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perhexiline and Angina at Rest

perhexiline has been researched along with Angina at Rest in 2 studies

Perhexiline: 2-(2,2-Dicyclohexylethyl)piperidine. Coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.

Research Excerpts

ExcerptRelevanceReference
"Perhexiline maleate, which causes inhibition of myocardial fatty acid catabolism with a concomitant increase in glucose utilization, is particularly useful in the management of patients with severe angina pectoris."7.67Perhexiline maleate treatment for severe angina pectoris--correlations with pharmacokinetics. ( Goble, AJ; Horowitz, JD; Louis, WJ; Macdonald, PS; Sia, ST, 1986)
"We tested the hypothesis that resolution versus persistence of symptomatic ischaemia and/or development of nausea/dizziness on the third day of loading with perhexiline maleate (PM), is correlated with perhexiline plasma concentrations after the standard loading phase in patients with acute coronary syndromes."5.08Relationship between plasma perhexiline concentration and symptomatic status during short-term perhexiline therapy. ( Horowitz, JD; Northey, DL; Stewart, S; Voss, DW, 1996)
"Perhexiline maleate, which causes inhibition of myocardial fatty acid catabolism with a concomitant increase in glucose utilization, is particularly useful in the management of patients with severe angina pectoris."3.67Perhexiline maleate treatment for severe angina pectoris--correlations with pharmacokinetics. ( Goble, AJ; Horowitz, JD; Louis, WJ; Macdonald, PS; Sia, ST, 1986)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stewart, S1
Voss, DW1
Northey, DL1
Horowitz, JD2
Sia, ST1
Macdonald, PS1
Goble, AJ1
Louis, WJ1

Trials

1 trial available for perhexiline and Angina at Rest

ArticleYear
Relationship between plasma perhexiline concentration and symptomatic status during short-term perhexiline therapy.
    Therapeutic drug monitoring, 1996, Volume: 18, Issue:6

    Topics: Aged; Aged, 80 and over; Angina, Unstable; Calcium Channel Blockers; Cardiovascular Agents; Dizzines

1996

Other Studies

1 other study available for perhexiline and Angina at Rest

ArticleYear
Perhexiline maleate treatment for severe angina pectoris--correlations with pharmacokinetics.
    International journal of cardiology, 1986, Volume: 13, Issue:2

    Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Drug Administration Schedule; Female; Humans; Kineti

1986