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perhexiline and Myocardial Infarction

perhexiline has been researched along with Myocardial Infarction in 16 studies

Perhexiline: 2-(2,2-Dicyclohexylethyl)piperidine. Coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.

Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).

Research Excerpts

ExcerptRelevanceReference
"The effects of low-dose perhexiline on the exercise training response of 22 male patients, 14 after myocardial infarction and 8 after coronary artery bypass who underwent exercise training, were examined."9.05Perhexiline during exercise training in coronary heart disease. ( Darby, JF; Ennis, JT; Horgan, JH; Kelly, JG; Teo, KK, 1983)
"The antianginal effect of perhexiline was evaluated in a placebo-controlled double-blind study of 20 patients with stable angina pectoris."9.04[Clinical efficacy of perhexiline maleate in stable angina pectoris (author's transl)]. ( Glogar, D; Linkesch, W; Niederberger, M, 1978)
"A five-year personal experience of the use of perhexiline maleate (Pexid) in the treatment of severe angina pectoris is presented."7.66Perhexiline maleate in the treatment of angina pectoris. Five years of personal clinical experience. ( Wallace, DC, 1978)
"The effects of low-dose perhexiline on the exercise training response of 22 male patients, 14 after myocardial infarction and 8 after coronary artery bypass who underwent exercise training, were examined."5.05Perhexiline during exercise training in coronary heart disease. ( Darby, JF; Ennis, JT; Horgan, JH; Kelly, JG; Teo, KK, 1983)
"The effectiveness of perhexiline maleate in the suppression of ventricular ectopic activity has been studied in 10 patients after myocardial infarction."5.04Long-term effect of perhexiline maleate on ventricular ectopic activity. ( Myburgh, DP, 1978)
"The antianginal effect of perhexiline was evaluated in a placebo-controlled double-blind study of 20 patients with stable angina pectoris."5.04[Clinical efficacy of perhexiline maleate in stable angina pectoris (author's transl)]. ( Glogar, D; Linkesch, W; Niederberger, M, 1978)
"A five-year personal experience of the use of perhexiline maleate (Pexid) in the treatment of severe angina pectoris is presented."3.66Perhexiline maleate in the treatment of angina pectoris. Five years of personal clinical experience. ( Wallace, DC, 1978)
" Perhexiline maleate controlled his symptoms but when the drug was stopped because of side effects an acute inferior myocardial infarction occurred."3.66Recurrence of Prinzmetal angina seven years following aortocoronary bypass surgery: a clinical and angiographic follow-up. ( Crittin, J; Lespérance, J; Mizgala, HF; Théroux, P; Waters, DD, 1979)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199014 (87.50)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bansal, M1
Chan, J1
Leano, R1
Pillans, P1
Horowitz, J1
Marwick, TH1
Lai, B1
Teo, KK1
Kelly, JG1
Darby, JF1
Ennis, JT1
Horgan, JH1
Dipalma, JR1
Nayler, WG1
Seth, SD1
Gupta, MP1
Kaur, AH1
Basu, AK1
Klassen, GA1
Zborowska-Sluis, DT1
Wright, GJ1
Wallace, DC1
de Brito, FS1
Pereira, MH1
Castro, I1
Maia, IG1
Lhermitte, F1
Fardeau, M1
Chedru, F1
Mallecourt, J1
Crittin, J1
Mizgala, HF1
Waters, DD1
Théroux, P1
Lespérance, J1
Myburgh, DP1
Linkesch, W1
Glogar, D1
Niederberger, M1
Detilleux, JM1
Rausin, G1
Daniell, HB1
Privitera, PJ1
Conradi, SE1
Gaffney, TE1
Roche, P1

Trials

5 trials available for perhexiline and Myocardial Infarction

ArticleYear
Effects of perhexiline on myocardial deformation in patients with ischaemic left ventricular dysfunction.
    International journal of cardiology, 2010, Mar-04, Volume: 139, Issue:2

    Topics: Aged; Cardiotonic Agents; Cardiovascular Agents; Dobutamine; Echocardiography; Exercise Test; Female

