perhexiline has been researched along with Chronic Illness in 9 studies
Perhexiline: 2-(2,2-Dicyclohexylethyl)piperidine. Coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Perhexiline treatment also increased resting and peak dobutamine stress regional myocardial function (by 15% and 24%, respectively) and normalized skeletal muscle phosphocreatine recovery after exercise." | 6.71 | Metabolic modulation with perhexiline in chronic heart failure: a randomized, controlled trial of short-term use of a novel treatment. ( Ashrafian, H; Campbell, R; Clarke, K; Fraser, AG; Frenneaux, M; Gunaruwan, P; Horowitz, J; Lee, L; Scheuermann-Freestone, M; Taylor, R; Williams, L, 2005) |
| "Perhexiline treatment also increased resting and peak dobutamine stress regional myocardial function (by 15% and 24%, respectively) and normalized skeletal muscle phosphocreatine recovery after exercise." | 2.71 | Metabolic modulation with perhexiline in chronic heart failure: a randomized, controlled trial of short-term use of a novel treatment. ( Ashrafian, H; Campbell, R; Clarke, K; Fraser, AG; Frenneaux, M; Gunaruwan, P; Horowitz, J; Lee, L; Scheuermann-Freestone, M; Taylor, R; Williams, L, 2005) |
| "Perhexiline maleate is an antianginal agent which depends on hepatic oxidation for its elimination." | 1.27 | Impaired oxidation of debrisoquine in patients with perhexiline liver injury. ( Morgan, MY; Oates, NS; Reshef, R; Shah, RR; Sherlock, S; Smith, RL, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (77.78) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jawad, E | 1 |
| Arora, R | 1 |
| Lee, L | 1 |
| Campbell, R | 1 |
| Scheuermann-Freestone, M | 1 |
| Taylor, R | 1 |
| Gunaruwan, P | 1 |
| Williams, L | 1 |
| Ashrafian, H | 1 |
| Horowitz, J | 1 |
| Fraser, AG | 1 |
| Clarke, K | 1 |
| Frenneaux, M | 1 |
| Morgan, MY | 1 |
| Reshef, R | 1 |
| Shah, RR | 1 |
| Oates, NS | 1 |
| Smith, RL | 1 |
| Sherlock, S | 1 |
| Luxereau, PH | 1 |
| Acar, J | 1 |
| De'Thomatis, M | 1 |
| Falciola, N | 1 |
| Gallesio, R | 1 |
| Candau, LA | 1 |
| Padilha, JC | 1 |
| Tasca, R | 1 |
| de Patta, M | 1 |
| Weiskopf, JS | 1 |
| Scherr, C | 1 |
| Albanese, MC | 1 |
| Feruglio, GA | 1 |
| Luccioni, R | 1 |
| Trigano, JA | 1 |
2 reviews available for perhexiline and Chronic Illness
| Article | Year |
|---|---|
Chronic stable angina pectoris.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetanilides; Angina Pectoris; Antihypertensive Agent | 2008 |
[Medical therapy of chronic coronary insufficiency].
Topics: Amiodarone; Angina Pectoris; Chronic Disease; Coronary Disease; Digitalis Glycosides; Humans; Lidofl | 1978 |
2 trials available for perhexiline and Chronic Illness
| Article | Year |
|---|---|
Metabolic modulation with perhexiline in chronic heart failure: a randomized, controlled trial of short-term use of a novel treatment.
Topics: Aged; Cardiovascular Agents; Chronic Disease; Echocardiography, Stress; Fatty Acids; Female; Glucose | 2005 |
Proceedings: Clinical and statistical evaluation of the effect of perhexiline maleate in patients with chronic angina.
Topics: Angina Pectoris; Chronic Disease; Clinical Trials as Topic; Humans; Middle Aged; Perhexiline; Piperi | 1973 |
5 other studies available for perhexiline and Chronic Illness
| Article | Year |
|---|---|
Impaired oxidation of debrisoquine in patients with perhexiline liver injury.
Topics: Adolescent; Adult; Aged; Angina Pectoris; Chemical and Drug Induced Liver Injury; Chronic Disease; D | 1984 |
[Letter: Perhexilinemaleate in patients suffering from chronic coronary failure].
Topics: Adult; Aged; Chronic Disease; Coronary Disease; Drug Tolerance; Female; Humans; Male; Maleates; Midd | 1976 |
Drug treatment of chronic stable angina pectoris.
Topics: Angina Pectoris; Chronic Disease; Humans; Nifedipine; Nitrites; Perhexiline; Verapamil | 1978 |
[Comparative study of the medium term use of verapamil and perhexiline in the treatment of chronic coronary insufficiency. Clinical and cycloergometric evaluation].
Topics: Adult; Aged; Chronic Disease; Coronary Disease; Electrocardiography; Exercise Test; Female; Humans; | 1978 |
[Anti-arrhythmic action of perhexiline maleate in chronic coronary insufficiency].
Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chronic Disease; Coronary Disease; Drug Evaluat | 1977 |