Page last updated: 2024-11-02

perhexiline and Body Weight

perhexiline has been researched along with Body Weight in 11 studies

Perhexiline: 2-(2,2-Dicyclohexylethyl)piperidine. Coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"Perhexiline has become a "last-line" agent for refractory angina as a result of complex pharmacokinetics and potential toxicity."5.37Effects of aging, renal dysfunction, left ventricular systolic impairment, and weight on steady state pharmacokinetics of perhexiline. ( Averbuj, P; Chik, W; Horowitz, JD; Ling, LH; Morris, RG; Ngo, DT; Pati, PK; Sallustio, BC; Sverdlov, AL, 2011)
"Perhexiline has become a "last-line" agent for refractory angina as a result of complex pharmacokinetics and potential toxicity."1.37Effects of aging, renal dysfunction, left ventricular systolic impairment, and weight on steady state pharmacokinetics of perhexiline. ( Averbuj, P; Chik, W; Horowitz, JD; Ling, LH; Morris, RG; Ngo, DT; Pati, PK; Sallustio, BC; Sverdlov, AL, 2011)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-199010 (90.91)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ling, LH1
Chik, W1
Averbuj, P1
Pati, PK1
Sverdlov, AL1
Ngo, DT1
Morris, RG1
Sallustio, BC1
Horowitz, JD2
Hoenig, V2
Werner, F2
Jung, HJ1
Suzuki, K1
Mashford, ML1
Cousteau, JP1
Singlas, E1
Assan, R1
Myers, JB1
Ronthal, M1
Corsini, G1
Correale, E1
Oriani, G1
Persico, S1
Tritto, C1
Grand, A1
Sepulchre, P1
Hoekenga, MT1
Bunde, CA1
Cawein, MJ1
Kuzma, RJ1
Griffin, CL1
Datey, KK1
Dalvi, CP1
Kelkar, PN1
Bhootra, RK1

Trials

3 trials available for perhexiline and Body Weight

ArticleYear
[Clinical trial by perexiline maleate in treatment of angina pectoris (author's transl)].
    Giornale italiano di cardiologia, 1975, Volume: 5, Issue:1

    Topics: Angina Pectoris; Blood Pressure; Body Weight; Drug Evaluation; Electrocardiography; Headache; Humans

1975
Proceedings: Clinical results with a new antianginal drug (perhexiline maleate).
    Postgraduate medical journal, 1973, Volume: 49

    Topics: Angina Pectoris; Body Weight; Clinical Trials as Topic; Humans; Perhexiline; Piperidines; Vasodilato

1973
Perhexiline maleate, a new anti-anginal drug, evaluated by "modified double blind double cross over study".
    Angiology, 1974, Volume: 25, Issue:6

    Topics: Administration, Oral; Adult; Aged; Alanine Transaminase; Angina Pectoris; Blood Pressure; Body Weigh

1974

Other Studies

8 other studies available for perhexiline and Body Weight

ArticleYear
Effects of aging, renal dysfunction, left ventricular systolic impairment, and weight on steady state pharmacokinetics of perhexiline.
    Therapeutic drug monitoring, 2011, Volume: 33, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Angina Pectoris; Body Weight; Cardiovascular Agents; Creatinine; Hum

2011
Effect of perhexiline maleate on bile formation and liver disposition of sulfobromophthalein in the rat.
    Pharmacological research communications, 1980, Volume: 12, Issue:10

    Topics: Animals; Bile; Bile Acids and Salts; Body Weight; Liver; Male; Perhexiline; Piperidines; Propylene G

1980
Morphological changes in CNS of rats treated with perhexiline maleate (pexid).
    Acta neuropathologica, 1978, Jun-30, Volume: 42, Issue:3

    Topics: Animals; Astrocytes; Body Weight; Brain; Central Nervous System; Endothelium; Ependyma; Fibroblasts;

1978
Long-term safety of perhexiline maleate.
    The Medical journal of Australia, 1979, Mar-24, Volume: 1, Issue:6

    Topics: Angina Pectoris; Body Weight; Humans; Liver Diseases; Neuromuscular Diseases; Perhexiline; Piperidin

1979
Effect of perhexiline maleate on lipid metabolism in the rat.
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:9

    Topics: Animals; Body Weight; Lipid Metabolism; Lipids; Liver; Lung; Male; Organ Size; Perhexiline; Piperidi

1979
[Can one give perhexiline to diabetics?].
    Journees annuelles de diabetologie de l'Hotel-Dieu, 1978

    Topics: Angina Pectoris; Body Weight; Chemical and Drug Induced Liver Injury; Diabetes Complications; Diabet

1978
Perhexiline maleate neurotoxicity and weight loss.
    The Medical journal of Australia, 1978, Nov-04, Volume: 2, Issue:10

    Topics: Aged; Body Weight; Female; Humans; Male; Middle Aged; Nervous System Diseases; Perhexiline; Piperidi

1978
[Letter: Weight reduction and perhexiline maleate].
    La Nouvelle presse medicale, 1974, Jun-08, Volume: 3, Issue:23

    Topics: Body Weight; Coronary Disease; Diuresis; Feeding and Eating Disorders; Humans; Maleates; Perhexiline

1974