perhexiline has been researched along with Liver Cirrhosis in 10 studies
Perhexiline: 2-(2,2-Dicyclohexylethyl)piperidine. Coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors report the cases of 2 patients who died from cirrhosis after receiving perhexiline maleate, a drug widely used in Europe for the treatment of angina pectoris." | 3.66 | Perhexiline maleate-induced cirrhosis. ( Benhamou, JP; Bichara, M; Degott, C; Feldmann, G; Pessayre, D; Potet, F, 1979) |
| "Perhexiline maleate is a potent anti-anginal drug which may cause alcoholic-type hepatitis and cirrhosis." | 1.27 | Perhexiline maleate induced cirrhosis. ( Dunn, D; Pieterse, AS; Rowland, R, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heathfield, KW | 1 |
| Carabott, F | 1 |
| Hay, DR | 1 |
| Gwynne, JF | 1 |
| Robson, RA | 1 |
| Wing, LM | 1 |
| Rouzioux, JM | 1 |
| Malicier, D | 1 |
| Pieterse, AS | 1 |
| Rowland, R | 1 |
| Dunn, D | 1 |
| Pessayre, D | 1 |
| Bichara, M | 1 |
| Degott, C | 1 |
| Potet, F | 1 |
| Benhamou, JP | 1 |
| Feldmann, G | 1 |
| Bertrand, L | 1 |
| Baldet, P | 1 |
| Blanc, F | 1 |
| Puyeo, J | 1 |
| Roche, J | 1 |
| Fournet, J | 1 |
| Meullenet, J | 1 |
| Faure, H | 1 |
| Massot, C | 1 |
| Beaugrand, M | 1 |
| Chousterman, M | 1 |
| Callard, P | 1 |
| Camilleri, JP | 1 |
| Petite, J | 1 |
| Ferrier, JP | 1 |
| Bonnet, P | 1 |
| Jourdan, J | 1 |
| Janbon, F | 1 |
| Michel, H | 1 |
| Bertrand, A | 1 |
1 review available for perhexiline and Liver Cirrhosis
| Article | Year |
|---|---|
[Cirrhogenic hepatitis due to perhexiline maleate: general review based upon one new case with ultrastructural study (author's transl)].
Topics: Aged; Angina Pectoris; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Female; Hepa | 1978 |
9 other studies available for perhexiline and Liver Cirrhosis
| Article | Year |
|---|---|
Adverse effects of perhexiline.
Topics: Adult; Aged; Angina Pectoris; Female; Humans; Liver Cirrhosis; Male; Perhexiline; Peripheral Nervous | 1982 |
Cirrhosis of the liver following therapy with perhexiline maleate.
Topics: Humans; Liver; Liver Cirrhosis; Male; Middle Aged; Perhexiline; Piperidines | 1983 |
Perhexiline and liver cirrhosis.
Topics: Dose-Response Relationship, Drug; Humans; Kinetics; Liver Cirrhosis; Perhexiline; Piperidines | 1983 |
[Calling into question medical responsibility in a death following prolonged treatment with perhexiline maleate].
Topics: France; Humans; Liver Cirrhosis; Long-Term Care; Male; Malpractice; Middle Aged; Perhexiline; Piperi | 1982 |
Perhexiline maleate induced cirrhosis.
Topics: Aged; Angina Pectoris; Female; Humans; Liver; Liver Cirrhosis; Perhexiline; Piperidines | 1983 |
Perhexiline maleate-induced cirrhosis.
Topics: Aged; Angina Pectoris; Chemical and Drug Induced Liver Injury; Cytoplasmic Granules; Female; Hepatic | 1979 |
[Acute hepatic failure due to perhexiline maleate].
Topics: Aged; Angina Pectoris; Chemical and Drug Induced Liver Injury; Humans; Liver Cirrhosis; Male; Perhex | 1979 |
[Hepatitis due to perhexiline maleate. Development of cirrhosis after interruption of the drug. Report of two cases (author's transl)].
Topics: Aged; Chemical and Drug Induced Liver Injury; Humans; Liver; Liver Cirrhosis; Male; Middle Aged; Per | 1977 |
[Liver cirrhosis after 2 years of perhexiline maleate treatment].
Topics: Angina Pectoris; Diagnosis, Differential; Hepatitis, Alcoholic; Humans; Liver Cirrhosis; Male; Middl | 1978 |