perhexiline has been researched along with Complication, Postoperative in 2 studies
Perhexiline: 2-(2,2-Dicyclohexylethyl)piperidine. Coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Perhexiline was associated with a reduction in the cardiac index at 6 h [difference in means 0." | 2.80 | The effect of perhexiline on myocardial protection during coronary artery surgery: a two-centre, randomized, double-blind, placebo-controlled trial. ( Calvert, MJ; Drury, NE; Freemantle, N; Frenneaux, MP; Graham, TR; Green, DH; Howell, NJ; Hyde, JA; Lewis, ME; Mascaro, JG; Pagano, D; Rooney, SJ; Senanayake, EL; Viant, MR; Weber, RJ; Wilson, IC, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Drury, NE | 1 |
| Howell, NJ | 1 |
| Calvert, MJ | 1 |
| Weber, RJ | 1 |
| Senanayake, EL | 1 |
| Lewis, ME | 1 |
| Hyde, JA | 1 |
| Green, DH | 1 |
| Mascaro, JG | 1 |
| Wilson, IC | 1 |
| Graham, TR | 1 |
| Rooney, SJ | 1 |
| Viant, MR | 1 |
| Freemantle, N | 1 |
| Frenneaux, MP | 1 |
| Pagano, D | 1 |
| Roberts, RK | 1 |
| Cohn, D | 1 |
| Petroff, V | 1 |
| Seneviratne, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Metabolic Support With Perhexiline to Protect Myocardium Undergoing Coronary Artery Surgery[NCT00845364] | Phase 2/Phase 3 | 290 participants (Actual) | Interventional | 2007-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for perhexiline and Complication, Postoperative
| Article | Year |
|---|---|
The effect of perhexiline on myocardial protection during coronary artery surgery: a two-centre, randomized, double-blind, placebo-controlled trial.
Topics: Aged; Cardiac Output; Cardiotonic Agents; Coronary Artery Bypass; Coronary Vessels; Double-Blind Met | 2015 |
1 other study available for perhexiline and Complication, Postoperative
| Article | Year |
|---|---|
Liver disease induced by perhexiline maleate.
Topics: Angina Pectoris; Chemical and Drug Induced Liver Injury; Humans; Liver; Liver Cirrhosis, Alcoholic; | 1981 |