral neuropathy. ( Goujet, MA; Simon, P; Singlas, E, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fossati, C | 1 |
| Guistiniani, S | 1 |
| Dick, B | 1 |
| Küpfer, A | 1 |
| Molnàr, J | 1 |
| Braunschweig, S | 1 |
| Preisig, R | 1 |
| Fraser, DM | 2 |
| Campbell, IW | 1 |
| Miller, HC | 2 |
| Bady, B | 1 |
| Bourrat, C | 1 |
| Trillet, M | 1 |
| Girard, PF | 1 |
| Carrier, H | 1 |
| Myers, JB | 2 |
| Sebille, A | 1 |
| Singlas, E | 1 |
| Goujet, MA | 1 |
| Simon, P | 1 |
| Ronthal, M | 1 |
| Epstein, H | 1 |
2 reviews available for perhexiline and Nervous System Disorders
| Article | Year |
|---|---|
[Side-effects of calcium antagonists].
Topics: Calcium Channel Blockers; Cardiovascular Diseases; Drug Hypersensitivity; Drug Interactions; Fendili | 1984 |
[Toxic neurologic manifestations during angina pectoris treatment (perhexiline maleate and amiotadone hydrochloride)].
Topics: Amiodarone; Angina Pectoris; Benzofurans; Cerebrospinal Fluid Proteins; Electromyography; Humans; In | 1978 |
8 other studies available for perhexiline and Nervous System Disorders
| Article | Year |
|---|---|
[Drug hydroxylation disorders (debrisoquin type) in a random sample of the Swiss population].
Topics: Adolescent; Adult; Aged; Debrisoquin; Female; Homozygote; Humans; Hydroxylation; Isoquinolines; Male | 1982 |
Peripheral and autonomic neuropathy after treatment with perhexiline maleate.
Topics: Autonomic Nervous System; Diabetic Neuropathies; Humans; Male; Middle Aged; Nervous System Diseases; | 1977 |
Perhexilline-induced neuropathy.
Topics: Aged; Autonomic Nervous System; Female; Humans; Male; Middle Aged; Nervous System Diseases; Perhexil | 1978 |
Prevalence of perhexiline maleate neurotoxicosis.
Topics: Humans; Nervous System Diseases; Perhexiline | 1979 |
Prevalence of latent perhexiline neuropathy.
Topics: Angina Pectoris; H-Reflex; Humans; Nervous System Diseases; Perhexiline; Piperidines | 1978 |
Pharmacokinetics of perhexiline maleate in anginal patients with and without peripheral neuropathy.
Topics: Aged; Angina Pectoris; Female; Humans; Kinetics; Male; Middle Aged; Nervous System Diseases; Perhexi | 1978 |
Perhexiline maleate neurotoxicity and weight loss.
Topics: Aged; Body Weight; Female; Humans; Male; Middle Aged; Nervous System Diseases; Perhexiline; Piperidi | 1978 |
Polyneuropathy during perhexiline maleate therapy.
Topics: Aged; Humans; Male; Nervous System Diseases; Perhexiline; Piperidines | 1977 |