2010
Perhexiline during exercise training in coronary heart disease.
    Clinical pharmacology and therapeutics, 1983, Volume: 34, Issue:6

    Topics: Coronary Disease; Heart Function Tests; Heart Rate; Humans; Liver Function Tests; Male; Middle Aged;

1983
[Propafenon in ventricular arrhythmia caused by ischemic cardiopathy. Quantitative study using the Holter system].
    Arquivos brasileiros de cardiologia, 1979, Volume: 33, Issue:4

    Topics: Administration, Oral; Adult; Aged; Cardiac Complexes, Premature; Clinical Trials as Topic; Female; H

1979
Long-term effect of perhexiline maleate on ventricular ectopic activity.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1978, Apr-01, Volume: 53, Issue:13

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Humans; Male; Middle Aged; M

1978
[Clinical efficacy of perhexiline maleate in stable angina pectoris (author's transl)].
    Wiener klinische Wochenschrift, 1978, Sep-01, Volume: 90, Issue:16

    Topics: Adult; Aged; Angina Pectoris; Double-Blind Method; Exercise Test; Heart Rate; Humans; Middle Aged; M

1978

Other Studies

11 other studies available for perhexiline and Myocardial Infarction

ArticleYear
Hypoglycaemia after treatment with perhexiline maleate: a case report.
    The New Zealand medical journal, 2011, Mar-04, Volume: 124, Issue:1330

    Topics: Aged, 80 and over; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug

2011
Calcium channel blockers.
    American family physician, 1983, Volume: 27, Issue:2

    Topics: Angina Pectoris; Angina Pectoris, Variant; Arrhythmias, Cardiac; Calcium Channel Blockers; Diltiazem

1983
Calcium antagonists.
    European heart journal, 1980, Volume: 1, Issue:3

    Topics: Angina Pectoris; Calcium Channel Blockers; Cell Membrane; Diltiazem; Heart; Humans; Hypertension; Mu

1980
Effect of perhexilene on 86Rb uptake in experimental myocardial infarction.
    Indian journal of experimental biology, 1981, Volume: 19, Issue:8

    Topics: Animals; Biological Transport, Active; Disease Models, Animal; Female; Heart; Isoproterenol; Male; M

1981
Effects of oral perhexiline on canine myocardial flow distribution.
    Canadian journal of physiology and pharmacology, 1980, Volume: 58, Issue:5

    Topics: Animals; Blood Pressure; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Heart Rate; M

1980
Perhexiline maleate in the treatment of angina pectoris. Five years of personal clinical experience.
    The Medical journal of Australia, 1978, Nov-04, Volume: 2, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Australia; Drug Therapy, Combination; Fem

1978
Polyneuropathy after perhexiline maleate therapy.
    British medical journal, 1976, May-22, Volume: 1, Issue:6020

    Topics: Humans; Male; Middle Aged; Myocardial Infarction; Perhexiline; Peripheral Nervous System Diseases; P

1976
Recurrence of Prinzmetal angina seven years following aortocoronary bypass surgery: a clinical and angiographic follow-up.
    Catheterization and cardiovascular diagnosis, 1979, Volume: 5, Issue:2

    Topics: Adult; Angina Pectoris; Angina Pectoris, Variant; Coronary Artery Bypass; Electrocardiography; Follo

1979
[Papillary edema and perhexiline maleate].
    Bulletin de la Societe belge d'ophtalmologie, 1978, Issue:180

    Topics: Aged; Coronary Disease; Female; Humans; Male; Middle Aged; Myocardial Infarction; Papilledema; Perhe

1978
Effects of perhexiline on survival time and infarct size in experimental myocardial infarction.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 200, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Vessels; Creatine Kinase; Dogs; Electrocardi

1977
[Letter: Perhexiline maleate and extrapyramidal syndrome].
    La Nouvelle presse medicale, 1975, Feb-01, Volume: 4, Issue:5

    Topics: Aged; Basal Ganglia Diseases; Coronary Disease; Humans; Male; Maleates; Myocardial Infarction; Perhe

1975