perhexiline has been researched along with Leucocythaemia in 1 studies
Perhexiline: 2-(2,2-Dicyclohexylethyl)piperidine. Coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we applied a broad spectrum of technologies including RNA sequencing, global untargeted metabolomics, and stable isotope labeling mass spectrometry to identify metabolic changes in P-glycoprotein overexpressing T-cell acute lymphoblastic leukemia (ALL) cells, which escaped a therapeutically relevant daunorubicin treatment." | 7.81 | Rewired metabolism in drug-resistant leukemia cells: a metabolic switch hallmarked by reduced dependence on exogenous glutamine. ( Bhuiyan, H; Broom, OJ; Islam, S; Lehtiö, J; Lindahl, A; Linnarsson, S; Nordström, A; Stäubert, C; Zhu, Y, 2015) |
| " Here, we applied a broad spectrum of technologies including RNA sequencing, global untargeted metabolomics, and stable isotope labeling mass spectrometry to identify metabolic changes in P-glycoprotein overexpressing T-cell acute lymphoblastic leukemia (ALL) cells, which escaped a therapeutically relevant daunorubicin treatment." | 3.81 | Rewired metabolism in drug-resistant leukemia cells: a metabolic switch hallmarked by reduced dependence on exogenous glutamine. ( Bhuiyan, H; Broom, OJ; Islam, S; Lehtiö, J; Lindahl, A; Linnarsson, S; Nordström, A; Stäubert, C; Zhu, Y, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stäubert, C | 1 |
| Bhuiyan, H | 1 |
| Lindahl, A | 1 |
| Broom, OJ | 1 |
| Zhu, Y | 1 |
| Islam, S | 1 |
| Linnarsson, S | 1 |
| Lehtiö, J | 1 |
| Nordström, A | 1 |
1 other study available for perhexiline and Leucocythaemia
| Article | Year |
|---|---|
Rewired metabolism in drug-resistant leukemia cells: a metabolic switch hallmarked by reduced dependence on exogenous glutamine.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acetyl-CoA C-Acyltransferase; Antineoplastic Agents; ATP Binding C | 2015 |