perhexiline has been researched along with Hepatic Encephalopathy in 1 studies
Perhexiline: 2-(2,2-Dicyclohexylethyl)piperidine. Coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.
Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors report the cases of 2 patients who died from cirrhosis after receiving perhexiline maleate, a drug widely used in Europe for the treatment of angina pectoris." | 3.66 | Perhexiline maleate-induced cirrhosis. ( Benhamou, JP; Bichara, M; Degott, C; Feldmann, G; Pessayre, D; Potet, F, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pessayre, D | 1 |
| Bichara, M | 1 |
| Degott, C | 1 |
| Potet, F | 1 |
| Benhamou, JP | 1 |
| Feldmann, G | 1 |
1 other study available for perhexiline and Hepatic Encephalopathy
| Article | Year |
|---|---|
Perhexiline maleate-induced cirrhosis.
Topics: Aged; Angina Pectoris; Chemical and Drug Induced Liver Injury; Cytoplasmic Granules; Female; Hepatic | 1979 |