perhexiline has been researched along with Arrhythmias, Cardiac in 20 studies
Perhexiline: 2-(2,2-Dicyclohexylethyl)piperidine. Coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effectiveness of perhexiline maleate in the suppression of ventricular ectopic activity has been studied in 10 patients after myocardial infarction." | 5.04 | Long-term effect of perhexiline maleate on ventricular ectopic activity. ( Myburgh, DP, 1978) |
| "In a preliminary study which lasted 14 weeks, an anti-anginal preparation, perhexiline maleate (Pexid), was prescribed in a dosage of 200 mg twice a day to 7 patients who were suffering from cardiac arrhythmias associated with ischaemic heart disease." | 3.65 | The anti-arrhythmic effects of perhexiline maleate in patients with ischaemic heart disease. ( Gitlin, N, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (95.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jia, L | 1 |
| Sun, H | 1 |
| Opie, LH | 1 |
| Dipalma, JR | 1 |
| Lehmann, HU | 1 |
| Hochrein, H | 1 |
| Bergey, JL | 1 |
| McCallum, JD | 1 |
| Nocella, K | 1 |
| Lancelin, B | 1 |
| Blanchard, D | 1 |
| Aziza, JP | 1 |
| Guermonprez, JL | 1 |
| Maurice, P | 1 |
| Gitlin, N | 2 |
| Myburgh, DP | 1 |
| Albanese, MC | 1 |
| Feruglio, GA | 1 |
| Masoni, A | 1 |
| Tomasi, AM | 1 |
| Oriani, GA | 1 |
| Daniell, HB | 1 |
| Privitera, PJ | 1 |
| Conradi, SE | 1 |
| Gaffney, TE | 1 |
| Cristallo, E | 1 |
| Palma, B | 1 |
| Fino, E | 1 |
| De Luca, I | 1 |
| Albanese, P | 1 |
| Mitolo, E | 1 |
| Garten, J | 1 |
| Werhrschütz, E | 1 |
| Vera, Z | 1 |
| Gray, DR | 1 |
| Harter, KW | 1 |
| Janzen, DA | 1 |
| Massumi, RA | 1 |
| Mason, DT | 1 |
| Psychoyos, S | 1 |
| Bax, M | 1 |
| Atkins, C | 1 |
| Meng, HP | 1 |
| Zhang, BH | 1 |
| Bleifer, DJ | 1 |
| Hansmann, DR | 1 |
| Bleifer, SB | 1 |
| Sheppard, JS | 1 |
| Karpman, HL | 1 |
| Sukerman, M | 1 |
| Drake, FT | 1 |
| Haring, O | 1 |
| Singer, DH | 1 |
| Dirnberger, G | 1 |
1 review available for perhexiline and Arrhythmias, Cardiac
| Article | Year |
|---|---|
[Indications for use of calcium antagonists].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Cardiotonic Agents; Coronary Disease | 1980 |
6 trials available for perhexiline and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Long-term effect of perhexiline maleate on ventricular ectopic activity.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Humans; Male; Middle Aged; M | 1978 |
Clinical evaluation of perhexiline maleate in the treatment of patients with chronic coronary insufficiency.
Topics: Administration, Oral; Aged; Alanine Transaminase; Angina Pectoris; Animals; Arrhythmias, Cardiac; As | 1975 |
[Pexide, a new coronary drug].
Topics: Angina Pectoris; Animals; Arrhythmias, Cardiac; Clinical Trials as Topic; Dogs; Hemodynamics; Humans | 1975 |
Proceedings: Clinical evaluation of perhexiline maleate in the treatment of chronic cardiac arrhythmias of patients with coronary heart disease.
Topics: Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Disease; Electrocardiography; Female; | 1973 |
Proceedings: Evaluation of anti-arrhythmic efficacy of perhexiline maleate in ambulatory patients by Holter monitoring.
Topics: Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Electrocardiography; Female; Humans; Ma | 1973 |
Perhexiline maleate in the management of patients with angina pectoris. A long-term assessment.
Topics: Aged; Angina Pectoris; Arrhythmias, Cardiac; Aspartate Aminotransferases; Clinical Trials as Topic; | 1974 |
13 other studies available for perhexiline and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant | 2008 |
Drugs and the heart. III. Calcium antagonists.
Topics: Angina Pectoris; Aniline Compounds; Arrhythmias, Cardiac; Calcium; Cardiomegaly; Diuretics; Heart Di | 1980 |
Calcium channel blockers.
Topics: Angina Pectoris; Angina Pectoris, Variant; Arrhythmias, Cardiac; Calcium Channel Blockers; Diltiazem | 1983 |
Antiarrhythmic evaluation of verapamil, nifedipine, perhexiline and skf 525-A in four canine models of cardiac arrhythmias.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Calcium; Dogs; Female; Heart | 1981 |
[Calcium inhibitors. Current indications in cardiology].
Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium; Cardiovascular Diseases; Diltiazem; Humans; Nifedipi | 1980 |
The anti-arrhythmic effects of perhexiline maleate in patients with ischaemic heart disease.
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Complexes, Premature; Coronary Disease; Female; H | 1975 |
[Anti-arrhythmic action of perhexiline maleate in chronic coronary insufficiency].
Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chronic Disease; Coronary Disease; Drug Evaluat | 1977 |
Effects of perhexiline on survival time and infarct size in experimental myocardial infarction.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Vessels; Creatine Kinase; Dogs; Electrocardi | 1977 |
[Antiarrhythmic and antianginose activity of perhexiline maleate].
Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Drug Evaluation; Female; Humans; Male; Middle Ag | 1977 |
Electrophysiologic properties of perhexiline.
Topics: Animals; Arrhythmias, Cardiac; Bundle of His; Dogs; Electric Stimulation; Electrocardiography; Heart | 1975 |
Differences in Ca2+ entry blockers revealed by effects on adenosine- and adrenergic- receptors and cyclic AMP levels of [2-3H]adenine-prelabeled vesicles prepared from guinea pig brain.
Topics: Adenine; Adenosine; Animals; Arrhythmias, Cardiac; Brain Chemistry; Calcium Channel Blockers; Cell M | 1986 |
[Cardiovascular effects of N-ethyl perhexiline maleate in animals].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Guinea Pigs; Heart Rate; Hemodynamics; | 1985 |
Continuous ECG (Holter) recordings in the evaluation of antiarrhythmic drugs.
Topics: Arrhythmias, Cardiac; Cardiac Complexes, Premature; Disopyramide; Drug Evaluation; Electrocardiograp | 1974 |